IL4 induces IL6-producing M2 macrophages associated to inhibition of neuroinflammation in vitro and in vivo G Casella, L Garzetti, AT Gatta, A Finardi, C Maiorino, F Ruffini, G Martino, ... Journal of neuroinflammation 13, 1-10, 2016 | 165 | 2016 |
Extracellular vesicles containing IL-4 modulate neuroinflammation in a mouse model of multiple sclerosis G Casella, F Colombo, A Finardi, H Descamps, G Ill-Raga, A Spinelli, ... Molecular Therapy 26 (9), 2107-2118, 2018 | 124 | 2018 |
Potential roles of extracellular vesicles in the pathophysiology, diagnosis, and treatment of autoimmune diseases J Tian, G Casella, Y Zhang, A Rostami, X Li International journal of biological sciences 16 (4), 620, 2020 | 89 | 2020 |
Oligodendrocyte-derived extracellular vesicles as antigen-specific therapy for autoimmune neuroinflammation in mice G Casella, J Rasouli, A Boehm, W Zhang, D Xiao, LLW Ishikawa, ... Science translational medicine 12 (568), eaba0599, 2020 | 71 | 2020 |
Microvesicles: what is the role in multiple sclerosis? T Carandini, F Colombo, A Finardi, G Casella, L Garzetti, C Verderio, ... Frontiers in neurology 6, 111, 2015 | 55 | 2015 |
Role of extracellular vesicles in neurodegenerative diseases Y Xiao, SK Wang, Y Zhang, A Rostami, A Kenkare, G Casella, ZQ Yuan, ... Progress in Neurobiology 201, 102022, 2021 | 54 | 2021 |
Cytokines stimulate the release of microvesicles from myeloid cells independently from the P2X7 receptor/acid sphingomyelinase pathway F Colombo, M Bastoni, A Nigro, P Podini, A Finardi, G Casella, M Ramesh, ... Frontiers in immunology 9, 204, 2018 | 50 | 2018 |
A distinct GM-CSF+ T helper cell subset requires T-bet to adopt a TH1 phenotype and promote neuroinflammation J Rasouli, G Casella, S Yoshimura, W Zhang, D Xiao, J Garifallou, ... Science Immunology 5 (52), eaba9953, 2020 | 49 | 2020 |
IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression G Casella, A Finardi, H Descamps, F Colombo, C Maiorino, F Ruffini, ... Scientific reports 7 (1), 16547, 2017 | 37 | 2017 |
Myeloid extracellular vesicles: messengers from the demented brain A Nigro, F Colombo, G Casella, A Finardi, C Verderio, R Furlan Frontiers in Immunology 7, 17, 2016 | 29 | 2016 |
SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity W Zhang, D Xiao, X Li, Y Zhang, J Rasouli, G Casella, A Boehm, ... The Journal of Clinical Investigation 132 (22), 2022 | 26 | 2022 |
CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation D Hwang, MS Seyedsadr, LLW Ishikawa, A Boehm, Z Sahin, G Casella, ... Proceedings of the National Academy of Sciences 119 (14), e2111804119, 2022 | 22 | 2022 |
Polarized cells display asymmetric release of extracellular vesicles F Colombo, G Casella, P Podini, A Finardi, G Racchetti, EG Norton, ... Traffic 22 (4), 98-110, 2021 | 22 | 2021 |
Generation of oligodendrocyte progenitor cells from mouse bone marrow cells Y Zhang, XY Lu, G Casella, J Tian, ZQ Ye, T Yang, JJ Han, LY Jia, ... Frontiers in Cellular Neuroscience 13, 247, 2019 | 21 | 2019 |
Engineered extracellular vesicles encapsulated Bryostatin-1 as therapy for neuroinflammation WC Wu, J Tian, D Xiao, YX Guo, Y Xiao, XY Wu, G Casella, J Rasouli, ... Nanoscale 14 (6), 2393-2410, 2022 | 17 | 2022 |
IFN-β acts on monocytes to ameliorate CNS autoimmunity by inhibiting proinflammatory cross-talk between monocytes and Th cells J Rasouli, G Casella, LLW Ishikawa, R Thome, A Boehm, A Ertel, ... Frontiers in immunology 12, 679498, 2021 | 14 | 2021 |
CRISPR-mediated rapid generation of neural cell-specific knockout mice facilitates research in neurophysiology and pathology D Xiao, W Zhang, Q Wang, X Li, Y Zhang, J Rasouli, G Casella, B Ciric, ... Molecular Therapy-Methods & Clinical Development 20, 755-764, 2021 | 11 | 2021 |
A serine protease inhibitor suppresses autoimmune neuroinflammation by activating the STING/IFN-β axis in macrophages G Casella, J Rasouli, K Mason, A Boehm, G Kumar, D Hwang, R Thome, ... Cellular & Molecular Immunology 17 (12), 1278-1280, 2020 | 10 | 2020 |
Interferon-γ/Interleukin-27 axis induces programmed death ligand 1 expression in monocyte-derived dendritic cells and restores immune tolerance in central nervous system … G Casella, J Rasouli, R Thome, HC Descamps, A Vattikonda, L Ishikawa, ... Frontiers in immunology 11, 576752, 2020 | 9 | 2020 |
Interferon-gamma ameliorates experimental autoimmune encephalomyelitis by inducing homeostatic adaptation of microglia JE Tichauer, G Arellano, E Acuña, LF González, NR Kannaiyan, P Murgas, ... Frontiers in immunology 14, 1191838, 2023 | 8 | 2023 |