Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors Z Jin, X Du, Y Xu, Y Deng, M Liu, Y Zhao, B Zhang, X Li, L Zhang, C Peng, ... Nature 582 (7811), 289-293, 2020 | 3987 | 2020 |
Three-dimensional structure of the tyrosine kinase c-Src W Xu, SC Harrison, MJ Eck Nature 385 (6617), 595-602, 1997 | 1889 | 1997 |
Structure of the RNA-dependent RNA polymerase from COVID-19 virus Y Gao, L Yan, Y Huang, F Liu, Y Zhao, L Cao, T Wang, Q Sun, Z Ming, ... Science 368 (6492), 779-782, 2020 | 1657 | 2020 |
Crystal structures of c-Src reveal features of its autoinhibitory mechanism W Xu, A Doshi, M Lei, MJ Eck, SC Harrison Molecular cell 3 (5), 629-638, 1999 | 1112 | 1999 |
Recognition of antimicrobial peptides by a bacterial sensor kinase MW Bader, S Sanowar, ME Daley, AR Schneider, U Cho, W Xu, RE Klevit, ... Cell 122 (3), 461-472, 2005 | 668 | 2005 |
β-Catenin destruction complex: insights and questions from a structural perspective D Kimelman, W Xu Oncogene 25 (57), 7482-7491, 2006 | 627 | 2006 |
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme US Cho, W Xu Nature 445 (7123), 53-57, 2007 | 565 | 2007 |
Crystal structure of a β-catenin/Tcf complex TA Graham, C Weaver, F Mao, D Kimelman, W Xu Cell 103 (6), 885-896, 2000 | 546 | 2000 |
Structural basis for RNA replication by the SARS-CoV-2 polymerase Q Wang, J Wu, H Wang, Y Gao, Q Liu, A Mu, W Ji, L Yan, Y Zhu, C Zhu, ... Cell 182 (2), 417-428. e13, 2020 | 450 | 2020 |
Crystal structure of a paired domain-DNA complex at 2.5 Å resolution reveals structural basis for Pax developmental mutations W Xu, MA Rould, S Jun, C Desplan, CO Pabo Cell 80 (4), 639-650, 1995 | 410 | 1995 |
Crystal structure of a β-catenin/axin complex suggests a mechanism for the β-catenin destruction complex Y Xing, WK Clements, D Kimelman, W Xu Genes & development 17 (22), 2753-2764, 2003 | 359 | 2003 |
Crystal structure of the human Pax6 paired domain–DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding HE Xu, MA Rould, W Xu, JA Epstein, RL Maas, CO Pabo Genes & development 13 (10), 1263-1275, 1999 | 335 | 1999 |
Mechanistic insights from structural studies of β-catenin and its binding partners W Xu, D Kimelman Journal of cell science 120 (19), 3337-3344, 2007 | 316 | 2007 |
Recognition of the iso-ADP-ribose moiety in poly (ADP-ribose) by WWE domains suggests a general mechanism for poly (ADP-ribosyl) ation-dependent ubiquitination Z Wang, GA Michaud, Z Cheng, Y Zhang, TR Hinds, E Fan, F Cong, W Xu Genes & development 26 (3), 235-240, 2012 | 277 | 2012 |
Crystal structure of a full-length β-catenin Y Xing, KI Takemaru, J Liu, JD Berndt, JJ Zheng, RT Moon, W Xu Structure 16 (3), 478-487, 2008 | 277 | 2008 |
MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex TL Cheng, Z Wang, Q Liao, Y Zhu, WH Zhou, W Xu, Z Qiu Developmental cell 28 (5), 547-560, 2014 | 268 | 2014 |
Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling K Takada, D Zhu, GH Bird, K Sukhdeo, JJ Zhao, M Mani, M Lemieux, ... Science translational medicine 4 (148), 148ra117-148ra117, 2012 | 268 | 2012 |
Crystal structure of a β-catenin/BCL9/Tcf4 complex J Sampietro, CL Dahlberg, US Cho, TR Hinds, D Kimelman, W Xu Molecular cell 24 (2), 293-300, 2006 | 252 | 2006 |
Structure and function of the PP2A-shugoshin interaction Z Xu, B Cetin, M Anger, US Cho, W Helmhart, K Nasmyth, W Xu Molecular cell 35 (4), 426-441, 2009 | 249 | 2009 |
Tcf4 can specifically recognize β-catenin using alternative conformations TA Graham, DM Ferkey, F Mao, D Kimelman, W Xu Nature structural biology 8 (12), 1048-1052, 2001 | 220 | 2001 |