Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease K Lunnon, R Smith, E Hannon, PL De Jager, G Srivastava, M Volta, ... Nature neuroscience, 2014 | 557 | 2014 |
Methylomic trajectories across human fetal brain development H Spiers, E Hannon, LC Schalkwyk, R Smith, CCY Wong, MC O’Donovan, ... Genome research 25 (3), 338-352, 2015 | 309 | 2015 |
Allelic skewing of DNA methylation is widespread across the genome LC Schalkwyk, EL Meaburn, R Smith, EL Dempster, AR Jeffries, ... The American Journal of Human Genetics 86 (2), 196-212, 2010 | 291 | 2010 |
Genetic predictors of response to antidepressants in the GENDEP project R Uher, P Huezo-Diaz, N Perroud, R Smith, M Rietschel, O Mors, ... The pharmacogenomics journal 9 (4), 225-233, 2009 | 236 | 2009 |
Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: a 13-year longitudinal study CAM Cecil, LJ Lysenko, SR Jaffee, JB Pingault, RG Smith, CL Relton, ... Molecular psychiatry, 2014 | 219 | 2014 |
Moderation of antidepressant response by the serotonin transporter gene P Huezo-Diaz, R Uher, R Smith, M Rietschel, N Henigsberg, A Marušič, ... The British Journal of Psychiatry 195 (1), 30-38, 2009 | 185 | 2009 |
Elevated DNA methylation across a 48‐kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology RG Smith, E Hannon, PL De Jager, L Chibnik, SJ Lott, D Condliffe, ... Alzheimer's & Dementia 14 (12), 1580-1588, 2018 | 150 | 2018 |
Epigenetic signatures of childhood abuse and neglect: Implications for psychiatric vulnerability CAM Cecil, RG Smith, E Walton, J Mill, EJ McCrory, E Viding Journal of psychiatric research 83, 184-194, 2016 | 138 | 2016 |
Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project N Perroud, KJ Aitchison, R Uher, R Smith, P Huezo-Diaz, A Marusic, ... Neuropsychopharmacology 34 (12), 2517-2528, 2009 | 128 | 2009 |
Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex GL Shireby, JP Davies, PT Francis, J Burrage, EM Walker, GWA Neilson, ... Brain 143 (12), 3763-3775, 2020 | 118 | 2020 |
A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex RG Smith, E Pishva, G Shireby, AR Smith, JAY Roubroeks, E Hannon, ... Nature communications 12 (1), 3517, 2021 | 115 | 2021 |
Variation in 5-hydroxymethylcytosine across human cortex and cerebellum K Lunnon, E Hannon, RG Smith, E Dempster, C Wong, J Burrage, ... Genome biology 17, 1-15, 2016 | 110 | 2016 |
Genetic differences in cytochrome P450 enzymes and antidepressant treatment response K Hodgson, K Tansey, MZ Dernovšek, J Hauser, N Henigsberg, W Maier, ... Journal of psychopharmacology 28 (2), 133-141, 2014 | 108 | 2014 |
CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP P Huezo-Diaz, N Perroud, EP Spencer, R Smith, S Sim, S Virding, R Uher, ... Journal of Psychopharmacology 26 (3), 398-407, 2012 | 106 | 2012 |
Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model RG Smith, RL Kember, J Mill, C Fernandes, LC Schalkwyk, JD Buxbaum, ... PloS one 4 (12), e8456, 2009 | 100 | 2009 |
Alzheimer’s disease-associated (hydroxy) methylomic changes in the brain and blood R Lardenoije, JAY Roubroeks, E Pishva, M Leber, H Wagner, A Iatrou, ... Clinical epigenetics 11 (1), 1-15, 2019 | 99 | 2019 |
Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project R Keers, R Uher, P Huezo-Diaz, R Smith, S Jaffee, M Rietschel, ... The pharmacogenomics journal 11 (2), 138-145, 2010 | 99 | 2010 |
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease AR Smith, RG Smith, E Pishva, E Hannon, JAY Roubroeks, J Burrage, ... Clinical epigenetics 11 (1), 1-13, 2019 | 94 | 2019 |
Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain AR Smith, RG Smith, D Condliffe, E Hannon, L Schalkwyk, J Mill, ... Neurobiology of aging 47, 35-40, 2016 | 89 | 2016 |
Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases JAY Roubroeks, RG Smith, DLA van den Hove, K Lunnon Journal of neurochemistry 143 (2), 158-170, 2017 | 82 | 2017 |