Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis A Gruzman, WL Wood, E Alpert, MD Prasad, RG Miller, JD Rothstein, ... Proceedings of the National Academy of Sciences 104 (30), 12524-12529, 2007 | 234 | 2007 |
Adenosine monophosphate-activated protein kinase (AMPK) as a new target for antidiabetic drugs: a review on metabolic, pharmacological and chemical considerations A Gruzman, G Babai, S Sasson The review of diabetic studies: RDS 6 (1), 13, 2009 | 152 | 2009 |
Novel compounds targeting the mitochondrial protein VDAC1 inhibit apoptosis and protect against mitochondrial dysfunction D Ben-Hail, R Begas-Shvartz, M Shalev, A Shteinfer-Kuzmine, A Gruzman, ... Journal of Biological Chemistry 291 (48), 24986-25003, 2016 | 107 | 2016 |
Synthesis and mechanism of hypoglycemic activity of benzothiazole derivatives E Meltzer-Mats, G Babai-Shani, L Pasternak, N Uritsky, T Getter, O Viskind, ... Journal of medicinal chemistry 56 (13), 5335-5350, 2013 | 94 | 2013 |
The roles of hyperglycaemia and oxidative stress in the rise and collapse of the natural protective mechanism against vascular endothelial cell dysfunction in diabetes G Cohen, Y Riahi, E Alpert, A Gruzman, S Sasson Archives of physiology and biochemistry 113 (4-5), 259-267, 2007 | 89 | 2007 |
A natural protective mechanism against hyperglycaemia in vascular endothelial and smooth-muscle cells: role of glucose and 12-hydroxyeicosatetraenoic acid E Alpert, A Gruzman, H Totary, N Kaiser, R Reich, S Sasson Biochemical journal 362 (2), 413-422, 2002 | 84 | 2002 |
Synthesis and characterization of new and potent α-lipoic acid derivatives A Gruzman, A Hidmi, J Katzhendler, A Haj-Yehie, S Sasson Bioorganic & medicinal chemistry 12 (5), 1183-1190, 2004 | 82 | 2004 |
The Natural Protective Mechanism Against Hyperglycemia in Vascular Endothelial Cells: Roles of the Lipid Peroxidation Product 4-Hydroxydodecadienal and Peroxisome Proliferator … Y Riahi, Y Sin-Malia, G Cohen, E Alpert, A Gruzman, J Eckel, B Staels, ... Diabetes 59 (4), 808-818, 2010 | 78 | 2010 |
Delayed autoregulation of glucose transport in vascular endothelial cells E Alpert, A Gruzman, Y Riahi, R Blejter, P Aharoni, G Weisinger, J Eckel, ... Diabetologia 48, 752-755, 2005 | 75 | 2005 |
Amelioration of TNBS-induced colon inflammation in rats by phospholipase A2 inhibitor M Krimsky, S Yedgar, L Aptekar, O Schwob, G Goshen, A Gruzman, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 285 (3 …, 2003 | 72 | 2003 |
A DJ-1 based peptide attenuates dopaminergic degeneration in mice models of Parkinson's disease via enhancing Nrf2 N Lev, Y Barhum, T Ben-Zur, I Aharony, L Trifonov, N Regev, E Melamed, ... PLoS One 10 (5), e0127549, 2015 | 45 | 2015 |
Novel d-Xylose Derivatives Stimulate Muscle Glucose Uptake by Activating AMP-Activated Protein Kinase α A Gruzman, O Shamni, M Ben Yakir, D Sandovski, A Elgart, E Alpert, ... Journal of medicinal chemistry 51 (24), 8096-8108, 2008 | 45 | 2008 |
Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation B Daniel, O Green, O Viskind, A Gruzman Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14 (5-6), 434-443, 2013 | 33 | 2013 |
4-Hydroxy tempol-induced impairment of mitochondrial function and augmentation of glucose transport in vascular endothelial and smooth muscle cells E Alpert, H Altman, H Totary, A Gruzman, D Barnea, V Barash, S Sasson Biochemical pharmacology 67 (10), 1985-1995, 2004 | 33 | 2004 |
Pruritus in psoriasis and atopic dermatitis: current treatments and new perspectives S Kahremany, L Hofmann, M Harari, A Gruzman, G Cohen Pharmacological Reports 73 (2), 443-453, 2021 | 29 | 2021 |
Eicosanoids participate in the regulation of cardiac glucose transport by contribution to a rearrangement of actin cytoskeletal elements O DRANSFELD, I RAKATZI, S SASSON, A GRUZMAN, M SCHMITT, ... Biochemical Journal 359 (1), 47-54, 2001 | 29 | 2001 |
Advances in understanding the initial steps of pruritoceptive itch: how the itch hits the switch S Kahremany, L Hofmann, A Gruzman, G Cohen International journal of molecular sciences 21 (14), 4883, 2020 | 28 | 2020 |
Activation of PPAR δ: from computer modelling to biological effects S Kahremany, A Livne, A Gruzman, H Senderowitz, S Sasson British journal of pharmacology 172 (3), 754-770, 2015 | 26 | 2015 |
A chemical chaperone‐based drug candidate is effective in a mouse model of amyotrophic lateral sclerosis (ALS) T Getter, I Zaks, Y Barhum, T Ben‐Zur, S Böselt, S Gregoire, O Viskind, ... ChemMedChem 10 (5), 850-861, 2015 | 25 | 2015 |
Novel inhibitors of leukocyte transendothelial migration T Getter, R Margalit, S Kahremany, L Levy, E Blum, N Khazanov, ... Bioorganic chemistry 92, 103250, 2019 | 22 | 2019 |