Identification of histone demethylases in Saccharomyces cerevisiae S Tu, EMM Bulloch, L Yang, C Ren, WC Huang, PH Hsu, CH Chen, ... Journal of Biological Chemistry 282 (19), 14262-14271, 2007 | 164 | 2007 |
Structure and function of GlmU from Mycobacterium tuberculosis Z Zhang, EMM Bulloch, RD Bunker, EN Baker, CJ Squire Acta Crystallographica Section D: Biological Crystallography 65 (3), 275-283, 2009 | 88 | 2009 |
Hydrolysis of the 5‘-p-Nitrophenyl Ester of TMP by the Proofreading Exonuclease (ε) Subunit of Escherichia coli DNA Polymerase III S Hamdan, EM Bulloch, PR Thompson, JL Beck, JY Yang, JA Crowther, ... Biochemistry 41 (16), 5266-5275, 2002 | 74 | 2002 |
Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI) A Manos‐Turvey, EMM Bulloch, PJ Rutledge, EN Baker, JS Lott, ... ChemMedChem 5 (7), 1067-1079, 2010 | 65 | 2010 |
The TB structural genomics consortium: a decade of progress N Chim, JE Habel, JM Johnston, I Krieger, L Miallau, ... Tuberculosis 91 (2), 155-172, 2011 | 62 | 2011 |
Transient dimerization of human MxA promotes GTP hydrolysis, resulting in a mechanical power stroke ML Rennie, SA McKelvie, EMM Bulloch, RL Kingston Structure 22 (10), 1433-1445, 2014 | 56 | 2014 |
Mechanistic and inhibition studies of chorismate-utilizing enzymes O Kerbarh, EMM Bulloch, RJ Payne, T Sahr, F Rébeillé, C Abell Biochemical Society Transactions 33 (4), 763-766, 2005 | 51 | 2005 |
Identification of 4-Amino-4-deoxychorismate Synthase as the Molecular Target for the Antimicrobial Action of (6S)-6-Fluoroshikimate EMM Bulloch, MA Jones, EJ Parker, AP Osborne, E Stephens, GM Davies, ... Journal of the American Chemical Society 126 (32), 9912-9913, 2004 | 49 | 2004 |
Implications of Binding Mode and Active Site Flexibility for Inhibitor Potency against the Salicylate Synthase from Mycobacterium tuberculosis G Chi, A Manos-Turvey, PD O’Connor, JM Johnston, GL Evans, EN Baker, ... Biochemistry 51 (24), 4868-4879, 2012 | 46 | 2012 |
Protein domain definition should allow for conditional disorder K Yegambaram, EMM Bulloch, RL Kingston Protein Science 22 (11), 1502-1518, 2013 | 40 | 2013 |
Advances in menaquinone biosynthesis: sublocalisation and allosteric regulation JM Johnston, EMM Bulloch Current opinion in structural biology 65, 33-41, 2020 | 36 | 2020 |
Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism RD Bunker, EMM Bulloch, JMJ Dickson, KM Loomes, EN Baker Journal of Biological Chemistry 288 (3), 1643-1652, 2013 | 32 | 2013 |
Design and synthesis of aromatic inhibitors of anthranilate synthase RJ Payne, MD Toscano, EMM Bulloch, AD Abell, C Abell Organic & biomolecular chemistry 3 (12), 2271-2281, 2005 | 32 | 2005 |
Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms ENM Jirgis, G Bashiri, EMM Bulloch, JM Johnston, EN Baker Structure 24 (7), 1167-1177, 2016 | 30 | 2016 |
Synthesis and evaluation of 2, 5-dihydrochorismate analogues as inhibitors of the chorismate-utilising enzymes RJ Payne, EMM Bulloch, MM Toscano, MA Jones, O Kerbarh, C Abell Organic & biomolecular chemistry 7 (11), 2421-2429, 2009 | 28 | 2009 |
The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition A Castell, FL Short, GL Evans, TVM Cookson, EMM Bulloch, DDA Joseph, ... Biochemistry 52 (10), 1776-1787, 2013 | 27 | 2013 |
Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis TVM Cookson, A Castell, EMM Bulloch, GL Evans, FL Short, EN Baker, ... Biochemical Journal 461 (1), 87-98, 2014 | 25 | 2014 |
Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex G Bashiri, JM Johnston, GL Evans, EMM Bulloch, DC Goldstone, ... Acta Crystallographica Section D: Biological Crystallography 71 (11), 2297-2308, 2015 | 24 | 2015 |
Repurposing the Chemical Scaffold of the Anti‐Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis GL Evans, SA Gamage, EMM Bulloch, EN Baker, WA Denny, JS Lott ChemBioChem 15 (6), 852-864, 2014 | 24 | 2014 |
Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site A Manos-Turvey, KM Cergol, NK Salam, EMM Bulloch, G Chi, A Pang, ... Organic & biomolecular chemistry 10 (46), 9223-9236, 2012 | 24 | 2012 |