| A combined approach reveals a regulatory mechanism coupling Src’s kinase activity, localization, and phosphotransferase-independent functions E Ahler, AC Register, S Chakraborty, L Fang, EM Dieter, KA Sitko, ... Molecular cell 74 (2), 393-408. e20, 2019 | 64 | 2019 |
| Targeting dynamic ATP-binding site features allows discrimination between highly homologous protein kinases S Chakraborty, T Inukai, L Fang, M Golkowski, DJ Maly ACS chemical biology 14 (6), 1249-1259, 2019 | 25 | 2019 |
| Reversible 2′-OH acylation enhances RNA stability L Fang, L Xiao, YW Jun, Y Onishi, ET Kool Nature Chemistry 15 (9), 1296-1305, 2023 | 23 | 2023 |
| How ATP-competitive inhibitors allosterically modulate tyrosine kinases that contain a Src-like regulatory architecture L Fang, J Vilas-Boas, S Chakraborty, ZE Potter, AC Register, MA Seeliger, ... ACS chemical biology 15 (7), 2005-2016, 2020 | 20 | 2020 |
| Catalytic asymmetric synthesis of the Colorado potato beetle pheromone and its enantiomer SN Li, LL Fang, JC Zhong, JJ Shen, H Xu, YQ Yang, SC Hou, Q Bian Tetrahedron: Asymmetry 25 (8), 591-595, 2014 | 20 | 2014 |
| Pervasive transcriptome interactions of protein-targeted drugs L Fang, WA Velema, Y Lee, L Xiao, MG Mohsen, AM Kietrys, ET Kool Nature Chemistry 15 (10), 1374-1383, 2023 | 19 | 2023 |
| Chemoproteomic Method for Profiling Inhibitor-Bound Kinase Complexes L Fang, S Chakraborty, EM Dieter, ZE Potter, CK Lombard, DJ Maly Journal of the American Chemical Society 141 (30), 11912-11922, 2019 | 18 | 2019 |
| Diverse reagent scaffolds provide differential selectivity of 2′-OH acylation in RNA L Xiao, L Fang, S Chatterjee, ET Kool Journal of the American Chemical Society 145 (1), 143-151, 2022 | 11 | 2022 |
| Acylation probing of “generic” RNA libraries reveals critical influence of loop constraints on reactivity L Xiao, L Fang, ET Kool Cell chemical biology 29 (8), 1341-1352. e8, 2022 | 11 | 2022 |
| Profiling of the drug resistance of thousands of Src tyrosine kinase mutants uncovers a regulatory network that couples autoinhibition to the dynamics of the catalytic domain S Chakraborty, E Ahler, JJ Simon, L Fang, ZE Potter, KA Sitko, ... BioRxiv, 2021.12. 05.471322, 2021 | 9 | 2021 |
| Parallel chemoselective profiling for mapping protein structure ZE Potter, HT Lau, S Chakraborty, L Fang, M Guttman, SE Ong, ... Cell chemical biology 27 (8), 1084-1096. e4, 2020 | 9 | 2020 |
| Profiling of drug resistance in Src kinase at scale uncovers a regulatory network coupling autoinhibition and catalytic domain dynamics S Chakraborty, E Ahler, JJ Simon, L Fang, ZE Potter, KA Sitko, ... Cell Chemical Biology 31 (2), 207-220. e11, 2024 | 5 | 2024 |
| The Right Tool for the Job: A Chemical and Genetic Toolkit for Interrogating DCLK1 L Fang, DJ Maly Cell Chemical Biology 27 (10), 1221-1223, 2020 | 2 | 2020 |
| Reversible RNA Acylation Using Bio-Orthogonal Chemistry Enables Temporal Control of CRISPR-Cas9 Nuclease Activity B Pandit, L Fang, ET Kool, M Royzen ACS Chemical Biology, 2024 | | 2024 |
| Chemically reversible 2-oh acylation protects rna from hydrolytic and enzymatic degradation L Fang, ET Kool US Patent App. 18/377,236, 2024 | | 2024 |
| Efficient post-synthesis incorporation and conjugation of reactive ketones in RNA via 2′-acylation R Shioi, L Xiao, L Fang, ET Kool Chemical Communications 60 (2), 232-235, 2024 | | 2024 |
| Reactivity-based RNA profiling for analyzing transcriptome interactions of small molecules in human cells L Fang, ET Kool STAR protocols 4 (4), 102670, 2023 | | 2023 |
| 2′-OH as a universal handle for studying intracellular RNAs L Xiao, L Fang, ET Kool Cell Chemical Biology, 2023 | | 2023 |
| RNA Infrastructure Profiling Illuminates Transcriptome Structure in Crowded Spaces L Xiao, L Fang, ET Kool bioRxiv, 2023 | | 2023 |
Sujata ChakrabortySenior Scientist I在 revmed.com 的电子邮件经过验证
