Membrane-proximal epitope facilitates efficient T cell synapse formation by anti-FcRH5/CD3 and is a requirement for myeloma cell killing J Li, NJ Stagg, J Johnston, MJ Harris, SA Menzies, D DiCara, V Clark, ... Cancer cell 31 (3), 383-395, 2017 | 266 | 2017 |
Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action S Sukumaran, RR Almon, DC DuBois, WJ Jusko Advanced drug delivery reviews 62 (9-10), 904-917, 2010 | 184 | 2010 |
An anti-CD3/anti–CLL-1 bispecific antibody for the treatment of acute myeloid leukemia SR Leong, S Sukumaran, M Hristopoulos, K Totpal, S Stainton, E Lu, ... Blood, The Journal of the American Society of Hematology 129 (5), 609-618, 2017 | 173 | 2017 |
An allosteric anti-tryptase antibody for the treatment of mast cell-mediated severe asthma HR Maun, JK Jackman, DF Choy, KM Loyet, TL Staton, G Jia, A Dressen, ... Cell 179 (2), 417-431. e19, 2019 | 90 | 2019 |
Light-dark oscillations in the lung transcriptome: implications for lung homeostasis, repair, metabolism, disease, and drug action S Sukumaran, WJ Jusko, DC DuBois, RR Almon Journal of applied physiology 110 (6), 1732-1747, 2011 | 84 | 2011 |
Circadian rhythms: influence on physiology, pharmacology, and therapeutic interventions VS Ayyar, S Sukumaran Journal of pharmacokinetics and pharmacodynamics 48, 321-338, 2021 | 75 | 2021 |
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis T Sun, Z Huang, WC Liang, J Yin, WY Lin, J Wu, JM Vernes, J Lutman, ... Science translational medicine 13 (605), eabe0407, 2021 | 68 | 2021 |
Adipose tissue deficiency and chronic inflammation in diabetic Goto-Kakizaki rats B Xue, S Sukumaran, J Nie, WJ Jusko, DC DuBois, RR Almon PLoS one 6 (2), e17386, 2011 | 67 | 2011 |
Circadian variations in gene expression in rat abdominal adipose tissue and relationship to physiology S Sukumaran, B Xue, WJ Jusko, DC DuBois, RR Almon Physiological genomics 42 (2), 141-152, 2010 | 66 | 2010 |
Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases EG Stefanich, J Rae, S Sukumaran, J Lutman, A Lekkerkerker, W Ouyang, ... Biochemical Pharmacology 152, 224-235, 2018 | 53 | 2018 |
Mechanism-based pharmacokinetic/pharmacodynamic model for THIOMAB™ drug conjugates S Sukumaran, K Gadkar, C Zhang, S Bhakta, L Liu, K Xu, H Raab, SF Yu, ... Pharmaceutical research 32, 1884-1893, 2015 | 51 | 2015 |
An in vitro FcRn- dependent transcytosis assay as a screening tool for predictive assessment of nonspecific clearance of antibody therapeutics in humans S Chung, V Nguyen, YL Lin, J Lafrance-Vanasse, SJ Scales, K Lin, ... MAbs 11 (5), 942-955, 2019 | 46 | 2019 |
Glucocorticoid effects on adiponectin expression S Sukumaran, DC DuBois, WJ Jusko, RR Almon Vitamins & Hormones 90, 163-186, 2012 | 46 | 2012 |
Evidence for a glucocorticoid receptor beta splice variant in the rat and its physiological regulation in liver DC DuBois, S Sukumaran, WJ Jusko, RR Almon Steroids 78 (2), 312-320, 2013 | 44 | 2013 |
Highly multiplexed and reproducible ion-current-based strategy for large-scale quantitative proteomics and the application to protein expression dynamics induced by … E Nouri-Nigjeh, S Sukumaran, C Tu, J Li, X Shen, X Duan, DC DuBois, ... Analytical chemistry 86 (16), 8149-8157, 2014 | 42 | 2014 |
Differential muscle gene expression as a function of disease progression in Goto-Kakizaki diabetic rats J Nie, B Xue, S Sukumaran, WJ Jusko, DC DuBois, RR Almon Molecular and cellular endocrinology 338 (1-2), 10-17, 2011 | 40 | 2011 |
Mechanistic modeling of the effects of glucocorticoids and circadian rhythms on adipokine expression S Sukumaran, WJ Jusko, DC DuBois, RR Almon Journal of Pharmacology and Experimental Therapeutics 337 (3), 734-746, 2011 | 35 | 2011 |
A PK/PD analysis of circulating biomarkers and their relationship to tumor response in atezolizumab‐treated non‐small cell lung cancer patients I Netterberg, CC Li, L Molinero, N Budha, S Sukumaran, M Stroh, ... Clinical Pharmacology & Therapeutics 105 (2), 486-495, 2019 | 34 | 2019 |
Circadian signatures in rat liver: from gene expression to pathways MA Ovacik, S Sukumaran, RR Almon, DC DuBois, WJ Jusko, ... BMC bioinformatics 11, 1-15, 2010 | 33 | 2010 |
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members Y Yang, SH Yeh, S Madireddi, WL Matochko, C Gu, P Pacheco Sanchez, ... MAbs 11 (6), 996-1011, 2019 | 31 | 2019 |