TLR9 signals after translocating from the ER to CpG DNA in the lysosome E Latz, A Schoenemeyer, A Visintin, KA Fitzgerald, BG Monks, CF Knetter, ... Nature immunology 5 (2), 190-198, 2004 | 1735 | 2004 |
LPS-TLR4 signaling to IRF-3/7 and NF-κB involves the toll adapters TRAM and TRIF KA Fitzgerald, DC Rowe, BJ Barnes, DR Caffrey, A Visintin, E Latz, ... The Journal of experimental medicine 198 (7), 1043-1055, 2003 | 1611 | 2003 |
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein A Trompette, S Divanovic, A Visintin, C Blanchard, RS Hegde, R Madan, ... Nature 457 (7229), 585-588, 2009 | 876 | 2009 |
Regulation of Toll-like receptors in human monocytes and dendritic cells A Visintin, A Mazzoni, JH Spitzer, DH Wyllie, SK Dower, DM Segal The Journal of Immunology 166 (1), 249-255, 2001 | 848 | 2001 |
Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism A Mazzoni, V Bronte, A Visintin, JH Spitzer, E Apolloni, P Serafini, ... The Journal of Immunology 168 (2), 689-695, 2002 | 838 | 2002 |
Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9 P Parroche, FN Lauw, N Goutagny, E Latz, BG Monks, A Visintin, ... Proceedings of the National Academy of Sciences 104 (6), 1919-1924, 2007 | 696 | 2007 |
Ligand-induced conformational changes allosterically activate Toll-like receptor 9 E Latz, A Verma, A Visintin, M Gong, CM Sirois, DCG Klein, BG Monks, ... Nature immunology 8 (7), 772-779, 2007 | 572 | 2007 |
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal … E Latz, A Visintin, E Lien, KA Fitzgerald, BG Monks, EA Kurt-Jones, ... Journal of Biological Chemistry 277 (49), 47834-47843, 2002 | 569 | 2002 |
Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105 S Divanovic, A Trompette, SF Atabani, R Madan, DT Golenbock, A Visintin, ... Nature immunology 6 (6), 571-578, 2005 | 479 | 2005 |
Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization A Mazzoni, HA Young, JH Spitzer, A Visintin, DM Segal The Journal of clinical investigation 108 (12), 1865-1873, 2001 | 441 | 2001 |
Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses DH Wyllie, E Kiss-Toth, A Visintin, SC Smith, S Boussouf, DM Segal, ... The Journal of Immunology 165 (12), 7125-7132, 2000 | 410 | 2000 |
Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4 A Visintin, A Mazzoni, JA Spitzer, DM Segal Proceedings of the National Academy of Sciences 98 (21), 12156-12161, 2001 | 321 | 2001 |
Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction A Visintin, E Latz, BG Monks, T Espevik, DT Golenbock Journal of Biological Chemistry 278 (48), 48313-48320, 2003 | 294 | 2003 |
The apoptotic response to pneumolysin is Toll-like receptor 4 dependent and protects against pneumococcal disease A Srivastava, P Henneke, A Visintin, SC Morse, V Martin, C Watkins, ... Infection and immunity 73 (10), 6479-6487, 2005 | 235 | 2005 |
Meningococcal porin PorB binds to TLR2 and requires TLR1 for signaling P Massari, A Visintin, J Gunawardana, KA Halmen, CA King, ... The Journal of Immunology 176 (4), 2373-2380, 2006 | 207 | 2006 |
Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2 A Visintin, KA Halmen, E Latz, BG Monks, DT Golenbock The Journal of Immunology 175 (10), 6465-6472, 2005 | 205 | 2005 |
Localization of TLR2 and MyD88 to Chlamydia trachomatis inclusions: evidence for signaling by intracellular TLR2 during infection with an obligate intracellular pathogen CM O'Connell, IA Ionova, AJ Quayle, A Visintin, RR Ingalls Journal of Biological Chemistry 281 (3), 1652-1659, 2006 | 178 | 2006 |
Human factor H interacts selectively with Neisseria gonorrhoeae and results in species-specific complement evasion J Ngampasutadol, S Ram, S Gulati, S Agarwal, C Li, A Visintin, B Monks, ... The Journal of Immunology 180 (5), 3426-3435, 2008 | 166 | 2008 |
Prolonged Upregulation of the Expression of HLA Class I Antigens and Co stimulatory Molecules on Melanoma Cells Treated with 5-aza-2'-deoxycytidine (5-AZA-CdR) S Coral, L Sigalotti, A Gasparollo, I Cattarossi, A Visintin, A Cattelan, ... Journal of immunotherapy 22 (1), 16-24, 1999 | 162 | 1999 |
Mechanisms of TLR9 activation E Latz, A Visintin, T Espevik, DT Golenbock Journal of endotoxin research 10 (6), 406-412, 2004 | 109 | 2004 |