Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord KA Kigerl, JC Gensel, DP Ankeny, JK Alexander, DJ Donnelly, ... Journal of Neuroscience 29 (43), 13435-13444, 2009 | 2419 | 2009 |
Macrophage activation and its role in repair and pathology after spinal cord injury JC Gensel, B Zhang Brain research 1619, 1-11, 2015 | 779 | 2015 |
Spinal cord injury scarring and inflammation: therapies targeting glial and inflammatory responses MB Orr, JC Gensel Neurotherapeutics 15 (3), 541-553, 2018 | 492 | 2018 |
Immune activation promotes depression 1 month after diffuse brain injury: a role for primed microglia AM Fenn, JC Gensel, Y Huang, PG Popovich, J Lifshitz, JP Godbout Biological psychiatry 76 (7), 575-584, 2014 | 291 | 2014 |
Behavioral and histological characterization of unilateral cervical spinal cord contusion injury in rats JC Gensel, CA Tovar, FPT Hamers, RJ Deibert, MS Beattie, ... Journal of neurotrauma 23 (1), 36-54, 2006 | 287 | 2006 |
Cell death after spinal cord injury is exacerbated by rapid TNFα-induced trafficking of GluR2-lacking AMPARs to the plasma membrane AR Ferguson, RN Christensen, JC Gensel, BA Miller, F Sun, EC Beattie, ... Journal of Neuroscience 28 (44), 11391-11400, 2008 | 272 | 2008 |
Macrophages promote axon regeneration with concurrent neurotoxicity JC Gensel, S Nakamura, Z Guan, N van Rooijen, DP Ankeny, ... Journal of Neuroscience 29 (12), 3956-3968, 2009 | 253 | 2009 |
Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury. FAR Nielson JL, Paquette J, Liu AW, Guandique CF, Tovar CA, Inoue T, Irvine ... Nat Commun 14 (6), 8581, 2015 | 225* | 2015 |
IL-4 signaling drives a unique arginase+/IL-1β+ microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Rα after … AM Fenn, JCE Hall, JC Gensel, PG Popovich, JP Godbout Journal of Neuroscience 34 (26), 8904-8917, 2014 | 222 | 2014 |
Microglia and macrophage metabolism in CNS injury and disease: The role of immunometabolism in neurodegeneration and neurotrauma NA Devanney, AN Stewart, JC Gensel Experimental neurology 329, 113310, 2020 | 197 | 2020 |
Macrophages are necessary for epimorphic regeneration in African spiny mice J Simkin, TR Gawriluk, JC Gensel, AW Seifert Elife 6, e24623, 2017 | 173 | 2017 |
Acute transplantation of glial-restricted precursor cells into spinal cord contusion injuries: survival, differentiation, and effects on lesion environment and axonal regeneration CE Hill, C Proschel, M Noble, M Mayer-Proschel, JC Gensel, MS Beattie, ... Experimental neurology 190 (2), 289-310, 2004 | 173 | 2004 |
Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment JC Gensel, TJ Kopper, B Zhang, MB Orr, WM Bailey Scientific reports 7 (1), 40144, 2017 | 156 | 2017 |
An efficient and reproducible method for quantifying macrophages in different experimental models of central nervous system pathology DJ Donnelly, JC Gensel, DP Ankeny, N van Rooijen, PG Popovich Journal of neuroscience methods 181 (1), 36-44, 2009 | 149 | 2009 |
Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injury B Zhang, WM Bailey, KJ Braun, JC Gensel Experimental neurology 273, 83-91, 2015 | 136 | 2015 |
Myelin as an inflammatory mediator: Myelin interactions with complement, macrophages, and microglia in spinal cord injury TJ Kopper, JC Gensel Journal of neuroscience research 96 (6), 969-977, 2018 | 114 | 2018 |
Large animal and primate models of spinal cord injury for the testing of novel therapies BK Kwon, F Streijger, CE Hill, AJ Anderson, M Bacon, MS Beattie, ... Experimental neurology 269, 154-168, 2015 | 113 | 2015 |
Is neuroinflammation in the injured spinal cord different than in the brain? Examining intrinsic differences between the brain and spinal cord B Zhang, JC Gensel Experimental neurology 258, 112-120, 2014 | 104 | 2014 |
Age increases reactive oxygen species production in macrophages and potentiates oxidative damage after spinal cord injury B Zhang, WM Bailey, AL McVicar, JC Gensel Neurobiology of Aging 47, 157-167, 2016 | 96 | 2016 |
Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury B Zhang, WM Bailey, TJ Kopper, MB Orr, DJ Feola, JC Gensel Journal of neuroinflammation 12 (1), 218, 2015 | 95 | 2015 |