| Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes MT Reetz, JD Carballeira Nature protocols 2 (4), 891-903, 2007 | 988 | 2007 |
| Expanding the range of substrate acceptance of enzymes: combinatorial active‐site saturation test MT Reetz, M Bocola, JD Carballeira, D Zha, A Vogel Angewandte Chemie International Edition 44 (27), 4192-4196, 2005 | 638 | 2005 |
| Iterative saturation mutagenesis on the basis of B factors as a strategy for increasing protein thermostability MT Reetz, JD Carballeira, A Vogel Angewandte Chemie 118 (46), 7909-7915, 2006 | 631 | 2006 |
| Iterative saturation mutagenesis accelerates laboratory evolution of enzyme stereoselectivity: rigorous comparison with traditional methods MT Reetz, S Prasad, JD Carballeira, Y Gumulya, M Bocola Journal of the American Chemical Society 132 (26), 9144-9152, 2010 | 259 | 2010 |
| Isolation and biochemical characterization of two novel metagenome-derived esterases C Elend, C Schmeisser, C Leggewie, P Babiak, JD Carballeira, HL Steele, ... Applied and environmental microbiology 72 (5), 3637-3645, 2006 | 234 | 2006 |
| Microbial cells as catalysts for stereoselective red–ox reactions JD Carballeira, MA Quezada, P Hoyos, Y Simeó, MJ Hernaiz, ... Biotechnology advances 27 (6), 686-714, 2009 | 211 | 2009 |
| Increasing the stability of an enzyme toward hostile organic solvents by directed evolution based on iterative saturation mutagenesis using the B-FIT method MT Reetz, P Soni, L Fernández, Y Gumulya, JD Carballeira Chemical communications 46 (45), 8657-8658, 2010 | 195 | 2010 |
| Expanding the substrate scope of enzymes: combining mutations obtained by CASTing MT Reetz, JD Carballeira, J Peyralans, H Höbenreich, A Maichele, ... Chemistry–A European Journal 12 (23), 6031-6038, 2006 | 194 | 2006 |
| Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates J Sanchis, L Fernández, JD Carballeira, J Drone, Y Gumulya, ... Applied microbiology and biotechnology 81, 387-397, 2008 | 155 | 2008 |
| Learning from directed evolution: further lessons from theoretical investigations into cooperative mutations in lipase enantioselectivity MT Reetz, M Puls, JD Carballeira, A Vogel, KE Jaeger, T Eggert, W Thiel, ... ChemBioChem 8 (1), 106-112, 2007 | 127 | 2007 |
| Enzyme promiscuity: first protein-catalyzed Morita–Baylis–Hillman reaction MT Reetz, R Mondiere, JD Carballeira Tetrahedron letters 48 (10), 1679-1681, 2007 | 117 | 2007 |
| Alternate‐Site Enzyme Promiscuity A Taglieber, H Höbenreich, JD Carballeira, RJG Mondière, MT Reetz Angewandte Chemie 119 (45), 8751-8754, 2007 | 66 | 2007 |
| Gongronella butleri, Schizosaccharomyces octosporus and Diplogelasinospora grovesii: novel microorganisms useful for the stereoselective reduction of ketones JD Carballeira, M Valmaseda, E Alvarez, JVS Gago Enzyme and microbial technology 34 (6), 611-623, 2004 | 49 | 2004 |
| Leishmanicidal activity of passifloricin A and derivatives F Echeverri Molecules 9 (8), 666-672, 2004 | 48* | 2004 |
| Monascus kaoliang CBS 302.78 immobilized in polyurethane foam using iso-propanol as co-substrate: optimized immobilization conditions of a fungus as biocatalyst for the … MA Quezada, JD Carballeira, JV Sinisterra Bioresource Technology 100 (6), 2018-2025, 2009 | 44 | 2009 |
| Diplogelasinospora grovesii IMI 171018, a new whole cell biocatalyst for the stereoselective reduction of ketones JD Carballeira, E Alvarez, M Campillo, L Pardo, JV Sinisterra Tetrahedron: Asymmetry 15 (6), 951-962, 2004 | 44 | 2004 |
| Highly stereoselective reduction of haloketones using three new yeasts: application to the synthesis of (S)-adrenergic β-blockers related to propranolol FM Lagos, JD Carballeira, JL Bermudez, E Alvarez, JV Sinisterra Tetrahedron: Asymmetry 15 (5), 763-770, 2004 | 44 | 2004 |
| Biotransformation of cyclohexanone using immobilized Geotrichum candidum NCYC49: factors affecting the selectivity of the process JD Carballeira, E Álvarez, JV Sinisterra Journal of Molecular Catalysis B: Enzymatic 28 (1), 25-32, 2004 | 43 | 2004 |
| Lipase from Pseudomonas stutzeri: Purification, homology modelling and rational explanation of the substrate binding mode A Maraite, P Hoyos, JD Carballeira, ÁC Cabrera, ... Journal of Molecular Catalysis B: Enzymatic 87, 88-98, 2013 | 38 | 2013 |
| Directed evolution and axial chirality: optimization of the enantioselectivity of Pseudomonas aeruginosa lipase towards the kinetic resolution of a racemic allene JD Carballeira, P Krumlinde, M Bocola, A Vogel, MT Reetz, JE Bäckvall Chemical communications, 1913-1915, 2007 | 31 | 2007 |
ANDRES R. ALCANTARAComplutense University of Madrid. Faculty of Pharmacy. Dept. Chemistry in Pharmaceutical Sciences.在 ucm.es 的电子邮件经过验证
