Molecular imaging in drug development JK Willmann, N Van Bruggen, LM Dinkelborg, SS Gambhir Nature reviews Drug discovery 7 (7), 591-607, 2008 | 1375 | 2008 |
Imaging of amyloid β in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism CC Rowe, U Ackerman, W Browne, R Mulligan, KL Pike, G O'Keefe, ... The Lancet Neurology 7 (2), 129-135, 2008 | 784 | 2008 |
Application of locked nucleic acids to improve aptamer in vivo stability and targeting function KS Schmidt, S Borkowski, J Kurreck, AW Stephens, R Bald, M Hecht, ... Nucleic acids research 32 (19), 5757-5765, 2004 | 373 | 2004 |
A high-affinity human antibody that targets tumoral blood vessels L Tarli, E Balza, F Viti, L Borsi, P Castellani, D Berndorff, L Dinkelborg, ... Blood, The Journal of the American Society of Hematology 94 (1), 192-198, 1999 | 266 | 1999 |
Synthesis, 18F-Labeling, and in Vitro and in Vivo Studies of Bombesin Peptides Modified with Silicon-Based Building Blocks A Höhne, L Mu, M Honer, PA Schubiger, SM Ametamey, K Graham, ... Bioconjugate chemistry 19 (9), 1871-1879, 2008 | 178 | 2008 |
Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer’s disease and other … H Kroth, F Oden, J Molette, H Schieferstein, F Capotosti, A Mueller, ... European journal of nuclear medicine and molecular imaging 46, 2178-2189, 2019 | 166 | 2019 |
Exploratory Clinical Trial of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate for Imaging xC− Transporter Using Positron Emission Tomography in Patients with Non … S Baek, CM Choi, SH Ahn, JW Lee, G Gong, JS Ryu, SJ Oh, ... Clinical cancer research 18 (19), 5427-5437, 2012 | 144 | 2012 |
Tau PET imaging with 18F-PI-2620 in patients with Alzheimer disease and healthy controls: a first-in-humans study A Mueller, S Bullich, O Barret, J Madonia, M Berndt, C Papin, A Perrotin, ... Journal of Nuclear Medicine 61 (6), 911-919, 2020 | 143 | 2020 |
Targeting of HER2-expressing tumors with a site-specifically 99mTc-labeled recombinant affibody molecule, ZHER2: 2395, with C-terminally engineered cysteine S Ahlgren, H Wållberg, TA Tran, C Widström, M Hjertman, L Abrahmsén, ... Journal of Nuclear Medicine 50 (5), 781-789, 2009 | 142 | 2009 |
Silicon‐Based Building Blocks for One‐Step 18F‐Radiolabeling of Peptides for PET Imaging L Mu, A Höhne, PA Schubiger, SM Ametamey, K Graham, JE Cyr, ... Angewandte Chemie International Edition 47 (26), 4922-4925, 2008 | 142 | 2008 |
Specific PET Imaging of xC− Transporter Activity Using a 18F-Labeled Glutamate Derivative Reveals a Dominant Pathway in Tumor Metabolism N Koglin, A Mueller, M Berndt, H Schmitt-Willich, L Toschi, AW Stephens, ... Clinical Cancer Research 17 (18), 6000-6011, 2011 | 133 | 2011 |
Radioimmunotherapy of head and neck cancer xenografts using 131I-labeled antibody L19-SIP for selective targeting of tumor vasculature BM Tijink, D Neri, CR Leemans, M Budde, LM Dinkelborg, ... Journal of Nuclear Medicine 47 (7), 1127-1135, 2006 | 128 | 2006 |
Radioimmunotherapy of solid tumors by targeting extra domain B fibronectin: identification of the best-suited radioimmunoconjugate D Berndorff, S Borkowski, S Sieger, A Rother, M Friebe, F Viti, CS Hilger, ... Clinical cancer research 11 (19), 7053s-7063s, 2005 | 127 | 2005 |
Direct One-Step18F-Labeling of Peptides via Nucleophilic Aromatic Substitution J Becaud, L Mu, M Karramkam, PA Schubiger, SM Ametamey, K Graham, ... Bioconjugate chemistry 20 (12), 2254-2261, 2009 | 126 | 2009 |
124I-L19-SIP for immuno-PET imaging of tumour vasculature and guidance of 131I-L19-SIP radioimmunotherapy BM Tijink, LR Perk, M Budde, M Stigter-van Walsum, GWM Visser, ... European journal of nuclear medicine and molecular imaging 36, 1235-1244, 2009 | 119 | 2009 |
18F-Florbetaben PET beta-amyloid binding expressed in Centiloids CC Rowe, V Doré, G Jones, D Baxendale, RS Mulligan, S Bullich, ... European journal of nuclear medicine and molecular imaging 44, 2053-2059, 2017 | 104 | 2017 |
Imaging of tumor angiogenesis using 99mTc-labeled human recombinant anti-ED-B fibronectin antibody fragments D Berndorff, S Borkowski, D Moosmayer, F Viti, B Müller-Tiemann, ... Journal of nuclear medicine 47 (10), 1707-1716, 2006 | 100 | 2006 |
Radiation dosimetry of β-amyloid tracers 11C-PiB and 18F-BAY94-9172 GJ O'Keefe, TH Saunder, S Ng, U Ackerman, HJ Tochon-Danguy, ... Journal of Nuclear Medicine 50 (2), 309-315, 2009 | 99 | 2009 |
Aβ imaging with 18F-florbetaben in prodromal Alzheimer's disease: a prospective outcome study KT Ong, VL Villemagne, A Bahar-Fuchs, F Lamb, N Langdon, AM Catafau, ... Journal of Neurology, Neurosurgery & Psychiatry 86 (4), 431-436, 2015 | 96 | 2015 |
18F‐Radiolabeling of Aromatic Compounds Using Triarylsulfonium Salts L Mu, CR Fischer, JP Holland, J Becaud, PA Schubiger, R Schibli, ... European Journal of Organic Chemistry 2012 (5), 889-892, 2012 | 94 | 2012 |