Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells Y Cordeaux, SJ Briddon, SPH Alexander, B Kellam, SJ Hill The FASEB Journal 22 (3), 850-860, 2008 | 208 | 2008 |
Kinetic analysis of antagonist-occupied adenosine-A3 receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and … R Corriden, LE Kilpatrick, B Kellam, SJ Briddon, SJ Hill The FASEB Journal 28 (10), 4211-4222, 2014 | 184 | 2014 |
The p85 subunit of phosphatidylinositol 3-kinase associates with the Fc receptor γ-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin JM Gibbins, S Briddon, A Shutes, MJ van Vugt, JGJ van de Winkel, T Saito, ... Journal of Biological Chemistry 273 (51), 34437-34443, 1998 | 176 | 1998 |
Quantitative analysis of the formation and diffusion of A1-adenosine receptor-antagonist complexes in single living cells SJ Briddon, RJ Middleton, Y Cordeaux, FM Flavin, JA Weinstein, ... Proceedings of the National Academy of Sciences 101 (13), 4673-4678, 2004 | 152 | 2004 |
Pharmacology under the microscope: the use of fluorescence correlation spectroscopy to determine the properties of ligand–receptor complexes SJ Briddon, SJ Hill Trends in pharmacological sciences 28 (12), 637-645, 2007 | 143 | 2007 |
Evidence for the involvement of p59fyn and p53/56lyn in collagen receptor signalling in human platelets SJ BRIDDON, SP WATSON Biochemical Journal 338 (1), 203-209, 1999 | 132 | 1999 |
New Fluorescent Adenosine A1-Receptor Agonists That Allow Quantification of Ligand−Receptor Interactions in Microdomains of Single Living Cells RJ Middleton, SJ Briddon, Y Cordeaux, AS Yates, CL Dale, MW George, ... Journal of medicinal chemistry 50 (4), 782-793, 2007 | 124 | 2007 |
Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands JG Baker, R Middleton, L Adams, LT May, SJ Briddon, B Kellam, SJ Hill British journal of pharmacology 159 (4), 772-786, 2010 | 116 | 2010 |
Influence of receptor number on functional responses elicited by agonists acting at the human adenosine A1 receptor: evidence for signaling pathway-dependent changes in agonist … Y Cordeaux, SJ Briddon, AE Megson, J McDonnell, JM Dickenson, SJ Hill Molecular pharmacology 58 (5), 1075-1084, 2000 | 113 | 2000 |
Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics LT May, LJ Bridge, LA Stoddart, SJ Briddon, SJ Hill The FASEB Journal 25 (10), 3465-3476, 2011 | 108 | 2011 |
Fragment screening at adenosine-A3 receptors in living cells using a fluorescence-based binding assay LA Stoddart, AJ Vernall, JL Denman, SJ Briddon, B Kellam, SJ Hill Chemistry & biology 19 (9), 1105-1115, 2012 | 105 | 2012 |
Probing the pharmacology of G protein-coupled receptors with fluorescent ligands LA Stoddart, LE Kilpatrick, SJ Briddon, SJ Hill Neuropharmacology 98, 48-57, 2015 | 101 | 2015 |
The LSM 510 META-ConfoCor 2 system: an integrated imaging and spectroscopic platform for single-molecule detection K Weisshart, V Jungel, SJ Briddon Current pharmaceutical biotechnology 5 (2), 135-154, 2004 | 84 | 2004 |
Studying GPCR pharmacology in membrane microdomains: fluorescence correlation spectroscopy comes of age SJ Briddon, LE Kilpatrick, SJ Hill Trends in pharmacological sciences 39 (2), 158-174, 2018 | 75 | 2018 |
Plasma membrane diffusion of G protein-coupled receptor oligomers SJ Briddon, J Gandía, OB Amaral, S Ferré, C Lluís, R Franco, SJ Hill, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (12), 2262-2268, 2008 | 66 | 2008 |
Development of novel fluorescent histamine H 1-receptor antagonists to study ligand-binding kinetics in living cells LA Stoddart, AJ Vernall, M Bouzo-Lorenzo, R Bosma, AJ Kooistra, ... Scientific reports 8 (1), 1572, 2018 | 64 | 2018 |
Plasma membrane dynamics and tetrameric organisation of ABCG2 transporters in mammalian cells revealed by single particle imaging techniques K Wong, SJ Briddon, ND Holliday, ID Kerr Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (1), 19-29, 2016 | 63 | 2016 |
A novel fluorescent histamine H1 receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands RH Rose, SJ Briddon, SJ Hill British journal of pharmacology 165 (6), 1789-1800, 2012 | 62 | 2012 |
The effect of allosteric modulators on the kinetics of agonist-G protein-coupled receptor interactions in single living cells LT May, TJ Self, SJ Briddon, SJ Hill Molecular pharmacology 78 (3), 511-523, 2010 | 61 | 2010 |
Syk and Fyn are required by mouse megakaryocytes for the rise in intracellular calcium induced by a collagen-related peptide SK Melford, M Turner, SJ Briddon, VLJ Tybulewicz, SP Watson Journal of Biological Chemistry 272 (44), 27539-27542, 1997 | 60 | 1997 |