Cancer stem cells: the architects of the tumor ecosystem BC Prager, Q Xie, S Bao, JN Rich cell stem cell 24 (1), 41-53, 2019 | 465 | 2019 |
Mitochondrial control by DRP1 in brain tumor initiating cells Q Xie, Q Wu, CM Horbinski, WA Flavahan, K Yang, W Zhou, ... Nature neuroscience 18 (4), 501-510, 2015 | 373 | 2015 |
N6-methyladenine DNA modification in glioblastoma Q Xie, TP Wu, RC Gimple, Z Li, BC Prager, Q Wu, Y Yu, P Wang, Y Wang, ... Cell 175 (5), 1228-1243. e20, 2018 | 258 | 2018 |
The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells D Dixit, BC Prager, RC Gimple, HX Poh, Y Wang, Q Wu, Z Qiu, RL Kidwell, ... Cancer discovery 11 (2), 480-499, 2021 | 253 | 2021 |
Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions M Tang, Q Xie, RC Gimple, Z Zhong, T Tam, J Tian, RL Kidwell, Q Wu, ... Cell research 30 (10), 833-853, 2020 | 200 | 2020 |
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma TE Miller, BB Liau, LC Wallace, AR Morton, Q Xie, D Dixit, DC Factor, ... Nature 547 (7663), 355-359, 2017 | 197 | 2017 |
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJY Kim, BC Prager, ... Nature neuroscience 20 (5), 661-673, 2017 | 178 | 2017 |
YAP/TEAD–mediated transcription controls cellular senescence Q Xie, J Chen, H Feng, S Peng, U Adams, Y Bai, L Huang, J Li, J Huang, ... Cancer research 73 (12), 3615-3624, 2013 | 169 | 2013 |
Glioma Stem Cell Specific Super Enhancer Promotes Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling RC Gimple, RL Kidwell, LJY Kim, T Sun, AD Gromovsky, Q Wu, M Wolf, ... Cancer discovery, CD-19-0061, 2019 | 143 | 2019 |
Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination X Fang, W Zhou, Q Wu, Z Huang, Y Shi, K Yang, C Chen, Q Xie, SC Mack, ... Journal of Experimental Medicine 214 (1), 245-267, 2017 | 137 | 2017 |
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2 Q Lu, J Liu, S Zhao, MFG Castro, M Laurent-Rolle, J Dong, X Ran, ... Immunity 54 (6), 1304-1319. e9, 2021 | 135 | 2021 |
Lysine methylation of FOXO3 regulates oxidative stress‐induced neuronal cell death Q Xie, Y Hao, L Tao, S Peng, C Rao, H Chen, H You, M Dong, Z Yuan EMBO reports 13 (4), 371-377, 2012 | 114 | 2012 |
MYC-regulated mevalonate metabolism maintains brain tumor–initiating cells X Wang, Z Huang, Q Wu, BC Prager, SC Mack, K Yang, LJY Kim, ... Cancer research 77 (18), 4947-4960, 2017 | 110 | 2017 |
MST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylation F Yuan, Q Xie, J Wu, Y Bai, B Mao, Y Dong, W Bi, G Ji, W Tao, Y Wang, ... Journal of biological chemistry 286 (9), 6940-6945, 2011 | 102 | 2011 |
CRISPR screening of CAR T cells and cancer stem cells reveals critical dependencies for cell-based therapies D Wang, BC Prager, RC Gimple, B Aguilar, D Alizadeh, H Tang, D Lv, ... Cancer discovery 11 (5), 1192-1211, 2021 | 99 | 2021 |
c-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82 W Bi, L Xiao, Y Jia, J Wu, Q Xie, J Ren, G Ji, Z Yuan Journal of biological chemistry 285 (9), 6259-6264, 2010 | 81 | 2010 |
Post-translational regulation of FOXO Q Xie, J Chen, Z Yuan Acta Biochim Biophys Sin 44 (11), 897-901, 2012 | 75 | 2012 |
Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase Z Xia, M Tang, J Ma, H Zhang, RC Gimple, BC Prager, H Tang, C Sun, ... Nucleic Acids Research 49 (13), 7361-7374, 2021 | 69 | 2021 |
Methylation-mediated regulation of E2F1 in DNA damage-induced cell death Q Xie, Y Bai, J Wu, Y Sun, Y Wang, Y Zhang, P Mei, Z Yuan Journal of Receptors and Signal Transduction 31 (2), 139-146, 2011 | 64 | 2011 |
CDC20 maintains tumor initiating cells Q Xie, Q Wu, SC Mack, K Yang, L Kim, CG Hubert, WA Flavahan, C Chu, ... Oncotarget, 2015 | 57 | 2015 |