Paclitaxel. FY Alqahtani, FS Aleanizy, E El Tahir, HM Alkahtani, BT AlQuadeib Profiles of drug substances, excipients, and related methodology 44, 205-238, 2019 | 125 | 2019 |
Sorafenib. AA Abdelgalil, HM Alkahtani, FI Al-Jenoobi Profiles of drug substances, excipients, and related methodology 44, 239-266, 2019 | 120 | 2019 |
Synthesis and biological evaluation of benzo [d] imidazole derivatives as potential anti-cancer agents HM Alkahtani, AY Abbas, S Wang Bioorganic & medicinal chemistry letters 22 (3), 1317-1321, 2012 | 99 | 2012 |
Synthesis and evaluation of new coumarin derivatives as antioxidant, antimicrobial, and anti-inflammatory agents HM Alshibl, ES Al-Abdullah, ME Haiba, HM Alkahtani, GEA Awad, ... Molecules 25 (14), 3251, 2020 | 87 | 2020 |
Synthesis and in vitro anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents WM Eldehna, GS Hassan, ST Al-Rashood, T Al-Warhi, AE Altyar, ... Journal of enzyme inhibition and medicinal chemistry 34 (1), 322-332, 2019 | 79 | 2019 |
Erlotinib AA Abdelgalil, HM Al-Kahtani, FI Al-Jenoobi Profiles of Drug Substances, Excipients and Related Methodology 45, 93-117, 2020 | 73 | 2020 |
New bis ([1, 2, 4] triazolo)[4, 3-a: 3′, 4′-c] quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer … MM Alanazi, HA Mahdy, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... Bioorganic Chemistry 112, 104949, 2021 | 70 | 2021 |
Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer WM Eldehna, A Nocentini, ST Al-Rashood, GS Hassan, HM Alkahtani, ... Bioorganic Chemistry 81, 425-432, 2018 | 70 | 2018 |
Antitumor properties of certain spirooxindoles towards hepatocellular carcinoma endowed with antioxidant activity ST Al-Rashood, AR Hamed, GS Hassan, HM Alkahtani, AA Almehizia, ... Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 831-839, 2020 | 66 | 2020 |
SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX WM Eldehna, MF Abo-Ashour, E Berrino, D Vullo, HA Ghabbour, ... Bioorganic chemistry 83, 549-558, 2019 | 57 | 2019 |
New quinoxaline-based VEGFR-2 inhibitors: Design, synthesis, and antiproliferative evaluation with in silico docking, ADMET, toxicity, and DFT studies MM Alanazi, H Elkady, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... RSC advances 11 (48), 30315-30328, 2021 | 54 | 2021 |
Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2 HM Alkahtani, AN Abdalla, AJ Obaidullah, MM Alanazi, AA Almehizia, ... Bioorganic Chemistry 95, 103461, 2020 | 50 | 2020 |
Synthesis, anticancer and apoptosis-inducing activities of quinazoline–isatin conjugates: epidermal growth factor receptor-tyrosine kinase assay and molecular docking studies AS El-Azab, A Al-Dhfyan, AAM Abdel-Aziz, LA Abou-Zeid, HM Alkahtani, ... Journal of Enzyme Inhibition and Medicinal Chemistry 32 (1), 935-944, 2017 | 45 | 2017 |
Synthesis, anticancer, apoptosis-inducing activities and EGFR and VEGFR2 assay mechanistic studies of 5, 5-diphenylimidazolidine-2, 4-dione derivatives: Molecular docking studies HM Alkahtani, MM Alanazi, FS Aleanizy, FY Alqahtani, A Alhoshani, ... Saudi Pharmaceutical Journal 27 (5), 682-693, 2019 | 44 | 2019 |
Mechanistic interaction study of 5, 6-Dichloro-2-[2-(pyridin-2-yl) ethyl] isoindoline-1, 3-dione with bovine serum albumin by spectroscopic and molecular docking approaches MM Alanazi, AA Almehizia, AH Bakheit, NA Alsaif, HM Alkahtani, TA Wani Saudi Pharmaceutical Journal 27 (3), 341-347, 2019 | 40 | 2019 |
Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies MM Alanazi, A Elwan, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1732-1750, 2021 | 39 | 2021 |
A series of isatin-hydrazones with cytotoxic activity and CDK2 kinase inhibitory activity: a potential type II ATP competitive inhibitor HS Al-Salem, M Arifuzzaman, HM Alkahtani, AN Abdalla, IS Issa, ... Molecules 25 (19), 4400, 2020 | 37 | 2020 |
Targeting microbial resistance: Synthesis, antibacterial evaluation, DNA binding and modeling study of new chalcone-based dithiocarbamate derivatives M Ayman, SM El-Messery, EE Habib, ST Al-Rashood, AA Almehizia, ... Bioorganic Chemistry 85, 282-292, 2019 | 37 | 2019 |
Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5 (4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX … WM Eldehna, MA Abdelrahman, A Nocentini, S Bua, ST Al-Rashood, ... Bioorganic Chemistry 90, 103102, 2019 | 26 | 2019 |
Toward the identification of potential α-ketoamide covalent inhibitors for SARS-CoV-2 main protease: Fragment-based drug design and MM-PBSA calculations MAE Hassab, M Fares, MKAH Amin, ST Al-Rashood, A Alharbi, ... Processes 9 (6), 1004, 2021 | 24 | 2021 |