| A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation A Grubman, G Chew, JF Ouyang, G Sun, XY Choo, C McLean, ... Nature neuroscience 22 (12), 2087-2097, 2019 | 670 | 2019 |
| Oral treatment with CuII (atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis BR Roberts, NKH Lim, EJ McAllum, PS Donnelly, DJ Hare, PA Doble, ... Journal of Neuroscience 34 (23), 8021-8031, 2014 | 177 | 2014 |
| Transcriptional signature in microglia associated with Aβ plaque phagocytosis A Grubman, XY Choo, G Chew, JF Ouyang, G Sun, NP Croft, FJ Rossello, ... Nature communications 12 (1), 3015, 2021 | 172 | 2021 |
| Copper as a key regulator of cell signalling pathways A Grubman, AR White Expert reviews in molecular medicine 16, e11, 2014 | 170 | 2014 |
| Reprogramming roadmap reveals route to human induced trophoblast stem cells X Liu, JF Ouyang, FJ Rossello, JP Tan, KC Davidson, DS Valdes, ... Nature 586 (7827), 101-107, 2020 | 156 | 2020 |
| The innate immune molecule, NOD1, regulates direct killing of Helicobacter pylori by antimicrobial peptides A Grubman, M Kaparakis, J Viala, C Allison, L Badea, A Karrar, IG Boneca, ... Cellular microbiology 12 (5), 626-639, 2010 | 147 | 2010 |
| TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway D Moujalled, A Grubman, K Acevedo, S Yang, YD Ke, DM Moujalled, ... Human Molecular Genetics 26 (9), 1732-1746, 2017 | 78 | 2017 |
| Neuroinflammation and copper in Alzheimer’s disease XY Choo, L Alukaidey, AR White, A Grubman International Journal of Alzheimer’s Disease 2013 (1), 145345, 2013 | 73 | 2013 |
| Nucleotide oligomerization domain 1 enhances IFN-γ signaling in gastric epithelial cells during Helicobacter pylori infection and exacerbates disease severity CC Allison, J Ferrand, L McLeod, M Hassan, M Kaparakis-Liaskos, ... The Journal of Immunology 190 (7), 3706-3715, 2013 | 72 | 2013 |
| Kinase inhibitor screening identifies cyclin-dependent kinases and glycogen synthase kinase 3 as potential modulators of TDP-43 cytosolic accumulation during cell stress D Moujalled, JL James, SJ Parker, GE Lidgerwood, C Duncan, ... PloS one 8 (6), e67433, 2013 | 69 | 2013 |
| Astrocyte remodeling in the beneficial effects of long-term voluntary exercise in Alzheimer’s disease I Belaya, M Ivanova, A Sorvari, M Ilicic, S Loppi, H Koivisto, A Varricchio, ... Journal of neuroinflammation 17, 1-19, 2020 | 64 | 2020 |
| Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass … DJ Hare, A Grubman, TM Ryan, A Lothian, JR Liddell, R Grimm, ... Metallomics 5 (12), 1656-1662, 2013 | 58 | 2013 |
| Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43 D Moujalled, JL James, S Yang, K Zhang, C Duncan, DM Moujalled, ... Human molecular genetics 24 (6), 1655-1669, 2015 | 54 | 2015 |
| Vitamin B6 Is Required for Full Motility and Virulence in Helicobacter pylori A Grubman, A Phillips, M Thibonnier, M Kaparakis-Liaskos, C Johnson, ... MBio 1 (3), 10.1128/mbio. 00112-10, 2010 | 54 | 2010 |
| A high-resolution map of human RNA translation SP Chothani, E Adami, AA Widjaja, SR Langley, S Viswanathan, CJ Pua, ... Molecular cell 82 (15), 2885-2899. e8, 2022 | 51 | 2022 |
| Increased metal content in the TDP-43A315T transgenic mouse model of frontotemporal lobar degeneration and amyotrophic lateral sclerosis TNT Dang, NKH Lim, A Grubman, QX Li, I Volitakis, AR White, PJ Crouch Frontiers in aging neuroscience 6, 15, 2014 | 50 | 2014 |
| PPARβ/δ‐agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1ΔE9 astrocytes H Konttinen, I Gureviciene, M Oksanen, A Grubman, S Loppi, ... Glia 67 (1), 146-159, 2019 | 49 | 2019 |
| The Copper bis(thiosemicarbazone) Complex CuII(atsm) Is Protective Against Cerebral Ischemia Through Modulation of the Inflammatory Milieu MT Huuskonen, Q Tuo, S Loppi, H Dhungana, P Korhonen, LE McInnes, ... Neurotherapeutics 14, 519-532, 2017 | 49 | 2017 |
| Neuroprotective copper bis (thiosemicarbazonato) complexes promote neurite elongation L Bica, JR Liddell, PS Donnelly, C Duncan, A Caragounis, I Volitakis, ... PLoS One 9 (2), e90070, 2014 | 49 | 2014 |
| Increased zinc and manganese in parallel with neurodegeneration, synaptic protein changes and activation of Akt/GSK3 signaling in ovine CLN6 neuronal ceroid lipofuscinosis KM Kanninen, A Grubman, J Meyerowitz, C Duncan, JL Tan, SJ Parker, ... PLoS One 8 (3), e58644, 2013 | 44 | 2013 |
