| Optimal-transport analysis of single-cell gene expression identifies developmental trajectories in reprogramming G Schiebinger, J Shu, M Tabaka, B Cleary, V Subramanian, A Solomon, ... Cell 176 (4), 928-943. e22, 2019 | 738 | 2019 |
| Proteomic and phosphoproteomic comparison of human ES and iPS cells DH Phanstiel, J Brumbaugh, CD Wenger, S Tian, MD Probasco, DJ Bailey, ... Nature methods 8 (10), 821-827, 2011 | 314 | 2011 |
| The histone chaperone CAF-1 safeguards somatic cell identity S Cheloufi, U Elling, B Hopfgartner, YL Jung, J Murn, M Ninova, ... Nature 528 (7581), 218-224, 2015 | 287 | 2015 |
| Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells J Choi, AJ Huebner, K Clement, RM Walsh, A Savol, K Lin, H Gu, ... Nature 548 (7666), 219-223, 2017 | 255 | 2017 |
| Transcription factors drive Tet2-mediated enhancer demethylation to reprogram cell fate JL Sardina, S Collombet, TV Tian, A Gómez, B Di Stefano, C Berenguer, ... Cell stem cell 23 (5), 727-741. e9, 2018 | 230 | 2018 |
| Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs J Van Etten, TL Schagat, J Hrit, CA Weidmann, J Brumbaugh, JJ Coon, ... Journal of Biological Chemistry 287 (43), 36370-36383, 2012 | 219 | 2012 |
| Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cells D Phanstiel, J Brumbaugh, WT Berggren, K Conard, X Feng, ... Proceedings of the National Academy of Sciences 105 (11), 4093-4098, 2008 | 205 | 2008 |
| Nudt21 controls cell fate by connecting alternative polyadenylation to chromatin signaling J Brumbaugh, B Di Stefano, X Wang, M Borkent, E Forouzmand, ... Cell 172 (1), 106-120. e21, 2018 | 168 | 2018 |
| Small molecules facilitate rapid and synchronous iPSC generation O Bar-Nur, J Brumbaugh, C Verheul, E Apostolou, I Pruteanu-Malinici, ... Nature methods 11 (11), 1170-1176, 2014 | 132 | 2014 |
| Lineage conversion induced by pluripotency factors involves transient passage through an iPSC stage O Bar-Nur, C Verheul, AG Sommer, J Brumbaugh, BA Schwarz, I Lipchina, ... Nature biotechnology 33 (7), 761-768, 2015 | 124 | 2015 |
| Phosphorylation regulates human OCT4 J Brumbaugh, Z Hou, JD Russell, SE Howden, P Yu, AR Ledvina, ... Proceedings of the national academy of sciences 109 (19), 7162-7168, 2012 | 104 | 2012 |
| The RNA helicase DDX6 controls cellular plasticity by modulating P-body homeostasis B Di Stefano, EC Luo, C Haggerty, S Aigner, J Charlton, J Brumbaugh, ... Cell stem cell 25 (5), 622-638. e13, 2019 | 101 | 2019 |
| Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells B Di Stefano, M Ueda, S Sabri, J Brumbaugh, AJ Huebner, A Sahakyan, ... Nature methods 15 (9), 732-740, 2018 | 85 | 2018 |
| DUSP9 modulates DNA hypomethylation in female mouse pluripotent stem cells J Choi, K Clement, AJ Huebner, J Webster, CM Rose, J Brumbaugh, ... Cell stem cell 20 (5), 706-719. e7, 2017 | 79 | 2017 |
| Reconstruction of developmental landscapes by optimal-transport analysis of single-cell gene expression sheds light on cellular reprogramming G Schiebinger, J Shu, M Tabaka, B Cleary, V Subramanian, A Solomon, ... BioRxiv, 191056, 2017 | 73 | 2017 |
| A serial shRNA screen for roadblocks to reprogramming identifies the protein modifier SUMO2 M Borkent, BD Bennett, B Lackford, O Bar-Nur, J Brumbaugh, L Wang, ... Stem cell reports 6 (5), 704-716, 2016 | 64 | 2016 |
| Instant spectral assignment for advanced decision tree-driven mass spectrometry DJ Bailey, CM Rose, GC McAlister, J Brumbaugh, P Yu, CD Wenger, ... Proceedings of the National Academy of Sciences 109 (22), 8411-8416, 2012 | 62 | 2012 |
| Nuclear deformation guides chromatin reorganization in cardiac development and disease B Seelbinder, S Ghosh, SE Schneider, AK Scott, AG Berman, CJ Goergen, ... Nature biomedical engineering 5 (12), 1500-1516, 2021 | 59 | 2021 |
| A dual parameter FRET probe for measuring PKC and PKA activity in living cells J Brumbaugh, A Schleifenbaum, A Gasch, M Sattler, C Schultz Journal of the American Chemical Society 128 (1), 24-25, 2006 | 57 | 2006 |
| NANOG is multiply phosphorylated and directly modified by ERK2 and CDK1 in vitro J Brumbaugh, JD Russell, P Yu, MS Westphall, JJ Coon, JA Thomson Stem cell reports 2 (1), 18-25, 2014 | 56 | 2014 |
