Pharmacological activities of natural triterpenoids and their therapeutic implications P Dzubak, M Hajduch, D Vydra, A Hustova, M Kvasnica, D Biedermann, ... Natural product reports 23 (3), 394-411, 2006 | 898 | 2006 |
Synthesis of A-seco derivatives of betulinic acid with cytotoxic activity M Urban, J Sarek, J Klinot, G Korinkova, M Hajduch Journal of Natural Products 67 (7), 1100-1105, 2004 | 188 | 2004 |
Pentacyclic triterpenoids with nitrogen- and sulfur-containing heterocycles: synthesis and medicinal significance M Kvasnica, M Urban, NJ Dickinson, J Sarek Natural Product reports 32 (9), 1303 - 1330, 2015 | 147 | 2015 |
Triterpenoid pyrazines and benzopyrazines with cytotoxic activity M Urban, J Sarek, M Kvasnica, I Tislerova, M Hajduch Journal of natural products 70 (4), 526-532, 2007 | 98 | 2007 |
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research J Hodon, L Borkova, J Pokorny, A Kazakova, M Urban European journal of medicinal chemistry 182, 111653, 2019 | 94 | 2019 |
Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid M Urban, M Vlk, P Dzubak, M Hajduch, J Sarek Bioorganic & medicinal chemistry 20 (11), 3666-3674, 2012 | 91 | 2012 |
New modular and efficient approach to 6-substituted pyridin-2-yl C-nucleosides M Urban, R Pohl, B Klepetářová, M Hocek The Journal of Organic Chemistry 71 (19), 7322-7328, 2006 | 64 | 2006 |
Influence of esterification and modification of A-ring in a group of lupane acids on their cytotoxicity M Urban, J Sarek, I Tislerova, P Dzubak, M Hajduch Bioorganic & medicinal chemistry 13 (19), 5527-5535, 2005 | 63 | 2005 |
Incorporation of the fluorescent ribonucleotide analogue tCTP by T7 RNA polymerase G Stengel, M Urban, BW Purse, RD Kuchta Analytical chemistry 82 (3), 1082-1089, 2010 | 57 | 2010 |
A synthetic approach for the rapid preparation of BODIPY conjugates and their use in imaging of cellular drug uptake and distribution S Krajcovicova, J Stankova, P Dzubak, M Hajduch, M Soural, M Urban Chemistry–A European Journal 24 (19), 4957-4966, 2018 | 51 | 2018 |
Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid L Borkova, I Frydrych, N Jakubcová, R Adamek, B Lišková, S Gurská, ... European Journal of Medicinal Chemistry 185, 111806, 2020 | 45 | 2020 |
Cytotoxic conjugates of betulinic acid and substituted triazoles prepared by Huisgen Cycloaddition from 30-azidoderivatives V Sidova, P Zoufaly, J Pokorny, P Dzubak, M Hajduch, I Popa, M Urban PLoS One 12 (2), e0171621, 2017 | 45 | 2017 |
Ambivalent incorporation of the fluorescent cytosine analogues tC and tCo by human DNA polymerase α and Klenow fragment G Stengel, BW Purse, LM Wilhelmsson, M Urban, RD Kuchta Biochemistry 48 (31), 7547-7555, 2009 | 45 | 2009 |
Correlation of cytotoxic activity of betulinines and their hydroxy analogues J Sarek, M Kvasnica, M Urban, J Klinot, M Hajduch Bioorganic & medicinal chemistry letters 15 (19), 4196-4200, 2005 | 45 | 2005 |
Click reactions in chemistry of triterpenes-advances towards development of potential therapeutics J Pokorny, L Borkova, M Urban Current Medicinal Chemistry 25 (5), 636-658, 2018 | 44 | 2018 |
Synthesis of betulinic acid derivatives with modified a‐rings and their application as potential drug candidates L Borkova, J Hodon, M Urban Asian Journal of Organic Chemistry 7 (8), 1542-1560, 2018 | 43 | 2018 |
The potential of triterpenoids in the treatment of melanoma J Sarek, M Kvasnica, M Vlk, M Urban, P Dzubak, M Hajduch Research on Melanoma: A Glimpse into Current Directions and Future Trends …, 2011 | 42 | 2011 |
Synthesis of cytotoxic 2, 2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells L Borkova, L Jasikova, J Rehulka, K Frisonsova, M Urban, I Frydrych, ... European Journal of Medicinal Chemistry 96, 482-490, 2015 | 35 | 2015 |
Squaric acid analogues in medicinal chemistry J Chasák, V Šlachtová, M Urban, L Brulíková European Journal of Medicinal Chemistry 209, 112872, 2021 | 33 | 2021 |
Interaction of Human DNA Polymerase α and DNA Polymerase I from Bacillus stearothermophilus with Hypoxanthine and 8-Oxoguanine Nucleotides JN Patro, M Urban, RD Kuchta Biochemistry 48 (34), 8271-8278, 2009 | 33 | 2009 |