Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions DM Howard, MJ Adams, TK Clarke, JD Hafferty, J Gibson, M Shirali, ... Nature neuroscience 22 (3), 343, 2019 | 1493 | 2019 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 920 | 2019 |
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways DM Howard, MJ Adams, M Shirali, TK Clarke, RE Marioni, G Davies, ... Nature communications 9 (1), 1470, 2018 | 486 | 2018 |
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N= 112 117) TK Clarke, MJ Adams, G Davies, DM Howard, LS Hall, S Padmanabhan, ... Molecular psychiatry 22 (10), 1376-1384, 2017 | 367 | 2017 |
Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism M Luciano, SP Hagenaars, G Davies, WD Hill, TK Clarke, M Shirali, ... Nature genetics 50 (1), 6-11, 2018 | 320 | 2018 |
Genome-wide association study meta-analysis of the alcohol use disorders identification test (AUDIT) in two population-based cohorts S Sanchez-Roige, AA Palmer, P Fontanillas, SL Elson, ... American Journal of Psychiatry 176 (2), 107-118, 2019 | 272 | 2019 |
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank X Shen, DM Howard, MJ Adams, WD Hill, TK Clarke, IJ Deary, ... Nature communications 11 (1), 2301, 2020 | 199* | 2020 |
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants R Nagy, TS Boutin, J Marten, JE Huffman, SM Kerr, A Campbell, ... Genome medicine 9 (1), 1-14, 2017 | 127 | 2017 |
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors N Mullins, JE Kang, AI Campos, JRI Coleman, AC Edwards, H Galfalvy, ... Biological psychiatry 91 (3), 313-327, 2022 | 106 | 2022 |
Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden RF Hillary, AJ Stevenson, DL McCartney, A Campbell, RM Walker, ... Clinical Epigenetics 12, 115, 2020 | 100 | 2020 |
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts G Ni, J Zeng, JA Revez, Y Wang, Z Zheng, T Ge, R Restuadi, J Kiewa, ... Biological psychiatry 90 (9), 611-620, 2021 | 93 | 2021 |
A meta-analysis of genome-wide association studies of epigenetic age acceleration J Gibson, TC Russ, TK Clarke, DM Howard, RF Hillary, KL Evans, ... PLOS Genetics 15 (11), e1008104, 2019 | 85 | 2019 |
Factors associated with sharing e-mail information and mental health survey participation in large population cohorts M Adams, WD Hill, DM Howard, KAS Davis, IJ Deary, M Hotopf, ... International Journal of Epidemiology, 1-12, 2019 | 79 | 2019 |
Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel … AT Amare, A Vaez, YH Hsu, N Direk, Z Kamali, DM Howard, AM McIntosh, ... Molecular psychiatry 25, 1420–1429, 2019 | 79 | 2019 |
The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study O Giannakopoulou, K Lin, X Meng, MH Su, PH Kuo, RE Peterson, ... JAMA psychiatry 78 (11), 1258-1269, 2021 | 72 | 2021 |
Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in the UK Biobank X Shen, SR Cox, MJ Adams, DM Howard, SM Lawrie, SJ Ritchie, ... Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 3 (10), 878-886, 2018 | 67 | 2018 |
Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank LS Hall, MJ Adams, A Arnau-Soler, TK Clarke, DM Howard, Y Zeng, ... Translational psychiatry 8 (1), 9, 2018 | 66 | 2018 |
Impact of polygenic risk for schizophrenia on cortical structure in UK Biobank E Neilson, X Shen, SR Cox, TK Clarke, EM Wigmore, J Gibson, ... Biological psychiatry 86 (7), 536-544, 2019 | 59 | 2019 |
Sex-dependent shared and nonshared genetic architecture across mood and psychotic disorders GAM Blokland, J Grove, CY Chen, C Cotsapas, S Tobet, R Handa, ... Biological psychiatry 91 (1), 102-117, 2022 | 56 | 2022 |
Epigenetic prediction of major depressive disorder MC Barbu, X Shen, RM Walker, DM Howard, KL Evans, HC Whalley, ... Molecular psychiatry 26 (9), 5112-5123, 2021 | 53 | 2021 |