Restricted HIV-1 Env glycan engagement by lectin-reengineered DAVEI protein chimera is sufficient for lytic inactivation of the virus B Parajuli, K Acharya, HC Bach, B Parajuli, S Zhang, AB Smith III, ... Biochemical Journal 475 (5), 931-957, 2018 | 19 | 2018 |
Bifunctional Chimera That Coordinately Targets Human Immunodeficiency Virus 1 Envelope gp120 and the Host-Cell CCR5 Coreceptor at the Virus–Cell Interface AA Rashad, LR Song, AP Holmes, K Acharya, S Zhang, ZL Wang, E Gary, ... Journal of medicinal chemistry 61 (11), 5020-5033, 2018 | 11 | 2018 |
Improved durability to SARS-CoV-2 vaccine immunity following coimmunization with molecular adjuvant adenosine deaminase-1 GM Cusimano, EN Gary, MR Bell, BM Warner, J Connors, NJ Tursi, AR Ali, ... The Journal of Immunology 209 (1), 118-127, 2022 | 4 | 2022 |
Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site TG Caniels, M Medina-Ramìrez, S Zhang, S Kratochvil, Y Xian, JH Koo, ... Science Immunology 9 (98), eadk9550, 2024 | 3 | 2024 |
Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators S Zhang, AP Holmes, A Dick, AA Rashad, L Enríquez Rodríguez, ... Retrovirology 18, 1-18, 2021 | 3 | 2021 |
Peptide Triazole Thiol Irreversibly Inactivates Metastable HIV-1 Env by Accessing Conformational Triggers Intrinsic to Virus–Cell Entry CG Ang, E Carter, A Haftl, S Zhang, AA Rashad, M Kutzler, CF Abrams, ... Microorganisms 9 (6), 1286, 2021 | 3 | 2021 |
Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques AN Nelson, X Shen, S Vekatayogi, S Zhang, G Ozorowski, M Dennis, ... bioRxiv, 2023 | 2 | 2023 |
Immunization with germ line–targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques AN Nelson, X Shen, S Vekatayogi, S Zhang, G Ozorowski, M Dennis, ... Science Immunology 9 (98), eadm7097, 2024 | 1 | 2024 |
Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate B Parajuli, K Acharya, A Nangarlia, S Zhang, B Parajuli, A Dick, B Ngo, ... Biochemical Journal 477 (21), 4263-4280, 2020 | 1 | 2020 |
Germline-targeting chimpanzee SIV Envelopes induce V2-apex broadly neutralizing-like B cell precursors in a rhesus macaque infection model R Musharrafieh, Y Safonova, G Song, RS Roark, FH Lee, S Zhang, ... bioRxiv, 2023.09. 21.558743, 2023 | | 2023 |
Resistance and Synergism in the Antiviral Functions of Peptide Triazole Inactivators of the HIV-1 Env S Zhang Drexel University, 2021 | | 2021 |