| Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome D Colak, N Zaninovic, MS Cohen, Z Rosenwaks, WY Yang, J Gerhardt, ... Science 343 (6174), 1002-1005, 2014 | 316 | 2014 |
| FANCD2 facilitates replication through common fragile sites A Madireddy, ST Kosiyatrakul, RA Boisvert, E Herrera-Moyano, ... Molecular cell 64 (2), 388-404, 2016 | 184 | 2016 |
| Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus M Ritzi, K Tillack, J Gerhardt, E Ott, S Humme, E Kremmer, ... Journal of cell science 116 (19), 3971-3984, 2003 | 133 | 2003 |
| Ataxia telangiectasia-mutated damage-signaling kinase-and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in Simian virus 40-infected primate cells X Zhao, RJ Madden-Fuentes, BX Lou, JM Pipas, J Gerhardt, CJ Rigell, ... Journal of virology 82 (11), 5316-5328, 2008 | 127 | 2008 |
| The DNA replication program is altered at the FMR1 locus in fragile X embryonic stem cells J Gerhardt, MJ Tomishima, N Zaninovic, D Colak, Z Yan, Q Zhan, ... Molecular cell 53 (1), 19-31, 2014 | 99 | 2014 |
| Gynecological cancers caused by deficient mismatch repair and microsatellite instability M Deshpande, PA Romanski, Z Rosenwaks, J Gerhardt Cancers 12 (11), 3319, 2020 | 72 | 2020 |
| Fragile X-associated diminished ovarian reserve and primary ovarian insufficiency from molecular mechanisms to clinical manifestations L Man, J Lekovich, Z Rosenwaks, J Gerhardt Frontiers in molecular neuroscience 10, 290, 2017 | 65 | 2017 |
| Stalled DNA replication forks at the endogenous GAA repeats drive repeat expansion in Friedreich’s ataxia cells J Gerhardt, AD Bhalla, JS Butler, JW Puckett, PB Dervan, Z Rosenwaks, ... Cell reports 16 (5), 1218-1227, 2016 | 57 | 2016 |
| Identification of new human origins of DNA replication by an origin-trapping assay J Gerhardt, S Jafar, MP Spindler, E Ott, A Schepers Molecular and cellular biology, 2006 | 54 | 2006 |
| An origin of DNA replication in the promoter region of the human fragile X mental retardation (FMR1) gene SJ Gray, J Gerhardt, W Doerfler, LE Small, E Fanning Molecular and cellular biology, 2007 | 53 | 2007 |
| Cis-acting DNA sequence at a replication origin promotes repeat expansion to fragile X full mutation J Gerhardt, N Zaninovic, Q Zhan, A Madireddy, SL Nolin, N Ersalesi, ... Journal of Cell Biology 206 (5), 599-607, 2014 | 42 | 2014 |
| The genetic architecture of DNA replication timing in human pluripotent stem cells Q Ding, MM Edwards, N Wang, X Zhu, AN Bracci, ML Hulke, Y Hu, Y Tong, ... Nature communications 12 (1), 6746, 2021 | 39 | 2021 |
| Replication through repetitive DNA elements and their role in human diseases A Madireddy, J Gerhardt DNA Replication: From Old Principles to New Discoveries, 549-581, 2017 | 33 | 2017 |
| High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster S Jasra, O Giricz, R Zeig-Owens, K Pradhan, DG Goldfarb, ... Nature medicine 28 (3), 468-471, 2022 | 26 | 2022 |
| CGG repeat length and AGG interruptions as indicators of fragile X–associated diminished ovarian reserve J Lekovich, L Man, K Xu, C Canon, D Lilienthal, JD Stewart, N Pereira, ... Genetics in Medicine 20 (9), 957-964, 2018 | 24 | 2018 |
| Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin J Gerhardt, GD Guler, E Fanning Experimental cell research 334 (2), 283-293, 2015 | 23 | 2015 |
| Pluripotent stem cells with low differentiation potential contain incompletely reprogrammed DNA replication T Paniza, M Deshpande, N Wang, R O’Neil, MV Zuccaro, ME Smith, ... Journal of Cell Biology 219 (9), e201909163, 2020 | 14 | 2020 |
| LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components Y Fan, MS Köberlin, N Ratnayeke, C Liu, M Deshpande, J Gerhardt, ... Journal of Cell Biology 220 (8), e202009147, 2021 | 13 | 2021 |
| Epigenetic modifications in human fragile X pluripotent stem cells; Implications in fragile X syndrome modeling J Gerhardt Brain research 1656, 55-62, 2017 | 13 | 2017 |
| Notch hyper-activation drives trans-differentiation of hESC-derived endothelium D Reichman, L Man, L Park, R Lis, J Gerhardt, Z Rosenwaks, D James Stem cell research 17 (2), 391-400, 2016 | 13 | 2016 |
