Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position JD Buenrostro, PG Giresi, LC Zaba, HY Chang, WJ Greenleaf Nature methods 10 (12), 1213-1218, 2013 | 5962 | 2013 |
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis RA Gupta, N Shah, KC Wang, J Kim, HM Horlings, DJ Wong, MC Tsai, ... nature 464 (7291), 1071-1076, 2010 | 5779 | 2010 |
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs JL Rinn, M Kertesz, JK Wang, SL Squazzo, X Xu, SA Brugmann, ... cell 129 (7), 1311-1323, 2007 | 5021 | 2007 |
Molecular mechanisms of long noncoding RNAs KC Wang, HY Chang Molecular cell 43 (6), 904-914, 2011 | 4684 | 2011 |
Genome regulation by long noncoding RNAs JL Rinn, HY Chang Annual review of biochemistry 81 (1), 145-166, 2012 | 4360 | 2012 |
Long noncoding RNA as modular scaffold of histone modification complexes MC Tsai, O Manor, Y Wan, N Mosammaparast, JK Wang, F Lan, Y Shi, ... Science 329 (5992), 689-693, 2010 | 3754 | 2010 |
Unique features of long non-coding RNA biogenesis and function JJ Quinn, HY Chang Nature reviews genetics 17 (1), 47-62, 2016 | 3386 | 2016 |
ATAC‐seq: a method for assaying chromatin accessibility genome‐wide JD Buenrostro, B Wu, HY Chang, WJ Greenleaf Current protocols in molecular biology 109 (1), 21.29. 1-21.29. 9, 2015 | 3194 | 2015 |
Long noncoding RNAs in cancer pathways AM Schmitt, HY Chang Cancer cell 29 (4), 452-463, 2016 | 2909 | 2016 |
Long noncoding RNAs: cellular address codes in development and disease PJ Batista, HY Chang Cell 152 (6), 1298-1307, 2013 | 2654 | 2013 |
Long noncoding RNAs and human disease O Wapinski, HY Chang Trends in cell biology 21 (6), 354-361, 2011 | 2184 | 2011 |
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression KC Wang, YW Yang, B Liu, A Sanyal, R Corces-Zimmerman, Y Chen, ... Nature 472 (7341), 120-124, 2011 | 2162 | 2011 |
Single-cell chromatin accessibility reveals principles of regulatory variation JD Buenrostro, B Wu, UM Litzenburger, D Ruff, ML Gonzales, MP Snyder, ... Nature 523 (7561), 486-490, 2015 | 2074 | 2015 |
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues MR Corces, AE Trevino, EG Hamilton, PG Greenside, ... Nature methods 14 (10), 959-962, 2017 | 1867 | 2017 |
Diversity, topographic differentiation, and positional memory in human fibroblasts HY Chang, JT Chi, S Dudoit, C Bondre, M Van De Rijn, D Botstein, ... Proceedings of the National Academy of Sciences 99 (20), 12877-12882, 2002 | 1396 | 2002 |
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters T Hung, Y Wang, MF Lin, AK Koegel, Y Kotake, GD Grant, HM Horlings, ... Nature genetics 43 (7), 621-629, 2011 | 1363 | 2011 |
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions C Chu, K Qu, FL Zhong, SE Artandi, HY Chang Molecular cell 44 (4), 667-678, 2011 | 1336 | 2011 |
Daxx, a novel Fas-binding protein that activates JNK and apoptosis X Yang, R Khosravi-Far, HY Chang, D Baltimore Cell 89 (7), 1067-1076, 1997 | 1283 | 1997 |
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin E Michishita, RA McCord, E Berber, M Kioi, H Padilla-Nash, M Damian, ... Nature 452 (7186), 492-496, 2008 | 1254 | 2008 |
SIRT6 links histone H3 lysine 9 deacetylation to NF-κB-dependent gene expression and organismal life span TLA Kawahara, E Michishita, AS Adler, M Damian, E Berber, M Lin, ... Cell 136 (1), 62-74, 2009 | 1225 | 2009 |