The bone microenvironment invigorates metastatic seeds for further dissemination W Zhang, IL Bado, J Hu, YW Wan, L Wu, H Wang, Y Gao, HH Jeong, Z Xu, ... Cell 184 (9), 2471-2486. e20, 2021 | 161 | 2021 |
Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis H Gu, C Chen, X Hao, C Wang, X Zhang, Z Li, H Shao, H Zeng, Z Yu, ... The Journal of Clinical Investigation 126 (12), 4537-4553, 2016 | 83 | 2016 |
PPM1K regulates hematopoiesis and leukemogenesis through CDC20-mediated ubiquitination of MEIS1 and p21 X Liu, F Zhang, Y Zhang, X Li, C Chen, M Zhou, Z Yu, Y Liu, Y Zhao, ... Cell reports 23 (5), 1461-1475, 2018 | 62 | 2018 |
Metabolic imaging reveals a unique preference of symmetric cell division and homing of leukemia-initiating cells in an endosteal niche X Hao, H Gu, C Chen, D Huang, Y Zhao, L Xie, Y Zou, HS Shu, Y Zhang, ... Cell Metabolism 29 (4), 950-965. e6, 2019 | 54 | 2019 |
JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/β-catenin/CCND1 signaling Y Zhang, F Xia, X Liu, Z Yu, L Xie, L Liu, C Chen, H Jiang, X Hao, X He, ... The Journal of Clinical Investigation 128 (5), 1737-1751, 2018 | 43 | 2018 |
ANGPTL2-containing small extracellular vesicles from vascular endothelial cells accelerate leukemia progression D Huang, G Sun, X Hao, X He, Z Zheng, C Chen, Z Yu, L Xie, S Ma, L Liu, ... The Journal of clinical investigation 131 (1), 2021 | 41 | 2021 |
Oxidative phosphorylation enhances the leukemogenic capacity and resistance to chemotherapy of B cell acute lymphoblastic leukemia C Chen, X Hao, X Lai, L Liu, J Zhu, H Shao, D Huang, H Gu, T Zhang, ... Science advances 7 (11), eabd6280, 2021 | 36 | 2021 |
Exploiting bone niches: progression of disseminated tumor cells to metastasis AM Muscarella, S Aguirre, X Hao, SM Waldvogel, XHF Zhang The Journal of Clinical Investigation 131 (6), 2021 | 25 | 2021 |
MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells H Gu, C Chen, X Hao, N Su, D Huang, Y Zou, SH Lin, X Chen, D Zheng, ... Blood, The Journal of the American Society of Hematology 136 (5), 553-571, 2020 | 21 | 2020 |
Luteinizing hormone signaling restricts hematopoietic stem cell expansion during puberty YJ Peng, H Yu, X Hao, W Dong, X Yin, M Lin, J Zheng, BO Zhou The EMBO Journal 37 (17), e98984, 2018 | 18 | 2018 |
Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal X Hao, Y Shen, N Chen, W Zhang, E Valverde, L Wu, HL Chan, Z Xu, L Yu, ... Cell stem cell 30 (5), 648-664. e8, 2023 | 12 | 2023 |
Bone Metastasis Initiation Is Coupled with Bone Remodeling through Osteogenic Differentiation of NG2+ Cells W Zhang, Z Xu, X Hao, T He, J Li, Y Shen, K Liu, Y Gao, J Liu, ... Cancer discovery 13 (2), 474-495, 2023 | 12 | 2023 |
Metabolic regulations in hematopoietic stem cells D Huang, C Chen, X Hao, H Gu, L Xie, Z Yu, J Zheng Leukemia Stem Cells in Hematologic Malignancies, 59-74, 2019 | 4 | 2019 |
BIGH3 mediates apoptosis and gap junction failure in osteocytes during renal cell carcinoma bone metastasis progression T Pan, F Liu, X Hao, S Wang, M Wasi, JH Song, VO Lewis, PP Lin, ... Cancer Letters, 217009, 2024 | | 2024 |
CBP/P300 BRD Inhibition Reduces Neutrophil Accumulation and Activates Antitumor Immunity in TNBC X Yuan, X Hao, HL Chan, N Zhao, DA Pedroza, F Liu, K Le, AJ Smith, ... bioRxiv, 2024 | | 2024 |
Single cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization. F Liu, Y Ding, Z Xu, X Hao, T Pan, G Miles, CH Rivas, D Hoffman, ... bioRxiv, 2024.05. 07.593027, 2024 | | 2024 |
Unbiased metastatic niche-labeling identifies estrogen receptor-positive macrophages as a barrier of T cell infiltration during bone colonization Z Xu, F Liu, Y Ding, T Pan, YH Wu, J Liu, IL Bado, W Zhang, L Wu, Y Gao, ... bioRxiv, 2024.05. 07.593016, 2024 | | 2024 |