The current treatment paradigm for pancreatic ductal adenocarcinoma and barriers to therapeutic efficacy DR Principe, PW Underwood, M Korc, JG Trevino, HG Munshi, A Rana Frontiers in oncology 11, 688377, 2021 | 143 | 2021 |
Long-term gemcitabine treatment reshapes the pancreatic tumor microenvironment and sensitizes murine carcinoma to combination immunotherapy DR Principe, M Narbutis, S Kumar, A Park, N Viswakarma, MJ Dorman, ... Cancer research 80 (15), 3101-3115, 2020 | 90 | 2020 |
Dorsal muscle group area and surgical outcomes in liver transplantation CS Lee, DC Cron, MN Terjimanian, LD Canvasser, AA Mazurek, ... Clinical transplantation 28 (10), 1092-1098, 2014 | 71 | 2014 |
Dual farnesyl and geranylgeranyl transferase inhibitor thwarts mutant KRAS-driven patient-derived pancreatic tumors A Kazi, S Xiang, H Yang, L Chen, P Kennedy, M Ayaz, S Fletcher, ... Clinical Cancer Research 25 (19), 5984-5996, 2019 | 65 | 2019 |
Sarcopenia and failure to rescue following liver transplantation PW Underwood, DC Cron, MN Terjimanian, SC Wang, MJ Englesbe, ... Clinical transplantation 29 (12), 1076-1080, 2015 | 51 | 2015 |
Cytotoxic effects of gemcitabine-loaded solid lipid nanoparticles in pancreatic cancer cells KO Affram, T Smith, E Ofori, S Krishnan, P Underwood, JG Trevino, ... Journal of drug delivery science and technology 55, 101374, 2020 | 47 | 2020 |
Postoperative surgical trainee opioid prescribing practices (POST OPP): an institutional study KR Olsen, DJ Hall, JC Mira, PW Underwood, AB Antony, T Vasilopoulos, ... journal of surgical research 229, 58-65, 2018 | 40 | 2018 |
Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL–Specific Degrader DT2216 D Thummuri, S Khan, PW Underwood, P Zhang, J Wiegand, X Zhang, ... Molecular cancer therapeutics 21 (1), 184-192, 2022 | 38 | 2022 |
Preclinical models of pancreatic ductal adenocarcinoma and their utility in immunotherapy studies TND Pham, MA Shields, C Spaulding, DR Principe, B Li, PW Underwood, ... Cancers 13 (3), 440, 2021 | 34 | 2021 |
MEF2c-dependent downregulation of myocilin mediates cancer-induced muscle wasting and associates with cachexia in patients with cancer SM Judge, MR Deyhle, D Neyroud, RL Nosacka, AC D'Lugos, ... Cancer research 80 (9), 1861-1874, 2020 | 32 | 2020 |
Cigarette smoking in living kidney donors: donor and recipient outcomes PW Underwood, KH Sheetz, DC Cron, MN Terjimanian, MJ Englesbe, ... Clinical Transplantation 28 (4), 419-422, 2014 | 30 | 2014 |
Global phosphoproteomics reveal CDK suppression as a vulnerability to KRas addiction in pancreatic cancer A Kazi, L Chen, S Xiang, R Vangipurapu, H Yang, F Beato, B Fang, ... Clinical Cancer Research 27 (14), 4012-4024, 2021 | 28 | 2021 |
The proteome of pancreatic cancer‐derived exosomes reveals signatures rich in key signaling pathways S Han, Z Huo, K Nguyen, F Zhu, PW Underwood, KBG Basso, TJ George, ... Proteomics 19 (13), 1800394, 2019 | 25 | 2019 |
XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer DR Principe, R Xiong, Y Li, TND Pham, SD Kamath, O Dubrovskyi, ... Proceedings of the National Academy of Sciences 119 (4), e2116764119, 2022 | 23 | 2022 |
Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer DR Principe, AF Aissa, S Kumar, TND Pham, PW Underwood, R Nair, ... Proceedings of the National Academy of Sciences 119 (18), e2200143119, 2022 | 22 | 2022 |
Loss of SMAD4 is associated with poor tumor immunogenicity and reduced PD-L1 expression in pancreatic cancer DR Principe, PW Underwood, S Kumar, KE Timbers, RM Koch, ... Frontiers in oncology 12, 806963, 2022 | 19 | 2022 |
Nicotine induces IL-8 secretion from pancreatic cancer stroma and worsens cancer-induced cachexia PW Underwood, DY Zhang, ME Cameron, MH Gerber, D Delitto, ... Cancers 12 (2), 329, 2020 | 19 | 2020 |
Local and systemic cytokine profiling for pancreatic ductal adenocarcinoma to study cancer cachexia in an era of precision medicine MH Gerber, PW Underwood, SM Judge, D Delitto, AE Delitto, RL Nosacka, ... International Journal of Molecular Sciences 19 (12), 3836, 2018 | 19 | 2018 |
The interleukin-1 axis and the tumor immune microenvironment in pancreatic ductal adenocarcinoma KM Herremans, DD Szymkiewicz, AN Riner, RP Bohan, GW Tushoski, ... Neoplasia 28, 100789, 2022 | 17 | 2022 |
Disparities in pancreatic ductal adenocarcinoma—the significance of Hispanic ethnicity, subgroup analysis, and treatment facility on clinical outcomes AN Riner, PW Underwood, K Yang, KM Herremans, ME Cameron, ... Cancer Medicine 9 (12), 4069-4082, 2020 | 16 | 2020 |