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Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population K Suzuki, M Akiyama, K Ishigaki, M Kanai, J Hosoe, N Shojima, A Hozawa, ... Nature genetics 51 (3), 379-386, 2019 | 223 | 2019 |
Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes M Imamura, A Takahashi, T Yamauchi, K Hara, K Yasuda, N Grarup, ... Nature communications 7 (1), 10531, 2016 | 200 | 2016 |
NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program Y Hiraike, H Waki, J Yu, M Nakamura, K Miyake, G Nagano, R Nakaki, ... Nature Cell Biology 19 (9), 1081-1092, 2017 | 101 | 2017 |
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Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction S Sakaue, J Hirata, M Kanai, K Suzuki, M Akiyama, C Lai Too, T Arayssi, ... Nature communications 11 (1), 1569, 2020 | 76 | 2020 |
A deep learning method for HLA imputation and trans-ethnic MHC fine-mapping of type 1 diabetes T Naito, K Suzuki, J Hirata, Y Kamatani, K Matsuda, T Toda, Y Okada Nature communications 12 (1), 1639, 2021 | 66 | 2021 |
DOCK2 is involved in the host genetics and biology of severe COVID-19 H Namkoong, R Edahiro, T Takano, H Nishihara, Y Shirai, K Sonehara, ... Nature 609 (7928), 754-760, 2022 | 64 | 2022 |
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology K Suzuki, K Hatzikotoulas, L Southam, HJ Taylor, X Yin, KM Lorenz, ... Nature 627 (8003), 347-357, 2024 | 58 | 2024 |
Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer Y Lin, M Nakatochi, Y Hosono, H Ito, Y Kamatani, A Inoko, H Sakamoto, ... Nature communications 11 (1), 3175, 2020 | 53 | 2020 |
Integration of genetics and miRNA–target gene network identified disease biology implicated in tissue specificity S Sakaue, J Hirata, Y Maeda, E Kawakami, T Nii, T Kishikawa, K Ishigaki, ... Nucleic acids research 46 (22), 11898-11909, 2018 | 45 | 2018 |
A trans-ethnic Mendelian randomization study identifies causality of obesity on risk of psoriasis K Ogawa, PE Stuart, LC Tsoi, K Suzuki, RP Nair, H Mochizuki, JT Elder, ... The Journal of investigative dermatology 139 (6), 1397, 2019 | 40 | 2019 |
Structural basis and genotype–phenotype correlations of INSR mutations causing severe insulin resistance J Hosoe, H Kadowaki, F Miya, K Aizu, T Kawamura, I Miyata, K Satomura, ... Diabetes 66 (10), 2713-2723, 2017 | 40 | 2017 |
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A metagenome-wide association study of gut microbiome in patients with multiple sclerosis revealed novel disease pathology T Kishikawa, K Ogawa, D Motooka, A Hosokawa, M Kinoshita, K Suzuki, ... Frontiers in cellular and infection microbiology 10, 585973, 2020 | 36 | 2020 |
Next-generation sequencing identifies contribution of both class I and II HLA genes on susceptibility of multiple sclerosis in Japanese K Ogawa, T Okuno, K Hosomichi, A Hosokawa, J Hirata, K Suzuki, ... Journal of neuroinflammation 16, 1-9, 2019 | 31 | 2019 |