| Identification of a cellularly active SIRT6 allosteric activator Z Huang, J Zhao, W Deng, Y Chen, J Shang, K Song, L Zhang, C Wang, ... Nature chemical biology 14 (12), 1118-1126, 2018 | 243 | 2018 |
| A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis T He, J Shang, C Gao, X Guan, Y Chen, L Zhu, L Zhang, C Zhang, ... Acta Pharmaceutica Sinica B 11 (3), 708-726, 2021 | 90 | 2021 |
| Peptidomimetic inhibitors of APC–Asef interaction block colorectal cancer migration H Jiang, R Deng, X Yang, J Shang, S Lu, Y Zhao, K Song, X Liu, Q Zhang, ... Nature chemical biology 13 (9), 994-1001, 2017 | 87 | 2017 |
| Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer L Wang, L Zhang, L Li, J Jiang, Z Zheng, J Shang, C Wang, W Chen, ... Science Advances 5 (9), eaax2277, 2019 | 76 | 2019 |
| MDL-800, an allosteric activator of SIRT6, suppresses proliferation and enhances EGFR-TKIs therapy in non-small cell lung cancer J Shang, S Ning, Y Chen, T Chen, J Zhang Acta Pharmacologica Sinica 42 (1), 120-131, 2021 | 46 | 2021 |
| Small-molecule activating SIRT6 elicits therapeutic effects and synergistically promotes anti-tumor activity of vitamin D3 in colorectal cancer J Shang, Z Zhu, Y Chen, J Song, Y Huang, K Song, J Zhong, X Xu, J Wei, ... Theranostics 10 (13), 5845, 2020 | 44 | 2020 |
| NAD+-consuming enzymes in immune defense against viral infection J Shang, MR Smith, A Anmangandla, H Lin Biochemical Journal 478 (23), 4071-4092, 2021 | 27 | 2021 |
| Allosteric modulators of MEK1: drug design and discovery J Shang, S Lu, Y Jiang, J Zhang Chemical Biology & Drug Design 88 (4), 485-497, 2016 | 24 | 2016 |
| Reply to: Binding site for MDL-801 on SIRT6 Z Huang, J Zhao, W Deng, Y Chen, J Shang, K Song, L Zhang, C Wang, ... Nature Chemical Biology 17 (5), 522-523, 2021 | 12 | 2021 |
| A Mitochondria-Targeting SIRT3 Inhibitor with Activity against Diffuse Large B Cell Lymphoma HL Sadhan Jana, Jialin Shang, Jun Young Hong, Michael K. Fenwick, Rishi Puri ... Journal of Medicinal Chemistry, 2024 | 1* | 2024 |
| GS-441524-diphosphate-ribose derivatives as nanomolar binders and fluorescence polarization tracers for SARS-CoV-2 and other viral macrodomains. HL Kewen Peng, Shamar D. Wallace, Saket R. Bagde, Jialin Shang, Ananya ... ACS Chemical Biology, 2024 | 1 | 2024 |
| Compound used as sirt6 small-molecule allosteric activator and pharmaceutical composition thereof XXU Jian Zhang, Yinyi CHEN, Cong Ruan, Xiuyan YANG, Chengxiang WANG, Qiufen ... US Patent US20220220069A1, 2022 | | 2022 |
| NAD (+)-consuming enzymes in immune defense against viral infection (vol 478, pg 4071, 2021) J Shang, MR Smith, A Anmangandla, H Lin BIOCHEMICAL JOURNAL 479 (5), 581-582, 2022 | | 2022 |
Jian ZhangShanghai Jiaotong University School of Medicine在 sjtu.edu.cn 的电子邮件经过验证
