Vascularized and functional human liver from an iPSC-derived organ bud transplant T Takebe, K Sekine, M Enomura, H Koike, M Kimura, T Ogaeri, RR Zhang, ... Nature 499 (7459), 481-484, 2013 | 2308 | 2013 |
Multilineage communication regulates human liver bud development from pluripotency JG Camp, K Sekine, T Gerber, H Loeffler-Wirth, H Binder, M Gac, ... Nature 546 (7659), 533-538, 2017 | 546 | 2017 |
Vascularized and complex organ buds from diverse tissues via mesenchymal cell-driven condensation T Takebe, M Enomura, E Yoshizawa, M Kimura, H Koike, Y Ueno, ... Cell stem cell 16 (5), 556-565, 2015 | 485 | 2015 |
Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant T Takebe, RR Zhang, H Koike, M Kimura, E Yoshizawa, M Enomura, ... Nature protocols 9 (2), 396-409, 2014 | 422 | 2014 |
Modeling steatohepatitis in humans with pluripotent stem cell-derived organoids R Ouchi, S Togo, M Kimura, T Shinozawa, M Koido, H Koike, ... Cell metabolism 30 (2), 374-384. e6, 2019 | 405 | 2019 |
Massive and reproducible production of liver buds entirely from human pluripotent stem cells T Takebe, K Sekine, M Kimura, E Yoshizawa, S Ayano, M Koido, ... Cell reports 21 (10), 2661-2670, 2017 | 351 | 2017 |
Modelling human hepato-biliary-pancreatic organogenesis from the foregut–midgut boundary H Koike, K Iwasawa, R Ouchi, M Maezawa, K Giesbrecht, N Saiki, ... Nature 574 (7776), 112-116, 2019 | 277 | 2019 |
High-fidelity drug-induced liver injury screen using human pluripotent stem cell–derived organoids T Shinozawa, M Kimura, Y Cai, N Saiki, Y Yoneyama, R Ouchi, H Koike, ... Gastroenterology 160 (3), 831-846. e10, 2021 | 217 | 2021 |
Analysis of a germ line polymorphism of the p53 gene in lung cancer patients; discrete results with smoking history M Murata, M Tagawa, M Kimura, H Kimura, S Watanabe, H Saisho Carcinogenesis 17 (2), 261-264, 1996 | 148 | 1996 |
Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1B β and TSLC1 in neuroblastoma H Ochiai, H Takenobu, A Nakagawa, Y Yamaguchi, M Kimura, M Ohira, ... Oncogene 29 (18), 2681-2690, 2010 | 102 | 2010 |
En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH M Kimura, T Iguchi, K Iwasawa, A Dunn, WL Thompson, Y Yoneyama, ... Cell 185 (22), 4216-4232. e16, 2022 | 53 | 2022 |
Prospective phase II study of post-surgical adjuvant chemo-immunotherapy using autologous dendritic cells and activated killer cells from tissue culture of tumor-draining lymph … H Kimura, T Iizasa, A Ishikawa, M Shingyouji, M Yoshino, M Kimura, ... Anticancer Research 28 (2B), 1229-1238, 2008 | 51 | 2008 |
Optimal hypoxia regulates human iPSC-derived liver bud differentiation through intercellular TGFB signaling H Ayabe, T Anada, T Kamoya, T Sato, M Kimura, E Yoshizawa, S Kikuchi, ... Stem Cell Reports 11 (2), 306-316, 2018 | 49 | 2018 |
Effect of oxygen on in vitro differentiation of mouse embryonic stem cells H Kurosawa, M Kimura, T Noda, Y Amano Journal of bioscience and bioengineering 101 (1), 26-30, 2006 | 49 | 2006 |
Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells H Koike, K Iwasawa, R Ouchi, M Maezawa, M Kimura, A Kodaka, S Nishii, ... Nature protocols 16 (2), 919-936, 2021 | 40 | 2021 |
Bmi1 regulates cell fate via tumor suppressor WWOX repression in small‐cell lung cancer cells M Kimura, H Takenobu, N Akita, A Nakazawa, H Ochiai, O Shimozato, ... Cancer science 102 (5), 983-990, 2011 | 40 | 2011 |
Epigenetic silencing of Lgr5 induces senescence of intestinal epithelial organoids during the process of aging R Uchida, Y Saito, K Nogami, Y Kajiyama, Y Suzuki, Y Kawase, ... npj Aging and Mechanisms of Disease 4 (1), 12, 2018 | 39 | 2018 |
Efficient hepatic differentiation of human induced pluripotent stem cells in a three-dimensional microscale culture RR Zhang, T Takebe, L Miyazaki, M Takayama, H Koike, M Kimura, ... Stem Cells and Tissue Repair: Methods and Protocols, 131-141, 2014 | 35 | 2014 |
Transient vascularization of transplanted human adult–derived progenitors promotes self-organizing cartilage T Takebe, S Kobayashi, H Suzuki, M Mizuno, YM Chang, E Yoshizawa, ... The Journal of Clinical Investigation 124 (10), 4325-4334, 2014 | 33 | 2014 |
Temporal transition of mechanical characteristics of HUVEC/MSC spheroids using a microfluidic chip with force sensor probes K Ito, S Sakuma, M Kimura, T Takebe, M Kaneko, F Arai Micromachines 7 (12), 221, 2016 | 32 | 2016 |