The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCFβ-TrCP E3 ligase CY Liu, ZY Zha, X Zhou, H Zhang, W Huang, D Zhao, T Li, SW Chan, ... Journal of Biological Chemistry 285 (48), 37159-37169, 2010 | 588 | 2010 |
A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells SW Chan, CJ Lim, K Guo, CP Ng, I Lee, W Hunziker, Q Zeng, W Hong Cancer research 68 (8), 2592-2598, 2008 | 555 | 2008 |
Hippo pathway-independent restriction of TAZ and YAP by angiomotin SW Chan, CJ Lim, YF Chong, AV Pobbati, C Huang, W Hong Journal of Biological Chemistry 286 (9), 7018-7026, 2011 | 421 | 2011 |
TEADs mediate nuclear retention of TAZ to promote oncogenic transformation SW Chan, CJ Lim, LS Loo, YF Chong, C Huang, W Hong Journal of Biological Chemistry 284 (21), 14347-14358, 2009 | 267 | 2009 |
AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma MZ Xu, SW Chan, AM Liu, KF Wong, ST Fan, J Chen, RT Poon, L Zender, ... Oncogene 30 (10), 1229-1240, 2011 | 261 | 2011 |
Structural basis of YAP recognition by TEAD4 in the hippo pathway L Chen, SW Chan, XQ Zhang, M Walsh, CJ Lim, W Hong, H Song Genes & development 24 (3), 290-300, 2010 | 257 | 2010 |
The Hippo pathway in biological control and cancer development SW Chan, CJ Lim, L Chen, YF Chong, C Huang, H Song, W Hong Journal of cellular physiology 226 (4), 928-939, 2011 | 197 | 2011 |
Structural and functional similarity between the Vgll1-TEAD and the YAP-TEAD complexes AV Pobbati, SW Chan, I Lee, H Song, W Hong Structure 20 (7), 1135-1140, 2012 | 169 | 2012 |
WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ SW Chan, CJ Lim, C Huang, YF Chong, HJ Gunaratne, KA Hogue, ... Oncogene 30 (5), 600-610, 2011 | 114 | 2011 |
Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation C Lorthongpanich, DM Messerschmidt, SW Chan, W Hong, BB Knowles, ... Genes & development 27 (13), 1441-1446, 2013 | 113 | 2013 |
Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex HYK Kaan, SW Chan, SKJ Tan, F Guo, CJ Lim, W Hong, H Song Scientific reports 7 (1), 2035, 2017 | 111 | 2017 |
Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation SW Chan, CJ Lim, F Guo, I Tan, T Leung, W Hong Journal of Biological Chemistry 288 (52), 37296-37307, 2013 | 110 | 2013 |
Histone demethylase RBP2 is critical for breast cancer progression and metastasis J Cao, Z Liu, WKC Cheung, M Zhao, SY Chen, SW Chan, CJ Booth, ... Cell reports 6 (5), 868-877, 2014 | 104 | 2014 |
Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated transcription SW Chan, W Hong Journal of Biological Chemistry 276 (30), 28402-28412, 2001 | 102 | 2001 |
Deubiquitinating enzyme USP9X suppresses tumor growth via LATS kinase and core components of the hippo pathway A Toloczko, F Guo, HF Yuen, Q Wen, SA Wood, YS Ong, PY Chan, ... Cancer research 77 (18), 4921-4933, 2017 | 85 | 2017 |
Wnt signaling promotes breast cancer by blocking ITCH-mediated degradation of YAP/TAZ transcriptional coactivator WBP2 SK Lim, SY Lu, SA Kang, HJ Tan, Z Li, ZN Adrian Wee, JS Guan, ... Cancer Research 76 (21), 6278-6289, 2016 | 74 | 2016 |
MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells CY Liu, SW Chan, F Guo, A Toloczko, L Cui, W Hong Oncotarget 7 (12), 13706, 2016 | 36 | 2016 |
Unusual amino acid determinants of host range in the Mtx2 family of mosquitocidal toxins SW Chan, T Thanabalu, BY Wee, AG Porter Journal of Biological Chemistry 271 (24), 14183-14187, 1996 | 36 | 1996 |
VHZ is a novel centrosomal phosphatase associated with cell growth and human primary cancers JP Tang, CP Tan, J Li, MM Siddique, K Guo, SW Chan, JE Park, WN Tay, ... Molecular cancer 9, 1-9, 2010 | 28 | 2010 |
Retinoblastoma protein is functionally distinct from its homologues in affecting glucocorticoid receptor-mediated transcription and apoptosis P Singh, SW Chan, W Hong Journal of Biological Chemistry 276 (17), 13762-13770, 2001 | 24 | 2001 |