m6A RNA methylation promotes XIST-mediated transcriptional repression DP Patil, CK Chen, BF Pickering, A Chow, C Jackson, M Guttman, ... Nature 537 (7620), 369-373, 2016 | 1493 | 2016 |
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3 CA McHugh, CK Chen, A Chow, CF Surka, C Tran, P McDonel, ... Nature 521 (7551), 232-236, 2015 | 1116 | 2015 |
Single-cell phenotyping within transparent intact tissue through whole-body clearing B Yang, JB Treweek, RP Kulkarni, BE Deverman, CK Chen, E Lubeck, ... Cell 158 (4), 945-958, 2014 | 1014 | 2014 |
Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing CK Chen, M Blanco, C Jackson, E Aznauryan, N Ollikainen, C Surka, ... Science 354 (6311), 468-472, 2016 | 298 | 2016 |
Structured elements drive extensive circular RNA translation CK Chen, R Cheng, J Demeter, J Chen, S Weingarten-Gabbay, L Jiang, ... Molecular cell 81 (20), 4300-4318. e13, 2021 | 148 | 2021 |
A protein assembly mediates Xist localization and gene silencing A Pandya-Jones, Y Markaki, J Serizay, T Chitiashvili, WR Mancia Leon, ... Nature 587 (7832), 145-151, 2020 | 139 | 2020 |
Engineering circular RNA for enhanced protein production R Chen, SK Wang, JA Belk, L Amaya, Z Li, A Cardenas, BT Abe, CK Chen, ... Nature biotechnology 41 (2), 262-272, 2023 | 122 | 2023 |
Activity-dependent facilitation of Synaptojanin and synaptic vesicle recycling by the Minibrain kinase CK Chen, C Bregere, J Paluch, JF Lu, DK Dickman, KT Chang Nature communications 5 (1), 4246, 2014 | 63 | 2014 |
The role of circular RNAs in pulmonary hypertension MK Ali, K Schimmel, L Zhao, CK Chen, K Dua, MR Nicolls, ... European Respiratory Journal 60 (6), 2022 | 22 | 2022 |
Phosphorylation of synaptojanin differentially regulates endocytosis of functionally distinct synaptic vesicle pools J Geng, L Wang, JY Lee, CK Chen, KT Chang Journal of Neuroscience 36 (34), 8882-8894, 2016 | 22 | 2016 |
Noncoding RNAs: biology and applications—a Keystone Symposia report J Cable, E Heard, T Hirose, KV Prasanth, LL Chen, JE Henninger, ... Annals of the new York Academy of Sciences 1506 (1), 118-141, 2021 | 15 | 2021 |
Response to Comment on “Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing” CK Chen, A Chow, M Lai, M Guttman Science 356 (6343), eaam5439, 2017 | 7 | 2017 |
An Xist-dependent protein assembly mediates Xist localization and gene silencing A Pandya-Jones, Y Markaki, J Serizay, T Chitiashvilli, W Mancia, ... BioRxiv, 2020.03. 09.979369, 2020 | 6 | 2020 |
Reactivation of x chromosome genes M Guttman, CK Chen, CA McHugh US Patent 11,249,071, 2022 | 5 | 2022 |
Reactivation of x chromosome genes M Guttman, CK Chen, CA McHugh US Patent App. 15/336,748, 2017 | 2 | 2017 |
Revealing the Mechanism of Xist-mediated Silencing CK Chen California Institute of Technology, 2018 | 1 | 2018 |
HDAC inhibitor compositions for reactivation of the X chromosome M Guttman, CK Chen US Patent 11,197,881, 2021 | | 2021 |
LBR IS REQUIRED FOR XIST SPREADING TO ACTIVELY TRANSCRIBED GENES ACROSS THE X-CHROMOSOME CK Chen Revealing the Mechanism of Xist-mediated Silencing, 71, 2017 | | 2017 |
Minibrain kinase enhances synaptojanin activity to facilitate endocytosis during synaptic activity CK Chen University of Southern California, 2015 | | 2015 |