关注
Giacomo Casella
Giacomo Casella
Spark Therapeutic, Inc.
在 sparktx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
IL4 induces IL6-producing M2 macrophages associated to inhibition of neuroinflammation in vitro and in vivo
G Casella, L Garzetti, AT Gatta, A Finardi, C Maiorino, F Ruffini, G Martino, ...
Journal of neuroinflammation 13, 1-10, 2016
1652016
Extracellular vesicles containing IL-4 modulate neuroinflammation in a mouse model of multiple sclerosis
G Casella, F Colombo, A Finardi, H Descamps, G Ill-Raga, A Spinelli, ...
Molecular Therapy 26 (9), 2107-2118, 2018
1242018
Potential roles of extracellular vesicles in the pathophysiology, diagnosis, and treatment of autoimmune diseases
J Tian, G Casella, Y Zhang, A Rostami, X Li
International journal of biological sciences 16 (4), 620, 2020
892020
Oligodendrocyte-derived extracellular vesicles as antigen-specific therapy for autoimmune neuroinflammation in mice
G Casella, J Rasouli, A Boehm, W Zhang, D Xiao, LLW Ishikawa, ...
Science translational medicine 12 (568), eaba0599, 2020
712020
Microvesicles: what is the role in multiple sclerosis?
T Carandini, F Colombo, A Finardi, G Casella, L Garzetti, C Verderio, ...
Frontiers in neurology 6, 111, 2015
552015
Role of extracellular vesicles in neurodegenerative diseases
Y Xiao, SK Wang, Y Zhang, A Rostami, A Kenkare, G Casella, ZQ Yuan, ...
Progress in Neurobiology 201, 102022, 2021
542021
Cytokines stimulate the release of microvesicles from myeloid cells independently from the P2X7 receptor/acid sphingomyelinase pathway
F Colombo, M Bastoni, A Nigro, P Podini, A Finardi, G Casella, M Ramesh, ...
Frontiers in immunology 9, 204, 2018
502018
A distinct GM-CSF+ T helper cell subset requires T-bet to adopt a TH1 phenotype and promote neuroinflammation
J Rasouli, G Casella, S Yoshimura, W Zhang, D Xiao, J Garifallou, ...
Science Immunology 5 (52), eaba9953, 2020
492020
IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression
G Casella, A Finardi, H Descamps, F Colombo, C Maiorino, F Ruffini, ...
Scientific reports 7 (1), 16547, 2017
372017
Myeloid extracellular vesicles: messengers from the demented brain
A Nigro, F Colombo, G Casella, A Finardi, C Verderio, R Furlan
Frontiers in Immunology 7, 17, 2016
292016
SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity
W Zhang, D Xiao, X Li, Y Zhang, J Rasouli, G Casella, A Boehm, ...
The Journal of Clinical Investigation 132 (22), 2022
262022
CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation
D Hwang, MS Seyedsadr, LLW Ishikawa, A Boehm, Z Sahin, G Casella, ...
Proceedings of the National Academy of Sciences 119 (14), e2111804119, 2022
222022
Polarized cells display asymmetric release of extracellular vesicles
F Colombo, G Casella, P Podini, A Finardi, G Racchetti, EG Norton, ...
Traffic 22 (4), 98-110, 2021
222021
Generation of oligodendrocyte progenitor cells from mouse bone marrow cells
Y Zhang, XY Lu, G Casella, J Tian, ZQ Ye, T Yang, JJ Han, LY Jia, ...
Frontiers in Cellular Neuroscience 13, 247, 2019
212019
Engineered extracellular vesicles encapsulated Bryostatin-1 as therapy for neuroinflammation
WC Wu, J Tian, D Xiao, YX Guo, Y Xiao, XY Wu, G Casella, J Rasouli, ...
Nanoscale 14 (6), 2393-2410, 2022
172022
IFN-β acts on monocytes to ameliorate CNS autoimmunity by inhibiting proinflammatory cross-talk between monocytes and Th cells
J Rasouli, G Casella, LLW Ishikawa, R Thome, A Boehm, A Ertel, ...
Frontiers in immunology 12, 679498, 2021
142021
CRISPR-mediated rapid generation of neural cell-specific knockout mice facilitates research in neurophysiology and pathology
D Xiao, W Zhang, Q Wang, X Li, Y Zhang, J Rasouli, G Casella, B Ciric, ...
Molecular Therapy-Methods & Clinical Development 20, 755-764, 2021
112021
A serine protease inhibitor suppresses autoimmune neuroinflammation by activating the STING/IFN-β axis in macrophages
G Casella, J Rasouli, K Mason, A Boehm, G Kumar, D Hwang, R Thome, ...
Cellular & Molecular Immunology 17 (12), 1278-1280, 2020
102020
Interferon-γ/Interleukin-27 axis induces programmed death ligand 1 expression in monocyte-derived dendritic cells and restores immune tolerance in central nervous system …
G Casella, J Rasouli, R Thome, HC Descamps, A Vattikonda, L Ishikawa, ...
Frontiers in immunology 11, 576752, 2020
92020
Interferon-gamma ameliorates experimental autoimmune encephalomyelitis by inducing homeostatic adaptation of microglia
JE Tichauer, G Arellano, E Acuña, LF González, NR Kannaiyan, P Murgas, ...
Frontiers in immunology 14, 1191838, 2023
82023
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