Interplay between MicroRNAs and oxidative stress in neurodegenerative diseases J Konovalova, D Gerasymchuk, I Parkkinen, P Chmielarz, A Domanskyi International journal of molecular sciences 20 (23), 6055, 2019 | 176 | 2019 |
Neuroprotective effects of pomegranate juice against Parkinson’s disease and presence of ellagitannins-derived metabolite—urolithin A—in the brain M Kujawska, M Jourdes, M Kurpik, M Szulc, H Szaefer, P Chmielarz, ... International journal of molecular sciences 21 (1), 202, 2019 | 136 | 2019 |
Dicer and microRNAs protect adult dopamine neurons P Chmielarz, J Konovalova, SS Najam, H Alter, TP Piepponen, H Erfle, ... Cell death & disease 8 (5), e2813-e2813, 2017 | 101 | 2017 |
Neurotrophic factors for disease-modifying treatments of Parkinson's disease: gaps between basic science and clinical studies P Chmielarz, M Saarma Pharmacological Reports 72, 1195-1217, 2020 | 62 | 2020 |
Back and to the future: from neurotoxin‐induced to human Parkinson's disease models M Airavaara, I Parkkinen, J Konovalova, K Albert, P Chmielarz, ... Current Protocols in Neuroscience 91 (1), e88, 2020 | 56 | 2020 |
Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects P Zajdel, T Kos, K Marciniec, G Satała, V Canale, K Kamiński, M Hołuj, ... European Journal of Medicinal Chemistry 145, 790-804, 2018 | 47 | 2018 |
GDNF/RET signaling pathway activation eliminates Lewy body pathology in midbrain dopamine neurons P Chmielarz, Ş Er, J Konovalova, L Bandres, I Hlushchuk, K Albert, ... Movement Disorders 35 (12), 2279-2289, 2020 | 45 | 2020 |
Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo K Albert, DP Raymundo, A Panhelainen, A Eesmaa, L Shvachiy, ... Molecular Therapy 29 (9), 2821-2840, 2021 | 35 | 2021 |
Inactivation of glucocorticoid receptor in noradrenergic system influences anxiety-and depressive-like behavior in mice P Chmielarz, J Kuśmierczyk, R Parlato, G Schütz, I Nalepa, G Kreiner PLoS One 8 (8), e72632, 2013 | 31 | 2013 |
MANF ablation causes prolonged activation of the UPR without neurodegeneration in the mouse midbrain dopamine system E Pakarinen, T Danilova, V Võikar, P Chmielarz, P Piepponen, ... ENeuro 7 (1), 2020 | 29 | 2020 |
Acute and repeated treatment with the 5-HT7 receptor antagonist SB 269970 induces functional desensitization of 5-HT7 receptors in rat hippocampus K Tokarski, A Zelek-Molik, B Duszyńska, G Satała, B Bobula, M Kusek, ... Pharmacological Reports 64 (2), 256-265, 2012 | 27 | 2012 |
Studying pre-formed fibril induced α-synuclein accumulation in primary embryonic mouse midbrain dopamine neurons S Er, I Hlushchuk, M Airavaara, P Chmielarz, A Domanskyi JoVE (Journal of Visualized Experiments), e61118, 2020 | 25 | 2020 |
Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism G Kreiner, K Rafa-Zabłocka, J Barut, P Chmielarz, M Kot, M Bagińska, ... Scientific reports 9 (1), 5262, 2019 | 25 | 2019 |
Gender differences in genetic mouse models evaluated for depressive-like and antidepressant behavior G Kreiner, P Chmielarz, A Roman, I Nalepa Pharmacological Reports 65 (6), 1580-1590, 2013 | 25 | 2013 |
Functionally distinctive Ptch receptors establish multimodal Hedgehog signaling in the tooth epithelial stem cell niche M Binder, P Chmielarz, PJ Mckinnon, LC Biggs, I Thesleff, A Balic Stem Cells 37 (9), 1238-1248, 2019 | 24 | 2019 |
Disruption of glucocorticoid receptors in the noradrenergic system leads to BDNF up-regulation and altered serotonergic transmission associated with a depressive-like phenotype … P Chmielarz, G Kreiner, M Kot, A Zelek-Molik, M Kowalska, M Bagińska, ... Pharmacology Biochemistry and Behavior 137, 69-77, 2015 | 15 | 2015 |
Depressive-like immobility behavior and genotype× stress interactions in male mice of selected strains P Chmielarz, G Kreiner, J Kuśmierczyk, M Kowalska, A Roman, K Tota, ... Stress 19 (2), 206-213, 2016 | 12 | 2016 |
Selective ablation of glucocorticoid receptors in the noradrenergic system affects evening corticosterone levels in a sex-dependent manner P Chmielarz, G Kreiner, I Nalepa Pharmacological Reports 67 (6), 1201-1203, 2015 | 11 | 2015 |
Alpha-synuclein preformed fibrils: a tool to understand Parkinson’s disease and develop disease modifying therapy P Chmielarz, A Domanskyi Neural regeneration research 16 (11), 2219-2221, 2021 | 10 | 2021 |
Chronic restraint stress induces changes in the cerebral Galpha 12/13 and Rho-GTPase signaling network K Rafa-Zabłocka, A Zelek-Molik, B Tepper, P Chmielarz, G Kreiner, ... Pharmacological Reports 73 (4), 1179-1187, 2021 | 5 | 2021 |