| Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics I Irrcher, H Aleyasin, EL Seifert, SJ Hewitt, S Chhabra, M Phillips, AK Lutz, ... Human molecular genetics 19 (19), 3734-3746, 2010 | 461 | 2010 |
| Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease D Qu, J Rashidian*, MP Mount*, H Aleyasin*, M Parsanejad, A Lira, ... Neuron 55 (1), 37-52, 2007 | 281 | 2007 |
| The role of TDP-43 mislocalization in amyotrophic lateral sclerosis TR Suk, MWC Rousseaux Molecular neurodegeneration 15 (1), 45, 2020 | 275 | 2020 |
| DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway H Aleyasin*, MWC Rousseaux*, PC Marcogliese, SJ Hewitt, I Irrcher, ... Proceedings of the National Academy of Sciences, 200914876, 2010 | 200 | 2010 |
| The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage H Aleyasin, MWC Rousseaux, M Phillips, RH Kim, RJ Bland, S Callaghan, ... Proceedings of the National Academy of Sciences 104 (47), 18748-18753, 2007 | 186 | 2007 |
| Reduction of Nuak1 decreases tau and reverses phenotypes in a tauopathy mouse model CA Lasagna-Reeves, M de Haro, S Hao, J Park, MWC Rousseaux, ... Neuron 92 (2), 407-418, 2016 | 151 | 2016 |
| Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans HC Lu*, Q Tan*, MWC Rousseaux, W Wang, JY Kim, R Richman, ... Nature genetics 49 (4), 527, 2017 | 137 | 2017 |
| The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death E Huang*, D Qu*, Y Zhang, K Venderova, ME Haque, MWC Rousseaux, ... Nature cell biology 12 (6), 563, 2010 | 128 | 2010 |
| TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau MWC Rousseaux, M de Haro, CA Lasagna-Reeves, A De Maio, J Park, ... elife 5, e19809, 2016 | 111 | 2016 |
| ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism MWC Rousseaux*, T Tschumperlin*, HC Lu*, EP Lackey, VV Bondar, ... Neuron 97 (6), 1235-1243. e5, 2018 | 108 | 2018 |
| Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease MWC Rousseaux, PC Marcogliese, D Qu, SJ Hewitt, S Seang, RH Kim, ... Proceedings of the National Academy of Sciences 109 (39), 15918-15923, 2012 | 101 | 2012 |
| Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo J Rashidian, MW Rousseaux, K Venderova, D Qu, SM Callaghan, ... Journal of Neuroscience 29 (40), 12497-12505, 2009 | 88 | 2009 |
| An anatomically resolved mouse brain proteome reveals parkinson disease-relevant pathways SY Jung*, JM Choi*, MWC Rousseaux*, A Malovannaya, JJ Kim, ... Molecular & Cellular Proteomics, mcp. M116. 061440, 2017 | 61 | 2017 |
| BAG2 gene-mediated regulation of PINK1 protein is critical for mitochondrial translocation of PARKIN and neuronal survival D Qu, A Hage, K Don-Carolis, E Huang, A Joselin, F Safarpour, ... Journal of Biological Chemistry 290 (51), 30441-30452, 2015 | 60 | 2015 |
| A druggable genome screen identifies modifiers of α-synuclein levels via a tiered cross-species validation approach MWC Rousseaux*, GE Vázquez-Vélez*, I Al-Ramahi, HH Jeong, A Bajić, ... Journal of Neuroscience 38 (43), 9286-9301, 2018 | 52 | 2018 |
| DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress M Parsanejad, N Bourquard, D Qu, Y Zhang, E Huang, MWC Rousseaux, ... PLoS One 9 (9), e106601, 2014 | 52 | 2014 |
| Regulation of the VHL/HIF-1 pathway by DJ-1 M Parsanejad, Y Zhang, D Qu, I Irrcher, MWC Rousseaux, H Aleyasin, ... Journal of Neuroscience 34 (23), 8043-8050, 2014 | 52 | 2014 |
| Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma Q Tan, L Brunetti, MWC Rousseaux, HC Lu, YW Wan, JP Revelli, Z Liu, ... Proceedings of the National Academy of Sciences 115 (7), E1511-E1519, 2018 | 50 | 2018 |
| Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau MWC Rousseaux, JP Revelli, GE Vázquez-Vélez, JY Kim, E Craigen, ... Elife 7, e36768, 2018 | 48 | 2018 |
| Beta-binomial modeling of CRISPR pooled screen data identifies target genes with greater sensitivity and fewer false negatives HH Jeong, SY Kim, MWC Rousseaux, HY Zoghbi, Z Liu Genome research 29 (6), 999-1008, 2019 | 42 | 2019 |
Ruth SlackUniversity of Ottawa在 uottawa.ca 的电子邮件经过验证
