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Brian Wipke
Brian Wipke
Senior Director of Immunology, Moderna, Inc.
在 modernatx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis
BT Wipke, PM Allen
The Journal of Immunology 167 (3), 1601-1608, 2001
7162001
Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2
U Schulze-Topphoff, M Varrin-Doyer, K Pekarek, CM Spencer, A Shetty, ...
Proceedings of the National Academy of Sciences 113 (17), 4777-4782, 2016
3022016
Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS
B Parodi, S Rossi, S Morando, C Cordano, A Bragoni, C Motta, C Usai, ...
Acta neuropathologica 130 (2), 279-295, 2015
2012015
Staging the initiation of autoantibody-induced arthritis: a critical role for immune complexes
BT Wipke, Z Wang, W Nagengast, DE Reichert, PM Allen
The Journal of Immunology 172 (12), 7694-7702, 2004
1902004
Dynamic visualization of a joint-specific autoimmune response through positron emission tomography
BT Wipke, Z Wang, J Kim, TJ McCarthy, PM Allen
Nature immunology 3 (4), 366-372, 2002
1562002
Despite ubiquitous autoantigen expression, arthritogenic autoantibody response initiates in the local lymph node
L Mandik-Nayak, BT Wipke, FF Shih, ER Unanue, PM Allen
Proceedings of the National Academy of Sciences 99 (22), 14368-14373, 2002
862002
Massive Thymic Deletion Results in Systemic Autoimmunity through Elimination of CD4+ CD25+ T Regulatory Cells
FF Shih, L Mandik-Nayak, BT Wipke, PM Allen
The Journal of experimental medicine 199 (3), 323-335, 2004
782004
Variable binding affinities of listeriolysin O peptides for the H‐2Kd class I molecule
BT Wipke, SC Jameson, MJ Bevan, EG Pamer
European journal of immunology 23 (8), 2005-2010, 1993
461993
Connexin 43 gap junction proteins are up‐regulated in remyelinating spinal cord
WA Roscoe, E Messersmith, A Meyer‐Franke, B Wipke, SJ Karlik
Journal of neuroscience research 85 (5), 945-953, 2007
422007
Anti‐CD 25 monoclonal antibody Fc variants differentially impact regulatory T cells and immune homeostasis
DJ Huss, AF Pellerin, BP Collette, AK Kannan, L Peng, A Datta, BT Wipke, ...
Immunology 148 (3), 276-286, 2016
382016
CCR2 deficiency alters activation of microglia subsets in traumatic brain injury
K Somebang, J Rudolph, I Imhof, L Li, EC Niemi, J Shigenaga, H Tran, ...
Cell Reports 36 (12), 109727, 2021
342021
Granulocyte-macrophage colony-stimulating factor mRNA and Neuroprotective Immunity in Parkinson's disease
KE Olson, KL Namminga, Y Lu, MJ Thurston, AD Schwab, S de Picciotto, ...
Biomaterials 272, 120786, 2021
332021
Kerlero de Rosbo N, Uccelli A. Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS
B Parodi, S Rossi, S Morando, C Cordano, A Bragoni, C Motta, C Usai, ...
Acta Neuropathol 130 (2), 279-295, 2015
302015
Trypanosoma cruzi infection does not impair major histocompatibility complex class I presentation of antigen to cytotoxic T lymphocytes
FS Buckner, BT Wipke, WC Van Voorhis
European journal of immunology 27 (10), 2541-2548, 1997
291997
Selective activation and expansion of regulatory T cells using lipid encapsulated mRNA encoding a long-acting IL-2 mutein
S de Picciotto, N DeVita, CJ Hsiao, C Honan, SW Tse, M Nguyen, ...
Nature communications 13 (1), 1-14, 2022
262022
Evoked potentials as a translatable biomarker to track functional remyelination
BJ Farley, E Morozova, J Dion, B Wang, BD Harvey, D Gianni, B Wipke, ...
Molecular and Cellular Neuroscience 99, 103393, 2019
252019
Defining changes in the spatial distribution and composition of brain lipids in the Shiverer and Cuprizone mouse models of myelin disease
RJ Maganti, XL Hronowski, RW Dunstan, BT Wipke, X Zhang, L Jandreski, ...
Journal of Histochemistry & Cytochemistry 67 (3), 203-219, 2019
182019
Orally available and efficacious α4β1/α4β7 integrin inhibitors
Y Xu, JL Smith, CM Semko, KI Rossiter, JY Fukuda, MS Dappen, ...
Bioorganic & medicinal chemistry letters 23 (15), 4370-4373, 2013
172013
Different Fumaric Acid Esters Elicit Distinct Pharmacologic Responses
BT Wipke, R Hoepner, K Strassburger-Krogias, AM Thomas, D Gianni, ...
Neurology-Neuroimmunology Neuroinflammation 8 (2), 2021
112021
Dimethyl fumarate and monomethyl fumarate are distinguished by non-overlapping pharmacodynamic effects in vivo (P1. 206)
M Brennan, N Allaire, D Huss, P Cullen, A Thai, S Szak, A Thomas, ...
Neurology 82 (10 Supplement), 2014
82014
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