DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2 P Cejka, E Cannavo, P Polaczek, T Masuda-Sasa, S Pokharel, ... Nature 467 (7311), 112-116, 2010 | 516 | 2010 |
Sae2 promotes dsDNA endonuclease activity within Mre11–Rad50–Xrs2 to resect DNA breaks E Cannavo, P Cejka Nature 514 (7520), 122-125, 2014 | 489 | 2014 |
Phosphorylated CtIP functions as a co-factor of the MRE11-RAD50-NBS1 endonuclease in DNA end resection R Anand, L Ranjha, E Cannavo, P Cejka Molecular cell 64 (5), 940-950, 2016 | 332 | 2016 |
Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents K Kratz, B Schöpf, S Kaden, A Sendoel, R Eberhard, C Lademann, ... Cell 142 (1), 77-88, 2010 | 329 | 2010 |
Methylation-induced G2/M arrest requires a full complement of the mismatch repair protein hMLH1 P Cejka, L Stojic, N Mojas, AM Russell, K Heinimann, E Cannavó, ... The EMBO journal 22 (9), 2245-2254, 2003 | 245 | 2003 |
Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair E Cannavo, G Marra, J Sabates-Bellver, M Menigatti, SM Lipkin, F Fischer, ... Cancer research 65 (23), 10759-10766, 2005 | 185 | 2005 |
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2 E Cannavo, B Gerrits, G Marra, R Schlapbach, J Jiricny Journal of Biological Chemistry 282 (5), 2976-2986, 2007 | 172 | 2007 |
Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection E Cannavo, P Cejka, SC Kowalczykowski Proceedings of the National Academy of Sciences 110 (18), E1661-E1668, 2013 | 155 | 2013 |
Physiological protein blocks direct the Mre11–Rad50–Xrs2 and Sae2 nuclease complex to initiate DNA end resection G Reginato, E Cannavo, P Cejka Genes & development 31 (23-24), 2325-2330, 2017 | 132 | 2017 |
Regulation of the MLH1–MLH3 endonuclease in meiosis E Cannavo, A Sanchez, R Anand, L Ranjha, J Hugener, C Adam, ... Nature 586 (7830), 618-622, 2020 | 102 | 2020 |
Xrs2 dependent and independent functions of the Mre11-Rad50 complex J Oh, A Al-Zain, E Cannavo, P Cejka, LS Symington Molecular cell 64 (2), 405-415, 2016 | 82 | 2016 |
Regulatory control of DNA end resection by Sae2 phosphorylation E Cannavo, D Johnson, SN Andres, VM Kissling, JK Reinert, V Garcia, ... Nature communications 9 (1), 4016, 2018 | 80 | 2018 |
Stepwise 5′ DNA end-specific resection of DNA breaks by the Mre11-Rad50-Xrs2 and Sae2 nuclease ensemble E Cannavo, G Reginato, P Cejka Proceedings of the National Academy of Sciences 116 (12), 5505-5513, 2019 | 66 | 2019 |
In vitro antitumour activity of resveratrol in human melanoma cells sensitive or resistant to temozolomide MP Fuggetta, S D'Atri, G Lanzilli, M Tricarico, E Cannavò, G Zambruno, ... Melanoma Research 14 (3), 189-196, 2004 | 65 | 2004 |
High expression of the mismatch repair protein MSH6 is associated with poor patient survival in melanoma E Alvino, F Passarelli, E Cannavò, C Fortes, S Mastroeni, S Caporali, ... American journal of clinical pathology 142 (1), 121-132, 2014 | 29 | 2014 |
Inhibition of MRN activity by a telomere protein motif F Khayat, E Cannavo, M Alshmery, WR Foster, C Chahwan, M Maddalena, ... Nature Communications 12 (1), 3856, 2021 | 23 | 2021 |
Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART JD Deere, RC Kauffman, E Cannavo, J Higgins, A Villalobos, L Adamson, ... PloS one 9 (2), e87914, 2014 | 21 | 2014 |
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners A Marsella, E Gobbini, C Cassani, R Tisi, E Cannavo, G Reginato, ... Cell reports 34 (13), 2021 | 19 | 2021 |
Viral decay kinetics in the highly active antiretroviral therapy-treated rhesus macaque model of AIDS JD Deere, J Higgins, E Cannavo, A Villalobos, L Adamson, E Fromentin, ... PLoS One 5 (7), e11640, 2010 | 18 | 2010 |
Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes G Marra, S D’Atri, H Yan, C Perrera, E Cannavo’, B Vogelstein, J Jiricny Cancer Research 61 (21), 7719-7721, 2001 | 17 | 2001 |