Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex S Kajimura, P Seale, K Kubota, E Lunsford, JV Frangioni, SP Gygi, ... Nature 460 (7259), 1154-1158, 2009 | 894 | 2009 |
Open sandwich ELISA: a novel immunoassay based on the interchain interaction of antibody variable region H Ueda, K Tsumoto, K Kubota, E Suzuki, T Nagamune, H Nishimura, ... Nature Biotechnology 14 (13), 1714-1718, 1996 | 198 | 1996 |
Regulation of meiotic recombination via Mek1-mediated Rad54 phosphorylation H Niu, L Wan, V Busygina, YH Kwon, JA Allen, X Li, RC Kunz, K Kubota, ... Molecular cell 36 (3), 393-404, 2009 | 185 | 2009 |
Platelet‐derived growth factor BB secreted from osteoclasts acts as an osteoblastogenesis inhibitory factor K Kubota, C Sakikawa, M Katsumata, T Nakamura, K Wakabayashi Journal of Bone and Mineral Research 17 (2), 257-265, 2002 | 174 | 2002 |
Comparison of enzymatic properties between hPADI2 and hPADI4 M Nakayama-Hamada, A Suzuki, K Kubota, T Takazawa, M Ohsaka, ... Biochemical and biophysical research communications 327 (1), 192-200, 2005 | 138 | 2005 |
Sensitive multiplexed analysis of kinase activities and activity-based kinase identification K Kubota, R Anjum, Y Yu, RC Kunz, JN Andersen, M Kraus, H Keilhack, ... Nature biotechnology 27 (10), 933-940, 2009 | 123 | 2009 |
Proteome analysis of secreted proteins during osteoclast differentiation using two different methods: Two‐dimensional electrophoresis and isotope‐coded affinity tags analysis … K Kubota, K Wakabayashi, T Matsuoka Proteomics 3 (5), 616-626, 2003 | 114 | 2003 |
Identification of 2′-phosphodiesterase, which plays a role in the 2-5A system regulated by interferon K Kubota, K Nakahara, T Ohtsuka, S Yoshida, J Kawaguchi, Y Fujita, ... Journal of Biological Chemistry 279 (36), 37832-37841, 2004 | 110 | 2004 |
p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling Y Abe, SO Yoon, K Kubota, MC Mendoza, SP Gygi, J Blenis Journal of Biological Chemistry 284 (22), 14939-14948, 2009 | 109 | 2009 |
TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells SI Saitoh, F Abe, A Kanno, N Tanimura, Y Mori Saitoh, R Fukui, T Shibata, ... Nature communications 8 (1), 1592, 2017 | 99 | 2017 |
A site-specific, multiplexed kinase activity assay using stable-isotope dilution and high-resolution mass spectrometry Y Yu, R Anjum, K Kubota, J Rush, J Villen, SP Gygi Proceedings of the National Academy of Sciences 106 (28), 11606-11611, 2009 | 89 | 2009 |
Target deconvolution from phenotype-based drug discovery by using chemical proteomics approaches K Kubota, M Funabashi, Y Ogura Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (1), 22-27, 2019 | 82 | 2019 |
Human carboxymethylenebutenolidase as a bioactivating hydrolase of olmesartan medoxomil in liver and intestine T Ishizuka, I Fujimori, M Kato, C Noji-Sakikawa, M Saito, Y Yoshigae, ... Journal of Biological Chemistry 285 (16), 11892-11902, 2010 | 61 | 2010 |
Homogeneous noncompetitive immunoassay based on the energy transfer between fluorolabeled antibody variable domains (open sandwich fluoroimmunoassay) H Ueda, K Kubota, Y Wang, K Tsumoto, W Mahoney, I Kumagai, ... Biotechniques 27 (4), 738-742, 1999 | 61 | 1999 |
Identification of valproic acid glucuronide hydrolase as a key enzyme for the interaction of valproic acid with carbapenem antibiotics E Suzuki, N Yamamura, Y Ogura, D Nakai, K Kubota, N Kobayashi, ... Drug Metabolism and Disposition 38 (9), 1538-1544, 2010 | 53 | 2010 |
Determination of sites citrullinated by peptidylarginine deiminase using 18O stable isotope labeling and mass spectrometry K Kubota, T Yoneyama‐Takazawa, K Ichikawa Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005 | 52 | 2005 |
Proteomic comparison of the secreted factors of mesenchymal stem cells from bone marrow, adipose tissue and dental pulp Y Tachida, H Sakurai, J Okutsu Journal of Proteomics & Bioinformatics 8 (12), 2015 | 49 | 2015 |
Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling F Simeoni, L Tasselli, S Tanaka, L Villanova, M Hayashi, K Kubota, ... Scientific reports 3 (1), 3085, 2013 | 41 | 2013 |
Combination of two-dimensional electrophoresis and shotgun peptide sequencing in comparative proteomics K Kubota, T Kosaka, K Ichikawa Journal of Chromatography B 815 (1-2), 3-9, 2005 | 38 | 2005 |
IQGAP1 selectively interacts with K-Ras but not with H-Ras and modulates K-Ras function H Matsunaga, K Kubota, T Inoue, F Isono, O Ando Biochemical and biophysical research communications 444 (3), 360-364, 2014 | 32 | 2014 |