Neuronal injury mediated via stimulation of microglial toll‐like receptor‐9 (TLR9) AI Iliev, AK Stringaris, R Nau, H Neumann The FASEB Journal 18 (2), 1-17, 2004 | 205 | 2004 |
Amyloid beta peptide 1–40 enhances the action of Toll‐like receptor‐2 and‐4 agonists but antagonizes Toll‐like receptor‐9‐induced inflammation in primary mouse microglial cell … M Lotz, S Ebert, H Esselmann, AI Iliev, M Prinz, N Wiazewicz, J Wiltfang, ... Journal of neurochemistry 94 (2), 289-298, 2005 | 148 | 2005 |
Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin AI Iliev, JR Djannatian, R Nau, TJ Mitchell, FS Wouters Proceedings of the National Academy of Sciences 104 (8), 2897-2902, 2007 | 119 | 2007 |
Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide M Stagi, PS Dittrich, N Frank, AI Iliev, P Schwille, H Neumann Journal of Neuroscience 25 (2), 352-362, 2005 | 87 | 2005 |
Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage C Wippel, J Maurer, C Förtsch, S Hupp, A Bohl, J Ma, TJ Mitchell, ... PLoS pathogens 9 (6), e1003380, 2013 | 54 | 2013 |
Rapid microtubule bundling and stabilization by the Streptococcus pneumoniae neurotoxin pneumolysin in a cholesterol‐dependent, non‐lytic and Src‐kinase … AI Iliev, JR Djannatian, F Opazo, J Gerber, R Nau, TJ Mitchell, FS Wouters Molecular microbiology 71 (2), 461-477, 2009 | 47 | 2009 |
Direct transmembrane interaction between actin and the pore-competent, cholesterol-dependent cytolysin pneumolysin S Hupp, C Förtsch, C Wippel, J Ma, TJ Mitchell, AI Iliev Journal of molecular biology 425 (3), 636-646, 2013 | 41 | 2013 |
Removal of pattern-breaking sequences in microtubule binding repeats produces instantaneous tau aggregation and toxicity AI Iliev, S Ganesan, G Bunt, FS Wouters Journal of Biological Chemistry 281 (48), 37195-37204, 2006 | 38 | 2006 |
Effect of the acetylcholinesterase inhibitor galanthamine on learning and memory in prolonged alcohol intake rat model of acetylcholine deficit. A Iliev, V Traykov, D Prodanov, G Mantchev, K Yakimova, I Krushkov, ... Methods and findings in experimental and clinical pharmacology 21 (4), 297-301, 1999 | 36 | 1999 |
Quantitative fluorescence microscopy techniques A Esposito, S Schlachter, GSK Schierle, AD Elder, A Diaspro, FS Wouters, ... Cytoskeleton Methods and Protocols, 117-142, 2010 | 33 | 2010 |
Astrocytic tissue remodeling by the meningitis neurotoxin pneumolysin facilitates pathogen tissue penetration and produces interstitial brain edema S Hupp, V Heimeroth, C Wippel, C Förtsch, J Ma, TJ Mitchell, AI Iliev Glia 60 (1), 137-146, 2012 | 31 | 2012 |
Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity C Förtsch, S Hupp, J Ma, TJ Mitchell, E Maier, R Benz, AI Iliev Toxins 3 (1), 43-62, 2011 | 30 | 2011 |
Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue C Wippel, C Förtsch, S Hupp, E Maier, R Benz, J Ma, TJ Mitchell, AI Iliev Journal of Infectious Diseases 204 (6), 930-936, 2011 | 28 | 2011 |
A Post‐ischaemic Single Administration of Galanthamine, a Cholinesterase Inhibitor, Improves Learning Ability in Rats AI Iliev, VB Traykov, GT Mantchev, I Stoykov, D Prodanov, KS Yakimova, ... Journal of pharmacy and pharmacology 52 (9), 1151-1156, 2000 | 25 | 2000 |
Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia S Hupp, D Grandgirard, TJ Mitchell, SL Leib, LJ Hathaway, AI Iliev Journal of neuroinflammation 16, 1-14, 2019 | 21 | 2019 |
Effects of dexamethasone in rat neonatal model of axotomy-induced motoneuronal cell death D Prodanov, G Mantchev, A Iliev, V Traykov, K Yakimova, R Kaneva, ... Archives of physiology and biochemistry 106 (5), 355-361, 1998 | 19 | 1998 |
The inflammatory response and neuronal injury in Streptococcus suis meningitis J Seele, SC Tauber, S Bunkowski, CG Baums, P Valentin-Weigand, ... BMC infectious diseases 18, 1-9, 2018 | 18 | 2018 |
Pneumolysin boosts the neuroinflammatory response to Streptococcus pneumoniae through enhanced endocytosis S Hupp, C Förtsch, F Graber, TJ Mitchell, AI Iliev Nature communications 13 (1), 5032, 2022 | 17 | 2022 |
Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation S Hupp, S Ribes, J Seele, C Bischoff, C Förtsch, E Maier, R Benz, ... British journal of pharmacology 174 (23), 4295-4307, 2017 | 15 | 2017 |
Estradiol inhibits astrocytic GFAP expression in an animal model of neuroinflammation. A Iliev, V Traykov, I Stoykov, K Yakimova Methods and findings in experimental and clinical pharmacology 23 (1), 29-36, 2001 | 14 | 2001 |