| Reversible histone glycation is associated with disease-related changes in chromatin architecture Q Zheng, ND Omans, R Leicher, A Osunsade, AS Agustinus, ... Nature Communications 10 (1), 1289, 2019 | 157 | 2019 |
| An enzymatic [4+ 2] cyclization cascade creates the pentacyclic core of pyrroindomycins Z Tian, P Sun, Y Yan, Z Wu, Q Zheng, S Zhou, H Zhang, F Yu, X Jia, ... Nature chemical biology 11 (4), 259-265, 2015 | 148 | 2015 |
| Multiplexing of combinatorial chemistry in antimycin biosynthesis: expansion of molecular diversity and utility Y Yan, J Chen, L Zhang, Q Zheng, Y Han, H Zhang, D Zhang, T Awakawa, ... Angewandte Chemie 125 (47), 12534-12538, 2013 | 94 | 2013 |
| Enzyme-dependent [4+ 2] cycloaddition depends on lid-like interaction of the N-terminal sequence with the catalytic core in PyrI4 Q Zheng, Y Guo, L Yang, Z Zhao, Z Wu, H Zhang, J Liu, X Cheng, J Wu, ... Cell chemical biology 23 (3), 352-360, 2016 | 78 | 2016 |
| Thiopeptide antibiotics exhibit a dual mode of action against intracellular pathogens by affecting both host and microbe Q Zheng, Q Wang, S Wang, J Wu, Q Gao, W Liu Chemistry & Biology 22 (8), 1002-1007, 2015 | 73 | 2015 |
| Non-enzymatic covalent modifications: a new link between metabolism and epigenetics Q Zheng, I Maksimovic, A Upad, Y David Protein & cell 11 (6), 401-416, 2020 | 69 | 2020 |
| Post-translational modifications involved in the biosynthesis of thiopeptide antibiotics Q Zheng, H Fang, W Liu Organic & Biomolecular Chemistry 15 (16), 3376-3390, 2017 | 53 | 2017 |
| Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation Q Zheng, A Osunsade, Y David Nature Communications 11 (1), 3241, 2020 | 52 | 2020 |
| An α/β-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization Q Zheng, S Wang, P Duan, R Liao, D Chen, W Liu Proceedings of the National Academy of Sciences 113 (50), 14318-14323, 2016 | 44 | 2016 |
| Precursor-directed mutational biosynthesis facilitates the functional assignment of two cytochromes P450 in thiostrepton biosynthesis Q Zheng, S Wang, R Liao, W Liu ACS Chemical Biology 11 (10), 2673-2678, 2016 | 41 | 2016 |
| Target-oriented design and biosynthesis of thiostrepton-derived thiopeptide antibiotics with improved pharmaceutical properties S Wang, Q Zheng, J Wang, Z Zhao, Q Li, Y Yu, R Wang, W Liu Organic Chemistry Frontiers 2 (2), 106-109, 2015 | 40 | 2015 |
| Recent advances in understanding the enzymatic reactions of [4+ 2] cycloaddition and spiroketalization Q Zheng, Z Tian, W Liu Current Opinion in Chemical Biology 31, 95-102, 2016 | 39 | 2016 |
| Rational control of polyketide extender units by structure‐based engineering of a crotonyl‐CoA carboxylase/reductase in antimycin biosynthesis L Zhang, T Mori, Q Zheng, T Awakawa, Y Yan, W Liu, I Abe Angewandte Chemie International Edition 54 (45), 13462-13465, 2015 | 35 | 2015 |
| Structural insights into a flavin-dependent [4+ 2] cyclase that catalyzes trans-decalin formation in pyrroindomycin biosynthesis Q Zheng, Y Gong, Y Guo, Z Zhao, Z Wu, Z Zhou, D Chen, L Pan, W Liu Cell chemical biology 25 (6), 718-727. e3, 2018 | 34 | 2018 |
| Bufospirostenin A and Bufogargarizin C, Steroids with Rearranged Skeletons from the Toad Bufo bufo gargarizans HY Tian, LJ Ruan, T Yu, QF Zheng, NH Chen, RB Wu, XQ Zhang, L Wang, ... Journal of Natural Products 80 (4), 1182-1186, 2017 | 34 | 2017 |
| (De) Toxifying the epigenetic code Q Zheng, NA Prescott, I Maksimovic, Y David Chemical research in toxicology 32 (5), 796-807, 2019 | 33 | 2019 |
| Insight into bicyclic thiopeptide biosynthesis benefited from development of a uniform approach for molecular engineering and production improvement H Guo, J Wang, Y Li, Y Yu, Q Zheng, J Wu, W Liu Chemical Science 5 (1), 240-246, 2014 | 33 | 2014 |
| Synthesis of an alkynyl methylglyoxal probe to investigate nonenzymatic histone glycation Q Zheng, I Maksimovic, A Upad, D Guber, Y David The Journal of organic chemistry 85 (3), 1691-1697, 2019 | 30 | 2019 |
| Chemo-enzymatic synthesis of equisetin X Li, Q Zheng, J Yin, W Liu, S Gao Chemical Communications 53 (34), 4695-4697, 2017 | 30 | 2017 |
| An azidoribose probe to track ketoamine adducts in histone ribose glycation I Maksimovic, Q Zheng, MN Trujillo, JJ Galligan, Y David Journal of the American Chemical Society 142 (22), 9999-10007, 2020 | 26 | 2020 |
Yael DavidAssociate Prof., Chemical Biology Program, MSKCC在 mskcc.org 的电子邮件经过验证
