Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes RJ McKenney, W Huynh, ME Tanenbaum, G Bhabha, RD Vale Science 345 (6194), 337-341, 2014 | 586 | 2014 |
LIS1 and NudE induce a persistent dynein force-producing state RJ McKenney, M Vershinin, A Kunwar, RB Vallee, SP Gross Cell 141 (2), 304-314, 2010 | 413 | 2010 |
Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport A Kunwar, SK Tripathy, J Xu, MK Mattson, P Anand, R Sigua, M Vershinin, ... Proceedings of the National Academy of Sciences 108 (47), 18960-18965, 2011 | 220 | 2011 |
Tyrosination of α‐tubulin controls the initiation of processive dynein–dynactin motility RJ McKenney, W Huynh, RD Vale, M Sirajuddin The EMBO journal 35 (11), 1175-1185, 2016 | 216 | 2016 |
Multiple modes of cytoplasmic dynein regulation RB Vallee, RJ McKenney, KM Ori-McKenney Nature cell biology 14 (3), 224-230, 2012 | 204 | 2012 |
NudE and NudEL are required for mitotic progression and are involved in dynein recruitment to kinetochores SA Stehman, Y Chen, RJ McKenney, RB Vallee The Journal of cell biology 178 (4), 583-594, 2007 | 182 | 2007 |
Microtubules gate tau condensation to spatially regulate microtubule functions R Tan, AJ Lam, T Tan, J Han, DW Nowakowski, M Vershinin, S Simó, ... Nature cell biology 21 (9), 1078-1085, 2019 | 179 | 2019 |
Mutually exclusive cytoplasmic dynein regulation by NudE-Lis1 and dynactin RJ McKenney, SJ Weil, J Scherer, RB Vallee Journal of Biological Chemistry 286 (45), 39615-39622, 2011 | 141 | 2011 |
Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility DA Grotjahn, S Chowdhury, Y Xu, MKJ Richard, T Schroer, GC Lander Biophysical Journal 114 (3), 194a, 2018 | 138 | 2018 |
A combinatorial MAP code dictates polarized microtubule transport BY Monroy, TC Tan, JM Oclaman, JS Han, S Simó, S Niwa, ... Developmental cell 53 (1), 60-72. e4, 2020 | 128 | 2020 |
High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport JY Yi, KM Ori-McKenney, RJ McKenney, M Vershinin, SP Gross, ... Journal of Cell Biology 195 (2), 193-201, 2011 | 122 | 2011 |
Phosphorylation of β-tubulin by the Down syndrome kinase, minibrain/DYRK1a, regulates microtubule dynamics and dendrite morphogenesis KM Ori-McKenney, RJ McKenney, HH Huang, T Li, S Meltzer, LY Jan, ... Neuron 90 (3), 551-563, 2016 | 100 | 2016 |
Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors K Chiba, H Takahashi, M Chen, H Obinata, S Arai, K Hashimoto, T Oda, ... Proceedings of the National Academy of Sciences 116 (37), 18429-18434, 2019 | 99 | 2019 |
Polarity of neuronal membrane traffic requires sorting of kinesin motor cargo during entry into dendrites by a microtubule-associated septin EP Karasmanis, CT Phan, D Angelis, IA Kesisova, CC Hoogenraad, ... Developmental cell 46 (2), 204-218. e7, 2018 | 84 | 2018 |
Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains ME Tanenbaum, RD Vale, RJ McKenney Elife 2, e00943, 2013 | 84 | 2013 |
Differential effects of the dynein-regulatory factor Lissencephaly-1 on processive dynein-dynactin motility PA Gutierrez, BE Ackermann, M Vershinin, RJ McKenney Journal of Biological Chemistry 292 (29), 12245-12255, 2017 | 75 | 2017 |
Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage EM Bahassi, DL Myer, RJ McKenney, RF Hennigan, PJ Stambrook Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 596 (1 …, 2006 | 73 | 2006 |
Cooperative accumulation of dynein-dynactin at microtubule minus-ends drives microtubule network reorganization R Tan, PJ Foster, DJ Needleman, RJ McKenney Developmental cell 44 (2), 233-247. e4, 2018 | 69 | 2018 |
New insights into the mechanism of dynein motor regulation by lissencephaly-1 SM Markus, MG Marzo, RJ McKenney Elife 9, e59737, 2020 | 58 | 2020 |
Expression patterns of LIS1, dynein and their interaction partners dynactin, NudE, NudEL and NudC in human gliomas suggest roles in invasion and proliferation SO Suzuki, RJ McKenney, S Mawatari, M Mizuguchi, A Mikami, T Iwaki, ... Acta neuropathologica 113, 591-599, 2007 | 49 | 2007 |