Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations DK Williams, J Wang, RL Papke Biochemical pharmacology 82 (8), 915-930, 2011 | 310 | 2011 |
Investigation of the Molecular Mechanism of the α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator PNU-120596 Provides Evidence for Two Distinct Desensitized States DK Williams, J Wang, RL Papke Molecular Pharmacology 80 (6), 1013-1032, 2011 | 138* | 2011 |
Intrinsically low open probability of α7 nicotinic acetylcholine receptors can be overcome by positive allosteric modulation and serum factors leading to the generation of … DK Williams, C Peng, MR Kimbrell, RL Papke Molecular pharmacology 82 (4), 746-759, 2012 | 74* | 2012 |
The effective opening of nicotinic acetylcholine receptors with single agonist binding sites DK Williams, C Stokes, NA Horenstein, RL Papke Journal of General Physiology 137 (4), 369-384, 2011 | 63 | 2011 |
Development of repetitive behavior in a mouse model: roles of indirect and striosomal basal ganglia pathways Y Tanimura, MA King, DK Williams, MH Lewis International Journal of Developmental Neuroscience 29 (4), 461-467, 2011 | 60 | 2011 |
Differential regulation of receptor activation and agonist selectivity by highly conserved tryptophans in the nicotinic acetylcholine receptor binding site DK Williams, C Stokes, NA Horenstein, RL Papke Journal of Pharmacology and Experimental Therapeutics 330 (1), 40-53, 2009 | 35 | 2009 |
Cysteine accessibility analysis of the human alpha7 nicotinic acetylcholine receptor ligand-binding domain identifies L119 as a gatekeeper RL Papke, C Stokes, DK Williams, J Wang, NA Horenstein Neuropharmacology 60 (1), 159-171, 2011 | 34 | 2011 |
Pathogenesis and treatment of oral candidosis. J Oral Microbiol. 2011; 3: 5771 D Williams, M Lewis | 8 | |
Pathogenesis and treatment of oral candidosis. J Oral Microbiol 3: 1–12 D Williams, M Lewis | 4 | 2011 |
Positive and negative cooperativity of agonist and allosteric modulator binding in alpha7 nAChR: Looking for the therapeutic window RL Papke, DK Williams, J Wang, NA Horenstein Biochemical Pharmacology 8 (82), 1031, 2011 | | 2011 |