Modelling human development and disease in pluripotent stem-cell-derived gastric organoids KW McCracken, EM Catá, CM Crawford, KL Sinagoga, M Schumacher, ... Nature 516 (7531), 400-404, 2014 | 1012 | 2014 |
Generating human intestinal tissue from pluripotent stem cells in vitro KW McCracken, JC Howell, JM Wells, JR Spence Nature protocols 6 (12), 1920-1928, 2011 | 457 | 2011 |
Wnt/β-catenin promotes gastric fundus specification in mice and humans KW McCracken, E Aihara, B Martin, CM Crawford, T Broda, J Treguier, ... Nature 541 (7636), 182-187, 2017 | 241 | 2017 |
Esophageal organoids from human pluripotent stem cells delineate Sox2 functions during esophageal specification SL Trisno, KED Philo, KW McCracken, EM Catá, S Ruiz-Torres, ... Cell Stem Cell 23 (4), 501-515. e7, 2018 | 146 | 2018 |
A retinoic acid-hedgehog cascade coordinates mesoderm-inducing signals and endoderm competence during lung specification SA Rankin, L Han, KW McCracken, AP Kenny, CT Anglin, EA Grigg, ... Cell reports 16 (1), 66-78, 2016 | 125 | 2016 |
Mutations in SOX17 are associated with congenital anomalies of the kidney and the urinary tract S Gimelli, G Caridi, S Beri, K McCracken, R Bocciardi, P Zordan, ... Human mutation 31 (12), 1352-1359, 2010 | 88 | 2010 |
Arx is required for normal enteroendocrine cell development in mice and humans A Du, KW McCracken, ER Walp, NA Terry, TJ Klein, A Han, JM Wells, ... Developmental biology 365 (1), 175-188, 2012 | 86 | 2012 |
Generation of human antral and fundic gastric organoids from pluripotent stem cells TR Broda, KW McCracken, JM Wells Nature protocols 14 (1), 28-50, 2019 | 77 | 2019 |
Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis SA Rankin, KW McCracken, DM Luedeke, L Han, JM Wells, JM Shannon, ... Developmental biology 434 (1), 121-132, 2018 | 66 | 2018 |
Molecular pathways controlling pancreas induction KW McCracken, JM Wells Seminars in cell & developmental biology 23 (6), 656-662, 2012 | 66 | 2012 |
Mechanisms of embryonic stomach development KW McCracken, JM Wells Seminars in cell & developmental biology 66, 36-42, 2017 | 60 | 2017 |
Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas Y Suissa, J Magenheim, M Stolovich-Rain, A Hija, P Collombat, ... PloS one 8 (8), e70397, 2013 | 52 | 2013 |
Human ureteric bud organoids recapitulate branching morphogenesis and differentiate into functional collecting duct cell types M Shi, KW McCracken, AB Patel, W Zhang, L Ester, MT Valerius, ... Nature biotechnology 41 (2), 252-261, 2023 | 36 | 2023 |
Methods and systems for converting precursor cells into gastric tissues through directed differentiation JM Wells, KW Mccracken US Patent 10,174,289, 2019 | 28 | 2019 |
Orphan nuclear receptor COUP‐TFII enhances myofibroblast glycolysis leading to kidney fibrosis L Li, P Galichon, X Xiao, AC Figueroa‐Ramirez, D Tamayo, JJK Lee, ... EMBO reports 22 (6), e51169, 2021 | 23 | 2021 |
Using Human Induced Pluripotent Stem Cell–Derived Organoids to Identify New Pathologies in Patients With PDX1 Mutations M Krishnamurthy, DO Kechele, T Broda, X Zhang, JR Enriquez, ... Gastroenterology 163 (4), 1053-1063. e7, 2022 | 12 | 2022 |
Mechanisms of endoderm patterning and directed differentiation of human stem cells into foregut tissues KW McCracken University of Cincinnati, 2014 | 7 | 2014 |
Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same J Wells, K McCracken US Patent 11,066,650, 2021 | 4 | 2021 |
Methods and systems for converting precursor cells into gastric tissues through directed differentiation JM Wells, KW Mccracken US Patent 11,053,477, 2021 | 4 | 2021 |
Methods and systems for converting precursor cells into gastric tissues through directed differentiation JM Wells, KW Mccracken US Patent App. 17/305,196, 2022 | 2 | 2022 |