| Microglial inflammatory signaling orchestrates the hypothalamic immune response to dietary excess and mediates obesity susceptibility M Valdearcos, JD Douglass, MM Robblee, MD Dorfman, DR Stifler, ... Cell metabolism 26 (1), 185-197. e3, 2017 | 451 | 2017 |
| Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation JD Douglass, MD Dorfman, R Fasnacht, LD Shaffer, JP Thaler Molecular metabolism 6 (4), 366-373, 2017 | 242 | 2017 |
| Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice MD Dorfman, JE Krull, JD Douglass, R Fasnacht, F Lara-Lince, TH Meek, ... Nature communications 8 (1), 14556, 2017 | 166 | 2017 |
| Correlations between synaptic initiation and meiotic recombination: a study of humans and mice JR Gruhn, N Al-Asmar, R Fasnacht, H Maylor-Hagen, V Peinado, C Rubio, ... The American Journal of Human Genetics 98 (1), 102-115, 2016 | 32 | 2016 |
| ALDH enzyme expression is independent of the spermatogenic cycle, and their inhibition causes misregulation of murine spermatogenic processes T Kent, SL Arnold, R Fasnacht, R Rowsey, D Mitchell, CA Hogarth, ... Biology of Reproduction 94 (1), 12, 1-13, 2016 | 31 | 2016 |
| Prostaglandin PGE2 receptor EP4 regulates microglial phagocytosis and increases susceptibility to diet-induced obesity A Niraula, RD Fasnacht, KM Ness, JM Frey, SA Cuschieri, MD Dorfman, ... Diabetes 72 (2), 233-244, 2023 | 18 | 2023 |
| CX3CL1 action on microglia protects from diet-induced obesity by restoring POMC neuronal excitability and melanocortin system activity impaired by high-fat diet feeding J Banerjee, MD Dorfman, R Fasnacht, JD Douglass, AC Wyse-Jackson, ... International Journal of Molecular Sciences 23 (12), 6380, 2022 | 17 | 2022 |
| Obesity-associated microglial inflammatory activation paradoxically improves glucose tolerance JD Douglass, KM Ness, M Valdearcos, A Wyse-Jackson, MD Dorfman, ... Cell Metabolism 35 (9), 1613-1629. e8, 2023 | 14 | 2023 |
| Astrocyte IKKbeta/NF-kappaB signaling is required for diet-induced obesity and hypothalamic inflammation. Mol Metab 6: 366–373 JD Douglass, MD Dorfman, R Fasnacht, LD Shaffer, JP Thaler | 13 | 2017 |
| Central androgen action reverses hypothalamic astrogliosis and atherogenic risk factors induced by orchiectomy and high-fat diet feeding in male mice MD Dorfman, T Monfeuga, SJ Melhorn, JE Kanter, JM Frey, RD Fasnacht, ... American Journal of Physiology-Endocrinology and Metabolism 324 (5), E461-E475, 2023 | 3 | 2023 |
| A novel bispecific CD8 Treg modulator targeting cytolytic CD8 regulatory T cells reduces pathogenic CD4 T cells and inflammation in translational models of intestinal … J Gardell, D Boster, J Bowser, C Crane, R Fasnacht, K Fitzpatrick, ... Inflammatory Bowel Diseases 29 (Supplement_1), S12-S12, 2023 | 1 | 2023 |
| Microglial inflammatory activation paradoxically improves glucose tolerance during diet-induced obesity JD Douglass, M Valdearcos, KM Ness, A Wyse-Jackson, MD Dorfman, ... Biorxiv, 2022.04. 19.488819, 2022 | 1 | 2022 |
| Su1736 MTX-101, A BISPECIFIC CD8 TREG MODULATOR, CORRECTS THE DYSFUNCTION IN CROHN'S PATIENT CD8 TREG TO RESTORE IMMUNE BALANCE JL Gardell, L Bogatzki, D Boster, J Bowser, M Childs, R Fasnacht, ... Gastroenterology 166 (5), S-791, 2024 | | 2024 |
| Pre-Clinical Characterization of MTX-101, a Novel Bispecific CD8 Treg Modulator with the Potential to Restore CD8 Treg Functions in Patients with Rheumatological Autoimmune … D Patton, M Maurer, N Morgan, M Pham, D Boster, J Huard, C Tan, ... ARTHRITIS & RHEUMATOLOGY 75, 143-144, 2023 | | 2023 |
| Neural Controls of Metabolism: Central androgen action reverses hypothalamic astrogliosis and atherogenic risk factors induced by orchiectomy and high-fat diet feeding in male mice MD Dorfman, T Monfeuga, SJ Melhorn, JE Kanter, JM Frey, RD Fasnacht, ... American Journal of Physiology-Endocrinology and Metabolism 324 (5), E461, 2023 | | 2023 |
| Su1210 A NOVEL BISPECIFIC CD8 TREG MODULATOR TARGETING CYTOLYTIC CD8 REGULATORY T CELLS REDUCES PATHOGENIC CD4 T CELLS AND INFLAMMATION IN TRANSLATIONAL MODELS OF INTESTINAL … JL Gardell, D Boster, J Bowser, C Crane, R Fasnacht, K Fitzpatrick, ... Gastroenterology 164 (6), S-551, 2023 | | 2023 |
| A KIR x CD8 targeting bispecific modulator enhances regulatory CD8 T cell functions, and reduces inflammation in models of autoimmune disease JL Gardell, D Boster, J Bowser, R Fasnacht, K Fitzpatrick, G Hermansky, ... The Journal of Immunology 210 (1_Supplement), 85.17-85.17, 2023 | | 2023 |
| Demonstration of regulatory CD8 T cell prevalence, phenotype, and functions in autoimmune patients treated with a tolerizing peptide vaccine M Maurer, J Bowser, R Fasnacht, JL Gardell, S Julien, M Templeton, ... The Journal of Immunology 208 (1_Supplement), 123.10-123.10, 2022 | | 2022 |
| Bispecific CD8 Treg modulators regulate a novel regulatory CD8 T cell network and eliminate pathogenic CD4 T cells in live cell co-culture system JL Gardell, C Crane, J Bowser, R Fasnacht, S Julien, ME Maurer, ... The Journal of Immunology 208 (1_Supplement), 174.16-174.16, 2022 | | 2022 |
| A NEWLY DISCOVERED REGULATORY CD8 T CELL NETWORK HAS THE POTENTIAL TO REGULATE AND ELIMINATE PATHOGENIC CD4 T CELLS IN AUTOIMMUNE MEDIATED DISEASE OF THE GUT C Crane, J Bowser, R Fasnacht, J Gardell, M Maurer, S Julien, ... Inflammatory Bowel Diseases 28 (Supplement_1), S55-S55, 2022 | | 2022 |
