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Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance J Zhang, X Bu, H Wang, Y Zhu, Y Geng, NT Nihira, Y Tan, Y Ci, F Wu, ... Nature 553 (7686), 91-95, 2018 | 791 | 2018 |
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Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin Z Han, W Wei, S Dunaway, JW Darnowski, P Calabresi, J Sedivy, ... Journal of Biological Chemistry 277 (19), 17154-17160, 2002 | 314 | 2002 |
Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function A Papa, L Wan, M Bonora, L Salmena, MS Song, RM Hobbs, A Lunardi, ... Cell 157 (3), 595-610, 2014 | 308 | 2014 |
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Role of p14ARF in Replicative and Induced Senescence of Human Fibroblasts W Wei, RM Hemmer, JM Sedivy Molecular and cellular biology 21 (20), 6748-6757, 2001 | 289 | 2001 |
Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4 X Dai, W Gan, X Li, S Wang, W Zhang, L Huang, S Liu, Q Zhong, J Guo, ... Nature medicine 23 (9), 1063-1071, 2017 | 284 | 2017 |
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mTOR drives its own activation via SCFβTrCP-dependent degradation of the mTOR inhibitor DEPTOR D Gao, H Inuzuka, MKM Tan, H Fukushima, JW Locasale, P Liu, L Wan, ... Molecular cell 44 (2), 290-303, 2011 | 272 | 2011 |