Antigen-Presenting Intratumoral B Cells Affect CD4+ TIL Phenotypes in Non–Small Cell Lung Cancer Patients TC Bruno, PJ Ebner, BL Moore, OG Squalls, KA Waugh, EB Eruslanov, ... Cancer immunology research 5 (10), 898-907, 2017 | 224 | 2017 |
Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity P Araya, KA Waugh, KD Sullivan, NG Núñez, E Roselli, KP Smith, ... Proceedings of the National Academy of Sciences 116 (48), 24231-24241, 2019 | 103 | 2019 |
Mass cytometry reveals global immune remodeling with multi-lineage hypersensitivity to type I interferon in Down syndrome KA Waugh, P Araya, A Pandey, KR Jordan, KP Smith, RE Granrath, ... Cell reports 29 (7), 1893-1908. e4, 2019 | 98 | 2019 |
Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors RK Powers, R Culp-Hill, MP Ludwig, KP Smith, KA Waugh, R Minter, ... Nature communications 10 (1), 4766, 2019 | 82 | 2019 |
Molecular profile of tumor-specific CD8+ T cell hypofunction in a transplantable murine cancer model KA Waugh, SM Leach, BL Moore, TC Bruno, JD Buhrman, JE Slansky The journal of immunology 197 (4), 1477-1488, 2016 | 61 | 2016 |
JAK1 inhibition blocks lethal immune hypersensitivity in a mouse model of Down syndrome KD Tuttle, KA Waugh, P Araya, R Minter, DJ Orlicky, M Ludwig, Z Andrysik, ... Cell reports 33 (7), 2020 | 24 | 2020 |
Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model KA Waugh, R Minter, J Baxter, C Chi, MD Galbraith, KD Tuttle, ... Nature genetics 55 (6), 1034-1047, 2023 | 19 | 2023 |
Targeting transcriptional regulators of CD8+ T cell dysfunction to boost anti-tumor immunity KA Waugh, SM Leach, JE Slansky Vaccines 3 (3), 771-802, 2015 | 19 | 2015 |
Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibition MD Galbraith, AL Rachubinski, KP Smith, P Araya, KA Waugh, ... Science Advances 9 (26), eadg6218, 2023 | 10 | 2023 |
Tolerance of Tumor-Specific T cells in Melanoma Metastases KA Waugh, SM Leach, JE Slansky Journal of clinical & cellular immunology 7 (2), 2016 | 7 | 2016 |
Severely ill and high-risk COVID-19 patients exhibit increased peripheral circulation of CD62L+ and perforin+ T cells KE Lesteberg, P Araya, KA Waugh, L Chauhan, JM Espinosa, ... Frontiers in immunology 14, 1113932, 2023 | 2 | 2023 |