RETRACTED ARTICLE: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase TR Cox, RMH Rumney, EM Schoof, L Perryman, AM Høye, A Agrawal, ... Nature 522 (7554), 106-110, 2015 | 565 | 2015 |
Paediatric and adult malignant glioma: close relatives or distant cousins? C Jones, L Perryman, D Hargrave Nature reviews Clinical oncology 9 (7), 400-413, 2012 | 221 | 2012 |
MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase–mediated HOX/stem cell gene signature N Gaspar, L Marshall, L Perryman, DA Bax, SE Little, M Viana-Pereira, ... Cancer research 70 (22), 9243-9252, 2010 | 205 | 2010 |
Kinome-wide decoding of network-attacking mutations rewiring cancer signaling P Creixell, EM Schoof, CD Simpson, J Longden, CJ Miller, HJ Lou, ... Cell 163 (1), 202-217, 2015 | 180 | 2015 |
Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development DA Bax, SE Little, N Gaspar, L Perryman, L Marshall, M Viana-Pereira, ... PloS one 4 (4), e5209, 2009 | 135 | 2009 |
EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines DA Bax, N Gaspar, SE Little, L Marshall, L Perryman, M Regairaz, ... Clinical cancer research 15 (18), 5753-5761, 2009 | 102 | 2009 |
The lysyl oxidase like 2/3 enzymatic inhibitor, PXS‐5153A, reduces crosslinks and ameliorates fibrosis H Schilter, AD Findlay, L Perryman, TT Yow, J Moses, A Zahoor, CI Turner, ... Journal of cellular and molecular medicine 23 (3), 1759-1770, 2019 | 99 | 2019 |
Enhanced efficacy of IGF1R inhibition in pediatric glioblastoma by combinatorial targeting of PDGFRα/β A Bielen, L Perryman, GM Box, M Valenti, A de Haven Brandon, V Martins, ... Molecular cancer therapeutics 10 (8), 1407-1418, 2011 | 74 | 2011 |
Lysyl oxidase in cancer research L Perryman, JT Erler Future oncology 10 (9), 1709-1717, 2014 | 70 | 2014 |
Etoposide improves survival in high-grade glioma: a meta-analysis A Leonard, JE Wolff Anticancer research 33 (8), 3307-3315, 2013 | 44 | 2013 |
Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition A Bielen, G Box, L Perryman, L Bjerke, S Popov, Y Jamin, A Jury, ... Proceedings of the National Academy of Sciences 109 (20), E1267-E1276, 2012 | 32 | 2012 |
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer JL Chitty, M Yam, L Perryman, AL Parker, JN Skhinas, YFI Setargew, ... Nature Cancer 4 (9), 1326-1344, 2023 | 20 | 2023 |
An activity‐based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti‐fibrotic therapeutic strategies A Findlay, C Turner, H Schilter, M Deodhar, W Zhou, L Perryman, J Foot, ... Clinical and Translational Medicine 11 (11), 2021 | 17 | 2021 |
Evaluation of the response of intracranial xenografts to VEGF signaling inhibition using multiparametric MRI JKR Boult, G Box, M Vinci, L Perryman, SA Eccles, C Jones, SP Robinson Neoplasia 19 (9), 684-694, 2017 | 17 | 2017 |
Investigating intracranial tumour growth patterns with multiparametric MRI incorporating Gd‐DTPA and USPIO‐enhanced imaging JKR Boult, M Borri, A Jury, S Popov, G Box, L Perryman, SA Eccles, ... NMR in Biomedicine 29 (11), 1608-1617, 2016 | 15 | 2016 |
Over-expression of p53 mutants in LNCaP cells alters tumor growth and angiogenesis in vivo LA Perryman, JM Blair, EA Kingsley, B Szymanska, KT Ow, VW Wen, ... Biochemical and biophysical research communications 345 (3), 1207-1214, 2006 | 14 | 2006 |
Comparison of 18F-FET and 18F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma MK Nedergaard, SR Michaelsen, L Perryman, J Erler, HS Poulsen, ... Nuclear Medicine and Biology 43 (3), 198-205, 2016 | 13 | 2016 |
PROTACs targeting MLKL protect cells from necroptosis OH Rathje, L Perryman, RJ Payne, DW Hamprecht Journal of Medicinal Chemistry 66 (16), 11216-11236, 2023 | 11 | 2023 |
Brain cancer spreads L Perryman, JT Erler Science Translational Medicine 6 (247), 247fs28-247fs28, 2014 | 10 | 2014 |
Fibrosis in Mesothelioma: Potential Role of Lysyl Oxidases L Perryman, SG Gray Cancers 14 (4), 981, 2022 | 8 | 2022 |