Dynein motors transport activated Trks to promote survival of target-dependent neurons HM Heerssen, MF Pazyra, RA Segal Nature neuroscience 7 (6), 596-604, 2004 | 265 | 2004 |
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities M Gruber Filbin, SK Dabral, MF Pazyra-Murphy, S Ramkissoon, AL Kung, ... Nature medicine 19 (11), 1518-1523, 2013 | 143 | 2013 |
The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability KE Cosker, SJ Fenstermacher, MF Pazyra-Murphy, HL Elliott, RA Segal Nature neuroscience 19 (5), 690-696, 2016 | 137 | 2016 |
Paclitaxel reduces axonal Bclw to initiate IP3R1-dependent axon degeneration SE Pease-Raissi, MF Pazyra-Murphy, Y Li, F Wachter, Y Fukuda, ... Neuron 96 (2), 373-386. e6, 2017 | 101 | 2017 |
A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w MF Pazyra-Murphy, A Hans, SL Courchesne, C Karch, KE Cosker, ... Journal of Neuroscience 29 (20), 6700-6709, 2009 | 91 | 2009 |
Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses JA Chan, S Balasubramanian, RM Witt, KJ Nazemi, Y Choi, ... Nature neuroscience 12 (4), 409-417, 2009 | 89 | 2009 |
Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration KE Cosker, MF Pazyra-Murphy, SJ Fenstermacher, RA Segal Journal of Neuroscience 33 (12), 5195-5207, 2013 | 81 | 2013 |
Heparan Sulfate Proteoglycans Containing a Glypican 5 Core and 2-O-Sulfo-iduronic Acid Function as Sonic Hedgehog Co-receptors to Promote Proliferation*♦ RM Witt, ML Hecht, MF Pazyra-Murphy, SM Cohen, C Noti, ... Journal of Biological Chemistry 288 (36), 26275-26288, 2013 | 74 | 2013 |
Sensory neuropathy attributable to loss of Bcl-w SL Courchesne, C Karch, MF Pazyra-Murphy, RA Segal Journal of Neuroscience 31 (5), 1624-1634, 2011 | 61 | 2011 |
A transposon screen identifies loss of primary cilia as a mechanism of resistance to SMO inhibitors X Zhao, E Pak, KJ Ornell, MF Pazyra-Murphy, EL MacKenzie, ... Cancer discovery 7 (12), 1436-1449, 2017 | 60 | 2017 |
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN Y Li, MF Pazyra-Murphy, D Avizonis, M de Sá Tavares Russo, S Tang, ... Journal of Cell Biology 221 (2), e202106080, 2021 | 53 | 2021 |
Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival Y Fukuda, MF Pazyra-Murphy, ES Silagi, OE Tasdemir-Yilmaz, Y Li, ... Journal of Cell Biology 220 (1), e202005051, 2020 | 52 | 2020 |
The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis A Eisner, MF Pazyra-Murphy, E Durresi, P Zhou, X Zhao, EC Chadwick, ... Developmental cell 33 (1), 22-35, 2015 | 49 | 2015 |
Diversity of developing peripheral glia revealed by single-cell RNA sequencing OE Tasdemir-Yilmaz, NR Druckenbrod, OO Olukoya, W Dong, AR Yung, ... Developmental cell 56 (17), 2516-2535. e8, 2021 | 48 | 2021 |
Prolyl isomerase Pin1 regulates axon guidance by stabilizing CRMP2A selectively in distal axons M Balastik, XZ Zhou, M Alberich-Jorda, R Weissova, J Žiak, ... Cell reports 13 (4), 812-828, 2015 | 47 | 2015 |
Neuromuscular junction defects in mice with mutation of dynein heavy chain 1 SL Courchesne, MF Pazyra-Murphy, DJ Lee, RA Segal PLoS One 6 (2), e16753, 2011 | 35 | 2011 |
A brain tumor/organotypic slice co-culture system for studying tumor microenvironment and targeted drug therapies EJ Chadwick, DP Yang, MG Filbin, E Mazzola, Y Sun, O Behar, ... JoVE (Journal of Visualized Experiments), e53304, 2015 | 34 | 2015 |
A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma E Pak, EL MacKenzie, X Zhao, MF Pazyra-Murphy, PMC Park, L Wu, ... Neuro-oncology 21 (9), 1150-1163, 2019 | 30 | 2019 |
Preparation and maintenance of dorsal root ganglia neurons in compartmented cultures MF Pazyra-Murphy, RA Segal JoVE (Journal of Visualized Experiments), e951, 2008 | 29 | 2008 |
The Eya1 phosphatase mediates Shh-driven symmetric cell division of cerebellar granule cell precursors DJ Merk, P Zhou, SM Cohen, MF Pazyra-Murphy, GH Hwang, KJ Rehm, ... Developmental neuroscience 42 (5-6), 170-186, 2021 | 14 | 2021 |