Therapy-induced evolution of human lung cancer revealed by single-cell RNA sequencing A Maynard, CE McCoach, JK Rotow, L Harris, F Haderk, DL Kerr, ... Cell 182 (5), 1232-1251. e22, 2020 | 461 | 2020 |
Allosteric SHP2 inhibitors in cancer: Targeting the intersection of RAS, resistance, and the immune microenvironment DL Kerr, F Haderk, TG Bivona Current Opinion in Chemical Biology 62, 1-12, 2021 | 96 | 2021 |
AXL and error-prone DNA replication confer drug resistance and offer strategies to treat EGFR-mutant lung cancer A Noronha, N Belugali Nataraj, JS Lee, B Zhitomirsky, Y Oren, S Oster, ... Cancer discovery 12 (11), 2666-2683, 2022 | 56 | 2022 |
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance DR Caswell, P Gui, MK Mayekar, EK Law, O Pich, C Bailey, J Boumelha, ... Nature Genetics 56 (1), 60-73, 2024 | 42* | 2024 |
Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer S Nanjo, W Wu, N Karachaliou, CM Blakely, J Suzuki, YT Chou, SM Ali, ... The Journal of clinical investigation 132 (13), 2022 | 33 | 2022 |
Neoadjuvant osimertinib for the treatment of stage I-IIIA epidermal growth factor receptor–mutated non–small cell lung cancer: A phase II multicenter study CM Blakely, A Urisman, MA Gubens, CK Mulvey, GM Allen, SC Shiboski, ... Journal of Clinical Oncology, JCO. 24.00071, 2024 | 29* | 2024 |
Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells M Ali, M Lu, HX Ang, RS Soderquist, CE Eyler, HM Hutchinson, C Glass, ... Science translational medicine 14 (638), eabc7480, 2022 | 20 | 2022 |
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer F Haderk, YT Chou, L Cech, C Fernández-Méndez, J Yu, V Olivas, ... Nature Communications 15 (1), 3741, 2024 | 13 | 2024 |
Nitro Sulfonyl Fluorides are a new pharmacophore for the development of antibiotics C Sadlowski, B Park, CA Borges, S Das, DL Kerr, M He, H Han, L Riley, ... Molecular systems design & engineering 3 (4), 599-603, 2018 | 11 | 2018 |
A novel fluorescent surfactant enhances the delivery of the Cas9 ribonucleoprotein and enables the identification of edited cells J Li, JJ Røise, J Zhang, J Yang, DL Kerr, H Han, N Murthy Chemical Communications 55 (31), 4562-4565, 2019 | 10 | 2019 |
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors S Sinha, R Vegesna, S Mukherjee, AV Kammula, SR Dhruba, W Wu, ... Nature Cancer, 1-15, 2024 | 8* | 2024 |
Acid-Sensitive Surfactants Enhance the Delivery of Nucleic Acids JJ Røise, H Han, J Li, DL Kerr, C Taing, K Behrouzi, M He, E Ruan, ... Molecular Pharmaceutics 19 (1), 67–79, 2021 | 7 | 2021 |
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling S Hobor, M Al Bakir, CT Hiley, M Skrzypski, AM Frankell, B Bakker, ... Nature Communications 15 (1), 4871, 2024 | 3 | 2024 |
Deciphering the interplay of β-catenin/YAP signaling and alveolar lineage plasticity during targeted therapy in non-small cell lung cancer YT Chou, W Wu, D Kerr, M Slota, T Bivona Cancer Research 84 (6_Supplement), 2006-2006, 2024 | | 2024 |
CDK4 and CDK6 upregulation promotes DNA replication stress, genomic instability and resistance to EGFR targeted therapy in lung cancer B Gini, P Gui, W Wu, DL Kerr, L Tan, D Barbosa, V Olivas, C Gomez, ... bioRxiv, 2024.03. 12.584638, 2024 | | 2024 |
Deep learning-based characterization of the drug tolerant persister cell state in lung cancer. W Wu, L Cech, V Olivas, A Zaman, DL Kerr, TG Bivona JCO Global Oncology 9 (Supplement_1), 141-141, 2023 | | 2023 |
Single cell RNA sequencing reveals tumor immune microenvironment and T cell receptor diversity in epidermal growth factor receptor (EGFR) mutated lung cancer T Chakrabarti, W Wu, DL Kerr, P Allegakoen, TG Bivona, CM Blakely Cancer Research 83 (7_Supplement), 605-605, 2023 | | 2023 |
EP08. 02-147 Clinical Outcomes in Patients with or without Cell Cycle Gene Alterations in EGFR mutated Non-Small Cell Lung Cancer T Chakrabarti, DL Kerr, F Sun, R Lea, L Tan, W Wu, B Gini, T Bivona, ... Journal of Thoracic Oncology 17 (9), S473, 2022 | | 2022 |
Spatially resolved transcriptomics of cellular architecture in EGFR-mutated lung cancer DL Kerr, W Wu, W Tamaki, A Urisman, YT Chou, P Gui, DM Jablons, ... Cancer Research 82 (12_Supplement), 3808-3808, 2022 | | 2022 |
A self-immolative linker that releases thiols detects penicillin amidase and nitroreductase with high sensitivity via absorption spectroscopy EM Espinoza, JJ Røise, M He, IC Li, AK Agatep, P Udenyi, H Han, ... Chemical Communications 58 (19), 3166-3169, 2022 | | 2022 |