Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling N Kayagaki, IB Stowe, BL Lee, K O’Rourke, K Anderson, S Warming, ... Nature 526 (7575), 666-671, 2015 | 3361 | 2015 |
Non-canonical inflammasome activation targets caspase-11 N Kayagaki, S Warming, M Lamkanfi, LV Walle, S Louie, J Dong, ... Nature 479 (7371), 117-121, 2011 | 2666 | 2011 |
Noncanonical inflammasome activation by intracellular LPS independent of TLR4 N Kayagaki, MT Wong, IB Stowe, SR Ramani, LC Gonzalez, ... Science 341 (6151), 1246-1249, 2013 | 1604 | 2013 |
IAP antagonists induce autoubiquitination of c-IAPs, NF-κB activation, and TNFα-dependent apoptosis E Varfolomeev, JW Blankenship, SM Wayson, AV Fedorova, N Kayagaki, ... Cell 131 (4), 669-681, 2007 | 1454 | 2007 |
Metalloproteinase-mediated release of human Fas ligand. N Kayagaki, A Kawasaki, T Ebata, H Ohmoto, S Ikeda, S Inoue, K Yoshino, ... The Journal of experimental medicine 182 (6), 1777-1783, 1995 | 1053 | 1995 |
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells K Takeda, Y Hayakawa, MJ Smyth, N Kayagaki, N Yamaguchi, S Kakuta, ... Nature medicine 7 (1), 94-100, 2001 | 991 | 2001 |
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes RA Aglietti, A Estevez, A Gupta, MG Ramirez, PS Liu, N Kayagaki, ... Proceedings of the National Academy of Sciences 113 (28), 7858-7863, 2016 | 869 | 2016 |
Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death P Orning, D Weng, K Starheim, D Ratner, Z Best, B Lee, A Brooks, S Xia, ... Science 362 (6418), 1064-1069, 2018 | 862 | 2018 |
Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) contributes to interferon γ–dependent natural killer cell protection from tumor metastasis MJ Smyth, E Cretney, K Takeda, RH Wiltrout, LM Sedger, N Kayagaki, ... The Journal of experimental medicine 193 (6), 661-670, 2001 | 675 | 2001 |
Critical role for tumor necrosis factor–related apoptosis-inducing ligand in immune surveillance against tumor development K Takeda, MJ Smyth, E Cretney, Y Hayakawa, N Kayagaki, H Yagita, ... The Journal of experimental medicine 195 (2), 161-169, 2002 | 632 | 2002 |
BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2 N Kayagaki, M Yan, D Seshasayee, H Wang, W Lee, DM French, ... Immunity 17 (4), 515-524, 2002 | 618 | 2002 |
Type I interferons (IFNs) regulate tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) expression on human T cells: a novel mechanism for the antitumor effects of … N Kayagaki, N Yamaguchi, M Nakayama, H Eto, K Okumura, H Yagita The Journal of experimental medicine 189 (9), 1451-1460, 1999 | 615 | 1999 |
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1 P Broz, T Ruby, K Belhocine, DM Bouley, N Kayagaki, VM Dixit, ... Nature 490 (7419), 288-291, 2012 | 610 | 2012 |
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis JW Jones, N Kayagaki, P Broz, T Henry, K Newton, K O'Rourke, S Chan, ... Proceedings of the National Academy of Sciences 107 (21), 9771-9776, 2010 | 590 | 2010 |
NINJ1 mediates plasma membrane rupture during lytic cell death N Kayagaki, OS Kornfeld, BL Lee, IB Stowe, K O’Rourke, Q Li, ... Nature 591 (7848), 131-136, 2021 | 536 | 2021 |
A deubiquitinase that regulates type I interferon production N Kayagaki, Q Phung, S Chan, R Chaudhari, C Quan, KM O'Rourke, ... Science 318 (5856), 1628-1632, 2007 | 536 | 2007 |
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases E Meunier, MS Dick, RF Dreier, N Schürmann, DK Broz, S Warming, ... Nature 509 (7500), 366-370, 2014 | 510 | 2014 |
Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells N Kayagaki, N Yamaguchi, M Nakayama, K Takeda, H Akiba, H Tsutsui, ... The Journal of Immunology 163 (4), 1906-1913, 1999 | 462 | 1999 |
Antitumor effect of locally produced CD95 ligand KI Seino, N Kayagaki, KO Okumura, H Yagita Nature medicine 3 (2), 165-170, 1997 | 394 | 1997 |
Antiviral response by natural killer cells through TRAIL gene induction by IFN–α/β K Sato, S Hida, H Takayanagi, T Yokochi, N Kayagaki, K Takeda, ... European journal of immunology 31 (11), 3138-3146, 2001 | 367 | 2001 |