A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging W Zhang, J Li, K Suzuki, J Qu, P Wang, J Zhou, X Liu, R Ren, X Xu, ... Science 348 (6239), 1160-1163, 2015 | 527 | 2015 |
Repression of the antioxidant NRF2 pathway in premature aging N Kubben, W Zhang, L Wang, TC Voss, J Yang, J Qu, GH Liu, T Misteli Cell 165 (6), 1361-1374, 2016 | 469 | 2016 |
SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2 H Pan, D Guan, X Liu, J Li, L Wang, J Wu, J Zhou, W Zhang, R Ren, ... Cell research 26 (2), 190-205, 2016 | 314 | 2016 |
PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype S Duan, G Yuan, X Liu, R Ren, J Li, W Zhang, J Wu, X Xu, L Fu, Y Li, ... Nature communications 6 (1), 10068, 2015 | 158 | 2015 |
Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7 J Fang, J Yang, X Wu, G Zhang, T Li, X Wang, H Zhang, C Wang, GH Liu, ... Aging cell 17 (4), e12765, 2018 | 148 | 2018 |
CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs L Wang, F Yi, L Fu, J Yang, S Wang, Z Wang, K Suzuki, L Sun, X Xu, Y Yu, ... Protein & Cell 8 (5), 365-378, 2017 | 118 | 2017 |
Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding J Yang, J Li, K Suzuki, X Liu, J Wu, W Zhang, R Ren, W Zhang, P Chan, ... Cell research 27 (9), 1178-1181, 2017 | 56 | 2017 |
Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs L Fu, X Xu, R Ren, J Wu, W Zhang, J Yang, X Ren, S Wang, Y Zhao, ... Protein & cell 7 (3), 210-221, 2016 | 41 | 2016 |
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ... The EMBO Journal 41 (21), e110393, 2022 | 30 | 2022 |
Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes Y Gu, GH Liu, N Plongthongkum, C Benner, F Yi, J Qu, K Suzuki, J Yang, ... Protein & cell 5 (1), 59-68, 2014 | 29 | 2014 |
Gating pluripotency via nuclear pores J Yang, N Cai, F Yi, GH Liu, J Qu, JCI Belmonte Trends in molecular medicine 20 (1), 1-7, 2014 | 22 | 2014 |
A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation SS Kim, AD Hudgins, J Yang, Y Zhu, Z Tu, MG Rosenfeld, TP DiLorenzo, ... PLoS One 16 (9), e0257265, 2021 | 17 | 2021 |
Direct reprogramming of porcine fibroblasts to neural progenitor cells XL Xu, JP Yang, LN Fu, RT Ren, F Yi, K Suzuki, K Liu, ZC Ding, J Qu, ... Protein & cell 5, 4-7, 2014 | 13 | 2014 |
Higher-order genomic organization in pluripotent stem cells P Wang, W Zhang, J Yang, J Qu, GH Liu Protein & cell 3 (7), 483-486, 2012 | 3 | 2012 |
The regulation of Insulin/IGF-1 signaling by miR-142-3p associated with human longevity X Wang, HJ Jung, B Milholland, J Cui, C Tazearslan, G Atzmon, X Wang, ... bioRxiv, 2023.05. 19.541542, 2023 | | 2023 |
Longevity-associated SMAD3 non-coding centenarian variant impairs a cell-type specific enhancer to reduce inflammation J Yang, A Tare, L Zhang, S Kim, S Ryu, Q Guo, Y Zhu, X Wang, X Wang, ... bioRxiv, 2023.05. 17.540984, 2023 | | 2023 |
iPSC Disease Modeling of Laminopathies GH Liu, J Yang, Z Ding, A Ocampo, J Qu, K Suzuki, JCI Belmonte Human iPS Cells in Disease Modelling, 53-67, 2016 | | 2016 |