Azapeptides and their therapeutic potential C Proulx, D Sabatino, R Hopewell, J Spiegel, Y García Ramos, WD Lubell Future medicinal chemistry 3 (9), 1139-1164, 2011 | 192 | 2011 |
18F-MK-6240 PET for early and late detection of neurofibrillary tangles TA Pascoal, J Therriault, AL Benedet, M Savard, FZ Lussier, M Chamoun, ... Brain 143 (9), 2818-2830, 2020 | 185 | 2020 |
In vivo quantification of neurofibrillary tangles with [18F]MK-6240 TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ... Alzheimer's research & therapy 10, 1-14, 2018 | 154 | 2018 |
Syntheses and evaluation of carbon-11-and fluorine-18-radiolabeled pan-tropomyosin receptor kinase (Trk) inhibitors: exploration of the 4-aza-2-oxindole scaffold as Trk PET … V Bernard-Gauthier, A Aliaga, A Aliaga, M Boudjemeline, R Hopewell, ... ACS Chemical Neuroscience 6 (2), 260-276, 2015 | 31 | 2015 |
[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease TA Pascoal, M Chamoun, E Lax, HY Wey, M Shin, KP Ng, MS Kang, ... nature communications 13 (1), 4171, 2022 | 20 | 2022 |
N-Aminoimidazolidin-2-one Peptidomimetics ND Doan, R Hopewell, WD Lubell Organic letters 16 (8), 2232-2235, 2014 | 19 | 2014 |
Characterization of scintillating fibers for use as positron detector in positron emission tomography V Turgeon, G Kertzscher, L Carroll, R Hopewell, G Massarweh, SA Enger Physica Medica 65, 114-120, 2019 | 17 | 2019 |
Highly efficient solid phase supported radiosynthesis of [11C]PiB using tC18 cartridge as a “3‐in‐1” production entity M Boudjemeline, R Hopewell, PL Rochon, D Jolly, I Hammami, ... Journal of Labelled Compounds and Radiopharmaceuticals 60 (14), 632-638, 2017 | 14 | 2017 |
CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals J Simrén, WS Brum, NJ Ashton, AL Benedet, TK Karikari, H Kvartsberg, ... Alzheimer's Research & Therapy 14 (1), 192, 2022 | 13 | 2022 |
MCEF is localized to the nucleus by protein sequences encoded within three distinct exons, where it represses HIV-1 Tat-transactivation of LTR-directed transcription MF Niedzielski, R Hopewell, Z Ismail, MC Estable International journal of biological sciences 3 (4), 225, 2007 | 13 | 2007 |
1H-Pyrroles W Lubell, D Saint-Cyr, J Dufour-Gallant, R Hopewell, N Boutard, ... Science of Synthesis 1, 157-388, 2013 | 12 | 2013 |
Co-registration of imaging modalities (MRI, CT and PET) to perform frameless stereotaxic robotic injections in the common marmoset C Kwan, MS Kang, SG Nuara, JC Gourdon, D Bédard, CL Tardif, ... Neuroscience 480, 143-154, 2022 | 10 | 2022 |
A simplified radiosynthesis of [18F]MK‐6240 for tau PET imaging R Hopewell, K Ross, A Kostikov, TA Pascoal, T Alberti, ... Journal of Labelled Compounds and Radiopharmaceuticals 62 (2), 109-114, 2019 | 10 | 2019 |
In vivo quantification of neurofibrillary tangles with [(18) F] MK-6240. Alzheimers Res Ther 10: 74 TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ... | 10 | 2018 |
Development of “[11C] kits” for a fast, efficient and reliable production of carbon-11 labeled radiopharmaceuticals for Positron Emission Tomography D Jolly, R Hopewell, M Kovacevic, QY Li, JP Soucy, A Kostikov Applied radiation and isotopes 121, 76-81, 2017 | 8 | 2017 |
Preliminary Evaluations of [11C]Verubulin: Implications for Microtubule Imaging With PET A Lindberg, AV Mossine, A Aliaga, R Hopewell, G Massarweh, ... Frontiers in Neuroscience 15, 725873, 2021 | 6 | 2021 |
Cryo-EM structure of Alzheimer’s disease tau filaments with PET ligand MK-6240 P Kunach, J Vaquer-Alicea, MS Smith, R Hopewell, J Monistrol, L Moquin, ... BioRxiv, 2023 | 5 | 2023 |
Distribution of [11C]-JNJ-42491293 in the marmoset brain: a positron emission tomography study MS Kang, A Hamadjida, D Bédard, SG Nuara, JC Gourdon, S Frey, ... Naunyn-Schmiedeberg's Archives of Pharmacology 396 (9), 2095-2103, 2023 | 2 | 2023 |
Solid Phase 11C-Methylation, Purification and Formulation for the Production of PET Tracers TA Singleton, M Boudjemeline, R Hopewell, D Jolly, H Bdair, A Kostikov JoVE (Journal of Visualized Experiments), e60237, 2019 | 1 | 2019 |
Peptidomimetics comprising N-amino cyclic urea residues and uses thereof WD Lubell, S Chemtob, H Ong, R Hopewell, C Proulx, K Beauregard, ... US Patent 8,993,515, 2015 | 1 | 2015 |