| Inhibition of glycolysis and glutaminolysis: an emerging drug discovery approach to combat cancer NS Akins, TC Nielson, HV Le Current topics in medicinal chemistry 18 (6), 494-504, 2018 | 239 | 2018 |
| Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator … JI Juncosa, K Takaya, HV Le, MJ Moschitto, PM Weerawarna, ... Journal of the American Chemical Society 140 (6), 2151-2164, 2018 | 77 | 2018 |
| Trifluoroacetic Anhydride-Catalyzed Oxidation of Isonitriles by DMSO: A Rapid, Convenient Synthesis of Isocyanates HV Le, B Ganem Organic Letters 13 (10), 2584-2585, 2011 | 63 | 2011 |
| Suppression of hepatocellular carcinoma by inhibition of overexpressed ornithine aminotransferase E Zigmond, AB Ya’acov, H Lee, Y Lichtenstein, Z Shalev, Y Smith, ... ACS Medicinal Chemistry Letters 6 (8), 840-844, 2015 | 48 | 2015 |
| PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation R Wu, R Sanishvili, BR Belitsky, JI Juncosa, HV Le, HJS Lehrer, M Farley, ... Proceedings of the National Academy of Sciences 114 (15), 3891-3896, 2017 | 34 | 2017 |
| Design and mechanism of tetrahydrothiophene-based γ-aminobutyric acid aminotransferase inactivators HV Le, DD Hawker, R Wu, E Doud, J Widom, R Sanishvili, D Liu, ... Journal of the American Chemical Society 137 (13), 4525-4533, 2015 | 33 | 2015 |
| Phytochemistry, Biological Activities, Therapeutic Potential, and Socio‐Economic Value of the Caper Bush (Capparis spinosa L.) A Kdimy, M El Yadini, A Guaadaoui, I Bourais, S El Hajjaji, HV Le Chemistry & Biodiversity 19, e202200300, 2022 | 25 | 2022 |
| A practical and inexpensive ‘convertible’isonitrile for use in multicomponent reactions HV Le, L Fan, B Ganem Tetrahedron Letters 52 (17), 2209-2211, 2011 | 24 | 2011 |
| A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse MIH Khan, BJ Sawyer, NS Akins, HV Le European Journal of Medicinal Chemistry 243, 114785, 2022 | 23 | 2022 |
| Selective targeting by a mechanism-based inactivator against pyridoxal 5′-phosphate-dependent enzymes: Mechanisms of inactivation and alternative turnover R Mascarenhas, HV Le, KD Clevenger, HJ Lehrer, D Ringe, NL Kelleher, ... Biochemistry 56 (37), 4951-4961, 2017 | 22 | 2017 |
| Mechanism of Inactivation of GABA Aminotransferase by (E)-and (Z)-(1 S, 3 S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid H Lee, HV Le, R Wu, E Doud, R Sanishvili, JF Kellie, PD Compton, ... ACS Chemical Biology 10 (9), 2087-2098, 2015 | 20 | 2015 |
| (S)-3-amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid, and related compounds as GABA aminotransferase inactivators for the treatment of epilepsy, addiction and … RB Silverman, K Takaya, HV Le, JI Juncosa US Patent 9,670,141, 2017 | 14 | 2017 |
| (S)-3-amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid, and related compounds as GABA aminotransferase inactivators for the treatment of epilepsy, addiction and … RB Silverman, K Takaya, HV Le, JI Juncosa US Patent 9,993,449, 2018 | 12 | 2018 |
| Inactivators of Toxoplasma gondii ornithine aminotransferase for treating toxoplasmosis and malaria RB Silverman, HV Le, RL McLeod, DD Hawker US Patent 10,632,088, 2020 | 9 | 2020 |
| (S)-3-Amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid, and Related Compounds as GABA Aminotransferase Inactivators for the Treatment of Epilepsy, Addiction and … RB Silverman, K Takaya, HV Le, JI Juncosa US Patent App. 15/991,323, 2018 | 9 | 2018 |
| Mild oxidation of tosylmethylisocyanide to tosylmethylisocyanate: utility in synthetic and medicinal chemistry HV Le, B Ganem Tetrahedron Letters 55 (12), 2003-2005, 2014 | 9 | 2014 |
| 6, 5‐Fused Ring, C2‐Salvinorin Ester, Dual Kappa and Mu Opioid Receptor Agonists as Analgesics Devoid of Anxiogenic Effects N Akins, N Mishra, H Harris, N Dudhipala, SJ Kim, A Keasling, ... ChemMedChem 17 (7), e202100684, 2022 | 7 | 2022 |
| A simple, general synthesis of carbonimidic dichlorides CM Gober, HV Le, B Ganem Tetrahedron Letters 53 (34), 4536-4537, 2012 | 7 | 2012 |
| Therapeutic Potential of Salvinorin A and Its Analogues in Various Neurological Disorders J Cichon, R Liu, HV Le Translational Perioperative and Pain Medicine 9 (2), 452-457, 2022 | 6 | 2022 |
| Synthesis of 3,4,5-trisubstituted isoxazoles in water via a [3 + 2]-cycloaddition of nitrile oxides and 1,3-diketones, β-ketoesters, or β-ketoamides MI Hossain, MIH Khan, SJ Kim, HV Le Beilstein Journal of Organic Chemistry 18, 446–458, 2022 | 6 | 2022 |
Dali LiuProfessor of Biochemistry, Loyola University Chicago在 luc.edu 的电子邮件经过验证
