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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity FA Ran, PD Hsu, CY Lin, JS Gootenberg, S Konermann, AE Trevino, ... Cell 154 (6), 1380-1389, 2013 | 4223 | 2013 |
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Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases W Xu, H Yang, Y Liu, Y Yang, P Wang, SH Kim, S Ito, C Yang, P Wang, ... Cancer cell 19 (1), 17-30, 2011 | 3069 | 2011 |
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The diverse functions of histone lysine methylation C Martin, Y Zhang Nature Reviews Molecular Cell Biology 6 (11), 838-849, 2005 | 2610 | 2005 |
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TET enzymes, TDG and the dynamics of DNA demethylation RM Kohli, Y Zhang Nature 502 (7472), 472-479, 2013 | 1826 | 2013 |
Role of histone H3 lysine 27 methylation in X inactivation K Plath, J Fang, SK Mlynarczyk-Evans, R Cao, KA Worringer, H Wang, ... Science 300 (5616), 131-135, 2003 | 1512 | 2003 |
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TET-mediated active DNA demethylation: mechanism, function and beyond X Wu, Y Zhang Nature Reviews Genetics 18 (9), 517-534, 2017 | 1447 | 2017 |
Active DNA demethylation: many roads lead to Rome SC Wu, Y Zhang Nature Reviews Molecular Cell Biology 11 (9), 607-620, 2010 | 1326 | 2010 |
New nomenclature for chromatin-modifying enzymes CD Allis, SL Berger, J Cote, S Dent, T Jenuwien, T Kouzarides, L Pillus, ... Cell 131 (4), 633-636, 2007 | 1181 | 2007 |
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex HH Ng, Y Zhang, B Hendrich, CA Johnson, BM Turner, ... Nature genetics 23 (1), 58-61, 1999 | 1179 | 1999 |
Reversing DNA methylation: mechanisms, genomics, and biological functions H Wu, Y Zhang Cell 156 (1), 45-68, 2014 | 1175 | 2014 |
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