| The evolutionary history of lethal metastatic prostate cancer G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, JMC Tubio, ... Nature 520 (7547), 353-357, 2015 | 1456 | 2015 |
| Hedgehog signalling in prostate regeneration, neoplasia and metastasis SS Karhadkar, G Steven Bova, N Abdallah, S Dhara, D Gardner, A Maitra, ... Nature 431 (7009), 707-712, 2004 | 1379 | 2004 |
| Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer R Hu, TA Dunn, S Wei, S Isharwal, RW Veltri, E Humphreys, M Han, ... Cancer research 69 (1), 16-22, 2009 | 1306 | 2009 |
| Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis. WH Lee, RA Morton, JI Epstein, JD Brooks, PA Campbell, GS Bova, ... Proceedings of the National Academy of Sciences 91 (24), 11733-11737, 1994 | 1091 | 1994 |
| Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search JR Smith, D Freije, JD Carpten, H Grönberg, J Xu, SD Isaacs, ... Science 274 (5291), 1371-1374, 1996 | 1052 | 1996 |
| Frequent Inactivation of PTEN/MMAC1 in Primary Prostate Cancer P Cairns, K Okami, S Halachmi, N Halachmi, M Esteller, JG Herman, ... Cancer research 57 (22), 4997-5000, 1997 | 1032 | 1997 |
| DPC4 Gene in Various Tumor Types M Schutte, RH Hruban, L Hedrick, KR Cho, GM Nadasdy, CL Weinstein, ... Cancer research 56 (11), 2527-2530, 1996 | 991 | 1996 |
| Hereditary prostate cancer: epidemiologic and clinical features BS Carter, GS Bova, TH Beaty, GD Steinberg, B Childs, WB Isaacs, ... The Journal of urology 150 (3), 797-802, 1993 | 949 | 1993 |
| Frequency of homozygous deletion at p16/CDKN2 in primary human tumours P Cairns, TJ Polascik, Y Eby, K Tokino, J Califano, A Merlo, L Mao, ... Nature genetics 11 (2), 210-212, 1995 | 827 | 1995 |
| Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer W Liu, S Laitinen, S Khan, M Vihinen, J Kowalski, G Yu, L Chen, ... Nature medicine 15 (5), 559-565, 2009 | 748 | 2009 |
| Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements MC Haffner, MJ Aryee, A Toubaji, DM Esopi, R Albadine, B Gurel, ... Nature genetics 42 (8), 668-675, 2010 | 676 | 2010 |
| Evidence for a prostate cancer susceptibility locus on the X chromosome. J Xu, D Meyers, D Freije, S Isaacs, K Wiley, D Nusskern, C Ewing, ... Nature genetics 20 (2), 175-179, 1998 | 644 | 1998 |
| Interfocal Heterogeneity of PTEN/MMAC1 Gene Alterations in Multiple Metastatic Prostate Cancer Tissues H Suzuki, D Freije, DR Nusskern, K Okami, P Cairns, D Sidransky, ... Cancer research 58 (2), 204-209, 1998 | 628 | 1998 |
| Hypermethylation of CpG islands in primary and metastatic human prostate cancer S Yegnasubramanian, J Kowalski, ML Gonzalgo, M Zahurak, ... Cancer research 64 (6), 1975-1986, 2004 | 611 | 2004 |
| Telomerase activity: a prevalent marker of malignant human prostate tissue HJ Sommerfeld, AK Meeker, MA Piatyszek, GS Bova, JW Shay, DS Coffey Cancer research 56 (1), 218-222, 1996 | 565 | 1996 |
| Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers GH Su, RH Hruban, RK Bansal, GS Bova, DJ Tang, MC Shekher, ... The American journal of pathology 154 (6), 1835-1840, 1999 | 524 | 1999 |
| Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping ML Cher, GS Bova, DH Moore, EJ Small, PR Carroll, SS Pin, JI Epstein, ... Cancer research 56 (13), 3091-3102, 1996 | 501 | 1996 |
| Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer GS Bova, BS Carter, MJG Bussemakers, M Emi, Y Fujiwara, N Kyprianou, ... Cancer research 53 (17), 3869-3873, 1993 | 498 | 1993 |
| Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer JB Nelson, K Chan-Tack, SP Hedican, SR Magnuson, TJ Opgenorth, ... Cancer research 56 (4), 663-668, 1996 | 454 | 1996 |
| Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk J Xu, SL Zheng, A Komiya, JC Mychaleckyj, SD Isaacs, JJ Hu, D Sterling, ... Nature genetics 32 (2), 321-325, 2002 | 450 | 2002 |
William B. IsaacsProfessor of Urology and Oncology, Brady Urological Inst, Johns Hopkins Univ, School of Medicine在 jhmi.edu 的电子邮件经过验证
